Acute hepatitis

Question 1

Acute hepatitis definition

Answer 1

Inflammation of the liver with little-no fibrosis or nodular regeneration

Question 2

Main categories of causes of acute hepatitis

Answer 2

1. Infection
2. Chemical toxicity
3. Pregnancy

Question 3

Typical symptoms of acute hepatitis

Answer 3

Fever
Malaise, myalgia
RUQ pain, tender hepatomegaly
N/V, diarrhoea
Jaundice, pruritis

Question 4

Specific causes under INFECTIVE causes of acute hepatitis

Answer 4

Hepatitis A, B, C, E
CMV
Infectious mononucleosis
Amoebic infection
Sepsis

Question 5

Most common causes of acute hepatitis

Answer 5

Hepatitis A infection

Question 6

Specific causes under CHEMICAL TOXICITY for acute hepatitis

Answer 6

Paracetamol
Methotrexate
Isoniazid
Rifampicin
Alcohol

Question 7

Hep A serology shows elevated IgM, no IgG

Interpretation?

Answer 7

Recent/active infection

Question 8

Hep A serology shows no IgM, elevated IgG

Interpretation?

Answer 8

Immune

previous infection/vaccination

Question 9

Hep A treatment

Answer 9

Supportive care

Question 10

How long does Hep A take to resolve?

Answer 10

from 2 weeks to 4 months

Question 11

Hep A immunisation,

for who?

Answer 11

ATSI children in NT, QLD, SA, WA

Question 12

Hep A immunisation,

when?

Answer 12

18 months and 4 years of age

for ATSI children

Question 13

Hepatitis A transmitted via ___ route

Answer 13

fecal-oral

Question 14

Hepatitis B transmitted via ____ route

Answer 14

exchange of body fluids

IV, sexual fluids, mother-child

Question 15

Hep B symptoms start __(time period)__ after infection

Answer 15

6 weeks-6 months

Question 16

Acute Hep B symptoms include symptoms of acute hepatitis AND SOMETIMES other features, which are:

Answer 16

• Polyarthritis
• Skin rashes
• Glomerulonephritis