Addiction

Question 0

What do opiates do

Answer 0

Work on endorphins

Large releases of dopamine

Question 1

Explain the different ways drugs can work

Answer 1

They can increased levels of natural neurotransmitters

Increase of dopamine-remember this event

Opiates (and meth release dopamine)

Cocaine-blocks the reabsorption of dopamine and neroepinephrine

Mimic the activity of neurotransmitters-

Nicotine-acetylcholine

Alcohol-binds to the acetylcholine and serotonine receptors

Question 2

Explain the pathophysiology to tolerance (List the different ways tolerance can happen)

Answer 2

Increase in number of receptors-example large amounts of nicotine in the body will increase the amount of acetylcholine receptors-so when nicotine levels decrease the body exhibit symptoms of withdrawal

Increase the release of excitatory neurotransmitter’s-example alcohol trying to balance the system

Increase dopamine degrading enzyme

Depletion of neurotransmitters