Adaptiv Föreläsning Flashcards by Natthawadee Jaroensuk | Brainscape

Q

Hur tar sig naiva lymfocyter in i SLOs?

A

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Q

Lymfocyternas går till sina särskilda platser med
kemotaktisk migration

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Q

Sekundära lymfoida organens organisation/ mjälte

A

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Q

Lymfocyternas förmåga att detektera mikrob-varianter beror på
antigenspecifika receptorernas variationsrikedom

A

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Q

T cellen detekterar ”sitt specifika antigen” med TCR
presenterat på MHC på en DC i SLO

A

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Q

CTLA4

A

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Q

PD1

A

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Q

Olika Th

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Q

Th1

A

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Q

Th1

A

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Q

Th1 cellens effektorfunktioner

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Q

Th2 cellens effektorfunktion

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Q

Th17 cellens effektorfunktion

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Q

CD8+ Tc cellens aktivering

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Q

DC MHCI precentering

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Q

Lethal hit

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Q

CTL har sekretoriska vesikler

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Q

Antikroppen grek

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Q

Ig-molekylen kan uttryckas både i
membranbunden (mIg) och sekretorisk form (sIg)

A

Q

Antikroppar
B cellens olika differentieringsstadier

A

Q

Antikropparnas funktion och distribution

A

Q

Antikropparnas funktion

A

Q

Neutralisering

A

Q

Opsonisering

A

Q

Klassiska aktiveringsvägen av komplementsystemet

A

Q

ADCC
(Antibody dependent cellular cytotoxicity)

A

Q

Aktiverar mastceller

A

Q

T-cellsoberoende B-cellsaktivering

A

Q

Samarbetet mellan T och B celler: cellerna möts

A

Q

Antikroppsmedierade immunförsvaret

A

Q

Den aktiverade B cellen

A

Q

Vid systemisk infektion

A

Q

Isotype switch

A

Q

Upprepad immunisering illustrerar antikroppssvarets
Affinitetsmognad

A

Q

Hur skapar vi tolerans mot oss själva?

A

Q

Perifer T cells tolerans olika sätt

A

Q

Perifer T cells tolerans

A

Q

AIRE

A

Q

Perifer T cells tolerans

A

Q

Naturliga CD4 regulatoriska T-celler
(tTreg)

A

Q

Negativ selektion & Agonistselektion - Tregs
AIRE
The autoimmune regulator protein

A

Q

Inducerbara Tregs (iTregs)

A

Q

Treg
Generella mekanismer

A

Q

Sammanfattning Tregs
Funktion

A

Q

Sammanfattning perifer T cells tolerans

A

Q

B-cells tolerans

A

Q

Viktiga punkter

A