Acute Care Dysglycemia Flashcards

(54 cards)

1
Q

How often do you monitor a patient’s glucose level if they are on an IV insulin drip?

A

every 30 min to 2 hours

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2
Q

How often do you monitor a patient’s glucose level if they are on a TPN or enteral nutrition?

A

Q4H

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3
Q

How often do you monitor a patient’s glucose level if they are NPO?

A

Q4-6H

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4
Q

How often do you monitor a patient’s glucose level if they are a regular patient in the hospital?

A

Q6H for at least the first 48 hours

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5
Q

How often do you monitor a patient’s glucose level if they are stable?

A

Q8-12H

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6
Q

What are the glucose goals for patients in the medical-surgical ward?

A

Random: less than 180
Fasting: less than 140

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7
Q

What are the glucose goals for patients in the ICU? What if the patient is in SICU or CICU?

A

Random: 180 or less
Goal range: 140-180

SICU/CICU: 110-140

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8
Q

How often should an insulin sliding scale be adjusted?

A

every 1-2 days

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9
Q

What patients should receive an insulin infusion?

A

• hyperglycemic crisis
• poorly controlled DM despite SC insulin
– BG > 350 mg/dL for more than 12 hrs
• TPN + uncontrolled hyperglycemia
• DM pts who are NPO, preoperative, or in Labor & Delivery (L&D)
• post-MI or ACS patients with hyperglycemia
• Any ICU patient with hyperglycemia

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10
Q

How do you prepare an insulin infusion?

A

Mix 100 units of regular insulin in 100 cc of 0.9% NaCl (or 0.45% NaCl)

Run at least 20 cc through the tubing before initiating infusion (to prevent the insulin from sticking to the tubing)

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11
Q

What is the initial dose for patients on a insulin infusion? When would this rate be higher?

A

0.1-0.15 units/kg

Rate may be higher in those who are . . . 
• insulin-resistant
• obese
• on steroids
• severely hyperglycemic
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12
Q

How often should you check a patient’s glucose level if they are on an insulin infusion?
What is the goal for decreasing the BG?

A

every hour for 4-6 hours until patient is stable

Goal: decrease BG ~ 50-75 mg/dL

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13
Q

What are the general rules for adjusting an insulin infusion?

A

if BG decreases by > 100 mg/hr —> decrease rate by 25-50%

if BG increases or no change after 1-2 h —> increase rate by 50-100%

if BG is within goal targets —> continue same rate

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14
Q

Before transitioning from IV —> SQ insulin you should give . . .

A

short/rapid-acting insulin 1-2 hours before stopping the IV OR
intermediate/long-acting 2-3 hours before stopping the IV

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15
Q

What is one approach to switching from insulin infusion (IV) —> SQ insulin?

A
  1. determine the average hourly IV insulin rate for the past 6 hours
  2. multiply the number by 20 to get average adjusted TDD!
    • give 50% as BASAL insulin
    Detemir q 12 h or Glargine q 24 h
    NPH q 12 h
    • give 50% as BOLUS dose in divided doses (divide by 3)
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16
Q

What are some Precipitating Factors that may cause hyperglycemic crisis?

A
  1. Infection
  2. Inadequate insulin therapy or noncompliance
  3. New onset diabetes
  4. Other acute illness (CVA, AMI, pancreatitis)
  5. Medications
    • Corticosteroids
    • Thiazides
    • Sympathomimetic agents (ex. dobutamine, epinephrine)
    • Antipsychotic medications (ex. Quetiapine)
    • SGLT2 inhibitors (May 2015)
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17
Q

Absolute and/or relative insulin deficiency and elevated counter regulatory hormones which results in hyperglycemia

A

hyperglycemic crisis

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18
Q

Absolute and/or relative insulin deficiency and elevated counter regulatory hormones which results in hyperglycemia

A

hyperglycemic crisis

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19
Q

Clinical presentation of DKA and HHS?

A
polyuria
polydipsia
weight loss
dehydration
poor skin trudger
tachycardia
hypotension
mental status change
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20
Q

DKA develops within . . .

A

hours

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21
Q

HHS develops within . . .

A

days to weeks

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22
Q

_______ may have a Fruity breath odor

23
Q

______ has Kussmaul respirations

24
Q

______ has Kussmaul respirations

25
_______ presents with a glucose > 250 mg/dL
DKA
26
_______ presents with a glucose > 600 mg/dL
HHS
27
_______ presents with a pH ≤ 7.3
DKA
28
_______ presents with a bicarb level > 18
HHS
29
_______ presents positive for ketones
DKA
30
_______ presents positive for ketones
DKA
31
DKA is caused by an __________ insulin deficiency. a. relative b. absolute
b. absolute
32
DKA is caused by an __________ insulin deficiency. a. relative b. absolute
b. absolute
33
Considered a hyperosmolality state
HHS
34
Calculate a patient’s anion gap.
anion gap (mEq/L) = Na+ - (HCO3- + Cl-)
35
Calculate a patient’s corrected Na+ level.
Corrected serum Na+ (mEq/L) = Na+ + [0.016 x (BG -100)] Normal Na+ = 135-145 mEq/L
36
Calculate a patient’s corrected Na+ level.
Corrected serum Na+ (mEq/L) = Na+ + [0.016 x (BG -100)] Normal Na+ = 135-145 mEq/L
37
What are the types of treatment we give for DKA or HHS?
``` Treatment: (give all ASAP) Fluid therapy Insulin therapy Electrolyte correction (K+, PO4-, Mag) Bicarbonate therapy Identify & treat co-morbid precipitating events ```
38
Fluid therapy: | hour 1: give . . .
give 0.9% NaC; (normal saline) | rate 15-20 mL/kg/h or 1-1.5 L/h
39
Fluid therapy: | hour 2+: give . . .
Hour 2+: fluids are guided by corrected serum Na+ & BG: Normal or elevated Na+: 0.45% NaCl (half-normal saline) Low Na+: 0.9% NaCl (normal saline) Rate: 250-500 mL/h
40
Monitor BG & switch to mixed D5W & 0.45% NaCl when:
DKA: BG ≤ 200 mg/dL HHS: BG ≤ 300 mg/dL New Rate: 150-250 mL/h
41
What should you monitor in patients with cardiac complications?
closely monitor serum osmolality as well as cardiac, renal, and mental status to avoid fluid overload
42
Insulin therapy:
Regular insulin: Option 1: 0.14 units/kg/h Option 2: 0.1 units/kg IV bolus followed by 0.1 units/kg/h If BG does not decrease by at least 10% in the 1st hour, give 0.14 units/kg IV bolus, then continue previous continuous IV infusion
43
Decrease insulin infusion to 0.02-0.05 units/kg/h when . . .
DKA: BG
44
Check _____ level before initiating insulin therapy.
K+
45
If K+ is less than 3.3 mEq/L:
hold insulin until K+ > 3.3 mEq/L (b/c insulin decreases K+ levels) replete K+ with 20-30 mEq/L/h
46
If K+ > 5.2 mEq/L:
initiate insulin infusion No K+ in infusion fluid Monitor K+ level every 2 hours until
47
If K+ > 5.2 mEq/L:
initiate insulin infusion No K+ in infusion fluid Monitor K+ level every 2 hours until
48
When would you replace phosphate or magnesium?
indication for replacement: | phosphate
49
What therapy do you give in DKA only?
bicarbonate therapy
50
bicarbonate therapy NOT recommended when pH is __________
≥ 6.9
51
Normal bicarbonate:
22-26 mEq/L
52
DKA is considered resolved when:
DKA: BG 7.3 • Anion gap ≤ 12 mEq/L
53
DKA is considered resolved when:
DKA: BG 7.3 • Anion gap ≤ 12 mEq/L
54
HHS is considered resolved when:
normal serum osmolality: 280-320 mOsm/kg | normal mental status