Acute Medicine Flashcards

(42 cards)

1
Q

What is the APLS algorithm including;

  • 4H’s + 4T’s
  • Post resuscitation care
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

How long should you continue resuscitation for with good quality CPR?

A

30 minutes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the shockable rhythms?

What shock do you deliver?

A

VF + pulseless VT

4J/kg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the 4 types of shock?

A
  • Cardiogenic
  • Hypotensive
  • Septic
  • Anaphylactic
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Describe the difference between a vasopressor + inotrope:

A
  • Vasopressor: vasoconstriction and increases MAP
  • Inotrope: cardiac + vascular effects: increases contractility + chronotropy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Effect, receptor + use of;

  • Noradrenaline
  • Adrenaline
  • Dopamine
  • Dobutamine
  • Milrinone
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Where does the spinal cord lie in this picture?

What is line A + B + C

A
  • Spinal cord lies between B + C
  • A = anterior vertebral line
  • B = posterior vertebral line
  • C = spinolaminar line
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the normal soft tissue dimensions in the cervical spine?

A

Above the larynx C2 : < 1/3 of the vertebral body width

Below the larynx C3-7: <1 vertebral body wifth

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What does the median nerve supply?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What does the ulna nerve supply?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What sort of fracture is this?

A

Buckle fracture: no breach of cortex

Only requires a splint

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What type of # is this + what nerve is commonly injured?

A

Monteggia fracture-dislocation refers to dislocation of the radial head (proximal radioulnar joint) with fracture of the ulna.

  • Anterior dislocation of the radial head is most common
  • Radial nerve is most commonly injured
  • Also look out for plastic deformation of the ulna
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What type of # is this?

A

Galeazzi fracture-dislocation

  • Fracture of the distal third of the shaft of the radius with a disruption to the distal radiual ulna joint (DRUJ)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the radiocapitellar line?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What overdose is MOST likely for a patient with the following ECG:

A

Tricyclic antidepressant overdose

  • Right axis deviation
  • Tall R wave in aVR
  • QTc prolongation (predisposing to VT + VF) due to K blockade
  • QRS prolongation
    • >100ms seizures
    • >160 VT/VF
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the pathophysiology of tricyclic antidepressant overdose?

A
  • Central + peripheral ACh receptor blockade (anticholinergic)
    • Dilated pupils
    • Tachycardia
    • Vomiting
    • Delirium, confusion, myoclonic jerks, seizures, ataxia, blurred vision
    • Urinary reterntion, ileus
  • Fast Na channel blockade
    • Increases duration of repolarisation + refractory period
  • Noradrenaline + serotonin reuptake blockade
    • CNS depression / coma
    • Seizures
  • Alpha adrenergic receptor blockade
    • Hypotension
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Treatment of sodium bicarbonate

A
  • ABCDE’s
  • IV access: 1-2mmol/kg sodium bicarbonate
  • Intubate + hyperventilate (aim pH 7.5-7.55)
  • NGT + charcoal (generally contraindicated but can consider within 2 hrs)
  • IV midazolam for seizures (PHENYTOIN CONTRAINDICATED)
  • Fluid bolus for hypotension +/- noradrenaline
  • If further arrhythmias repeat NaHCO3 then lignocaine
18
Q

Pathophysiology of carbon monoxide poisoning

A
  • Impaired oxygen offloading + impaired peripheral oxygen utilisation
    • Binds to iron moiety of haem with x240 affinity of O2
    • Allosteric change in haem protein = reduced ability of other three O2 binding sites to offload in the peripheral tissues = LEFT shift of O2 curve
19
Q

What are the 3 snake antivenoms we have in Aus?

  • Give if any evidence of neurotoxic paralysis: ptosis, opthalmoplegia, limb weakness, respiratory effects, significant coagulopathy INR >1.3 of prolonged bleeding, history of unconsciousness, collapse, seizure, arrest
A
  • Black snake
    • Rhabdomyolysis
    • Anosmia long term sequelae
    • Local signs at bite site ++
  • Brown snake
    • Most common cause of fatal snake bite
    • Defibrinating coagulopathy
    • Neurotoxicity rare
    • Rhabdomyolysis does NOT occur
    • Collapse 1/3 + arrest 5%
  • Tiger snake
    • Paralysis + rhabdomyolysis over hours
20
Q

Anticholinergic vs sympathomimetic

A

Picking = anticholinergic

21
Q

Serotonin syndrome features

22
Q

Serotonin syndrome vs. Neuroleptic malignant syndrome

23
Q

What does the handlebar sign indicate?

A
  • Duodenal perforation
  • Liver bleed
  • Spleen bleed

Need to be admitted for serial examination despite normal CT scan as high risk for duodenal perforation

24
Q

Younger children are more likely to have c-spine injuries where?

A

C1-3 whereas older children C3 onwards more likely

25
Location of needle decompression for pneumothorax Location of chest drain insertion
Needle decompression: mid clavicular line 2nd intercostal space Chest drain: 4-5th intercostal space mid axillary line
26
What is the treatment for raised ICP in trauma?
* Positioning * Sedation + analgesia * Controlled hyperventilation * Hyperosmolar therapy * 3% saline 3mL/kg
27
What are toxicology causes of hypoglycaemia?
* Beta blockers * Insulin * Oral hypogllycaemia agents * Quinine * Valproic acid * Saliculate
28
What drug is contraindicated in toxicology seizures?
Phenytoin: acts on sodium channel (many of the toxicology agents act on the Na channel)
29
What are toxicology causes of seizures?
* Venlafazine * Bupropion * Tramadol * Amphetamine
30
In toxicology what is the indication for neuromuscular paralysis?
Temp \> 39.5 Need neuromuscular paralysis to prevent multi-organ failure
31
Specific antidotes: * Tricyclic antidepressant * Cholinergic syndrome (Organophosphate poisoning) * Anticholinergic syndrome * Digoxin * Paracetamol * Opiates
* Tricyclic antidepressant * _Sodium bicarbonate_ * Organophosphate poisoning * _Atropine_ * Anticholinergic syndrome * IV fluids * Diazepamfor agitation * Physostigmine * Digoxin * Digibind * Paracetamol * NAC * Opiates * Naloxone
32
Toxicology: how does fast sodium channel blockade overdose manifest on an ECG?
* Widening of QRS in lead II * Right axis deviation * Bradycardia * VT + VF
33
Toxicology: how does blockade of K+ efflux overdose manifest on an ECG?
QT prolongation --\> Torsades ---\> VF
34
Decontamination in paediatrics
* Induced emesis + gastric lavage: NOT used * Single dose of activated charcoal: USED in paeds * Super heated distilled wood pulp * Aspiration is a risk * Does NOT work very well for: hydrocarbons/alcohol, metals, corrosives (acids/alkalis) * Whole bowel washout: USED in paeds * Polyethylene glycol electrolyte solution used + continue until faeces is clear * Useful in iron overdose (\>60mg/kg), SR K+, diltiazem, verapamil, arsenic, lead ingestion, "body packers"
35
Techniques for enhancing elimination in toxic ingestions * Multiple dose activated charcoal * Urinary alkalinisation * Haemodyalysis + haemofiltration * Charcoal haemoperfusion
* Multiple dose activated charcoal * Carbamazepine * Urinary alkalinisation * Salicylates * Phenobarbitone * Haemodyalysis + haemofiltration * Lithium * Metformin lactic acidosis * Salicylates * K+ * Charcoal haemoperfusion * Theophylline
36
37
Serotonin syndrome features + management
* Mental state changes * Agitation, confusion, anxiety * Autonomic stimulation * Diarrhoea, flushing, hypertension, fever, sweating, mydriasis, tachycardia * Neuromuscular excitation * Clonus, hyperreflexia, increased tone, rigidity, tremor _Management_ * Diazepam for seizures * Cyproheptadine
38
Drugs of abuse that can cause serotonin syndrome
* Amphetamines * MDMA; ecstasy
39
Signs + symptoms of cholinergic syndrome
**D**iarrhoea **U**rination **M**iosis **B**ronchosplasm **E**mesis **L**acrimation **S**alivation
40
Most common cause of cholinergic syndrome
Organophosphate poisoning
41
42