additional thoughts Flashcards
The human genome has about how many genes?
20 000
What are genetic polymorphisms?
sites in the genome that vary among different individuals, and usually refers to a genetic variant that occurs in 1% of the population
What is the exome?
portion of the genome that codes for protiens
Chromosomes consist of 2
-chromatin and histones
Epigenetic inheritance depends on ____
factors other than DNA
An epigenetic state can usually be ____
reversed
Interchromosomal interactions can be shown through ___ treatment
hormone
What is a topologically associated domain?
TAD - regions in a genome where DNA in that region interacts more strongly with other DNA in that region
RNA polymerase moves in the ________ direction
3-5
General transcription factors assemble at the _____ just upstream of the transcriptional start site to recruit and modify _____
pre initiation complex, RNA pol II
does peptide bond formation require energy?
no, spontaneous
RNA interference has potential for treating what?
Huntingtons
What is bromodeoxyuridine?
BrdU - thymidine analog that incorporates DNA of dividing cells
What is the main DNA polymerase in prokaryotes?
Pol III
DNA replication takes place in what phase of the cell cycle?
S
