additional thoughts Flashcards
(16 cards)
The human genome has about how many genes?
20 000
What are genetic polymorphisms?
sites in the genome that vary among different individuals, and usually refers to a genetic variant that occurs in 1% of the population
What is the exome?
portion of the genome that codes for protiens
Chromosomes consist of 2
-chromatin and histones
Epigenetic inheritance depends on ____
factors other than DNA
An epigenetic state can usually be ____
reversed
Interchromosomal interactions can be shown through ___ treatment
hormone
What is a topologically associated domain?
TAD - regions in a genome where DNA in that region interacts more strongly with other DNA in that region
RNA polymerase moves in the ________ direction
3-5
General transcription factors assemble at the _____ just upstream of the transcriptional start site to recruit and modify _____
pre initiation complex, RNA pol II
does peptide bond formation require energy?
no, spontaneous
RNA interference has potential for treating what?
Huntingtons
What is bromodeoxyuridine?
BrdU - thymidine analog that incorporates DNA of dividing cells
What is the main DNA polymerase in prokaryotes?
Pol III
DNA replication takes place in what phase of the cell cycle?
S
