Acute Ischemic Heart Disease - Yaacoub Flashcards

(40 cards)

1
Q

ASA contraindicated in

A

severe aspirin allergy

Implement desensitization

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2
Q

NonSTEMI can also be associated with

A

normal ECG

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3
Q

Preferred clopidogrel strategy

A

Pretreatment

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4
Q

29% reduction in death/MI in PCI patients

A

Clopidogrel Tx

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5
Q

RV infarction

A

HoTN

JVD

Clear lungs

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6
Q

Most important criteria in TIMI risk score

A

Age >65

>3 risk factors for CAD
ST changes

Prior coronary stenosis

> 2 anginal episodes in the past day

Elevated cardiac markers

Use of ASA within 7 days

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7
Q

RRR (relative risk reduction) of ____ with early invasive intervention

A

49%

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8
Q

In first 24 hours, __ STEMI patients and __ NSTEMI patients

A

26%

14%

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9
Q

4 Highest reductions in mortality

A
  1. Heparin, ASA
  2. BB
  3. Cath
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10
Q

Nitrates contraindicated in patients with

A

RV infarction

PDE inhibitors

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11
Q

Relative risk of death in ST changes

A

T wave inv = 62%

STE= 68%

STD = 2.27

**ST depression is the worst prognostic marker

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12
Q

___ has higher bleeding complications and lower combined endpoints of death/MI/revascularization

A

Prasugrel

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13
Q

Low risk ACS

A

New-onset or progressive CCS class 3 or 4

Normal or unchanged ECG during chest discomfort

Normal cardiac markers

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14
Q

Avoid BB with

A

intrinsic sympatholytic activity

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15
Q

Global diffuse ST changes without reciprocation

A

pericarditis

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16
Q

Which risk is higher, No troponin and CAD, or +troponin and no CAD

A

No troponin and CAD

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17
Q

May use __ as substitute for ASA

18
Q

abciximab + heparin is most beneficial for patients with

A

troponin elevation

(vs. just heparin)

19
Q

Score 6/7 is the greatest risk, at ___%

20
Q

Use 2b3a in whom

A

those who are at higher risk

benefit most profound with stented diabetics

21
Q

Intermed risk patients for ACS

A

Prior MI, PVD, or CABG

Prolonged rest angina now resolved

Rest angina under 20 min

Age above 70

T wave inversions >.2mV

Pathological Q waves

Slightly elevated cardiac markers

22
Q

Risk stratification based on

A

TIMI risk score

23
Q

Everyone with Stent and most with PCI get

24
Q

Acute anterior wall MI is what vessel

25
Reduces mortality by approximately 50%
ASA
26
In-hospital early interventions
Early Diabetes control Eary ________ control
27
High risk in ACS
* Accelerating ischmic Sx * \>20 min rest pain * Pulm Edema * MR murmur (new or worse) * S3 * New/worse rales * HoTN * Age \>75 * ST changes \>.05mV
28
ST depression or T wave inversion means either
Unstable angina or NSTEMI
29
Pathophys of ACS
Plaque rupture Blood clot Blding into plaque accompanies rupture
30
Angina pectoris definition
acute ischemic chest pain with either res pain or a crecendo pattern of pain on minimal exertion associated with ECG changes of ischemia
31
Can have a completely normal ECG with \_\_\_\_
significant disease of the circumflex artery
32
2b3a is given over what time period
12-16 hrs
33
CI's for beta blockers
* HoTN * Severe bronchospasm * Bradycardia (heart block) * Suspected Prinzmetal or cocaine (spasm)
34
additional _____ reduction in use of LMWH vs \_\_\_
12% Unfractionated
35
Continue plavix for
one year or longer
36
ST segment elevation in aVR is marker for
Left Main coronary disease
37
2b3a inhibitors reserved for
patients in or going to cath lab prevents platelet aggregation via 2b3a antagonism
38
Deep and symmetrical T wave inversion (that is usually global) in multiple leads, accompanied with headace
Intracranial hemorrhage
39
9% reduction in death/MI at 30 days
gp2b3a inhibitors
40
Invasive prrefered with:
* Recurrent Ischemia * CHF * Cardiogenic shock * Hx of PCI in the past 6 months * Previous CABG