Acute rheumatic fever 1B

Question 1

What is the causative infectious organism in rheumatic fever?

Answer 1

Group A streptococci

Question 2

What types of inflammatory lesions are formed due to rheumatic fever?

Answer 2

exudative and proliferative

Question 3

Connective e tissues of what organs are mainly affected by the exudative and proliferative inflammatory lesions?

Answer 3

Heart, joints and subcutaneous tissues

Question 4

What is the range of time from infection to the onset of the symptom?

Answer 4

1-5weeks

Question 5

What is the pathophysiology of rheumatic fever?

Answer 5

unknown

Question 6

Peak incidence of rheumatic fever is between what age group?

Answer 6

5-15 years old

Question 7

What criterion is used to stratify the signs and symptoms of rheumatic fever?

Answer 7

Jones criteria

Question 8

What are the 5 main major clinical manifestations of rheumatic fever according to Jones criteria?

Answer 8

Carditis, polyarthritis, chorea, ethythema marginatum, subcutaneous nodules

Question 9

What is the clinical manifestation of carditis on a patient with rheumatic fever? I

Answer 9

It can be any of the following or more; cardiac murmur, cardiomegaly, pericarditis congestive heart failure

Question 10

What is the mnemonic for the minor criteria?

Answer 10

CAFÉ PAL; CRP, Arthralgia, fever, ESR, PR(prolonged) Anamnesis of Rheumatism, Leukocytosis

Question 11

When recent streptococcal infection is noted, what can be done?

Answer 11

Throat cultures growing GABHS or elevated anti-streptolysin O titers

Question 12

How is the diagnosis with Jones criteria based on?

Answer 12

2 major criteria or 1 major criteria +2 minor criteria

Question 13

hat else is considered in the treatment

Answer 13

bed rest, anti-inflammatory for symptoms, aspirin, corticosteroid if no response to aspirin