ADHD Flashcards

(38 cards)

1
Q

There’s a skepticism about ADHD and the Pharmaceutical industry, why?

A

Lot of money to be made in medication around ADHD
-> 2.5 billion $ spent on ADHD

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2
Q

How is ADHD real? (2)

A

(1) Prevalence similar worldwide
-> Use of mediation to treat ADHD 5x higher in N. America BUT prevalence is the same
(2) ADHD associated with marked impairment (pb with peers/school, mortality…)

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3
Q

ADHD: Categorical or Dimensional?

A

DSM treats ADHD as categorical but research suggests it’s dimensional

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4
Q

Assessment of ADHD (3)

A

(1) Rating scales and interviews: Parent/Teacher report (!!) critical for diagnosis
(2) Diagnostic interviews
(3) Symptom rating scales: Strong focus on OBSERVABLE signs of ADHD

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5
Q

Usually, we do NOT ask younger kids to self-report, why? (3)

A

(1) Children tend to underreport their own symptoms
(2) + Positive bias/Positive illusory bias (report higher self-esteem than warranted by behavior)
(3) + Quality of life rated better than others

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6
Q

What’s a famous semi-structured interview for ADHD?

A

Kiddie SADS
- Interview with people in the family
- Evaluates difficulty sustaining attention on tasks or play activities/remain seated…

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7
Q

What’s a famous rating scale for ADHD?

A

SNAP-IV ADHD rating scale
Might have a parent and a teacher fill them out.
-> 18 items = 18 symptoms of ADHD

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8
Q

How does the diagnosis of ADHD change if we use the ‘AND’ or ‘OR’ rule?

A

(1) If look at parent/ teacher alone, you see more predominantly diagnoses of EITHER PI and PH (less combined type and more PI/PH)
(2) When combined using the “or” rule -> many of those cases become combined

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9
Q

Sluggish Cognitive Tempo/Cognitive Disengagement Syndrome (CDS) correlation

A

High positive correlation with ADHD-PI
-> 50% of Inattentive ONLY, have this Cognitive Disengagement Syndrome

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9
Q

Cognitive Disengagement Syndrome: Proofs (6)

A

(1) Symptoms coherent among themselves (highly correlated w each other and other symptoms of ADHD)
(2) High internal reliability: Pple tend to respond to them in a similar way
(3) Reasonable test-retest reliability over short time periods
(4) Significant stability and invariance over long periods (2-9 years)
(5) Low-to-moderate relationships between parent and teacher ratings (similar to other disorders)
(6) Are evident cross-culturally

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9
Q

… of Inattentive ONLY, have the Cognitive Disengagement Syndrome

A

50%

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10
Q

Cultural difference and importance of ADHD (individualistic vs collectivistic)

A

If a culture value of group harmony (more collectivistic), ADHD might be way more problematic (vs individualistic society)

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11
Q

Symptom presentation of ADHD varies by gender (2)

A

(1) Community samples: boys more likely to be diagnosed w ALL subtypes of ADHD (but gap wider for ADHD-C & HI)
(2) Girls overrepresented in the Inattentive category
-> Interaction between expectation (gender socialization) and differences due to underlying factors

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12
Q

Developmental course of ADHD

A
  • Should be present from BIRTH (although no valid measure before age 3)
  • Beyond elementary school, outward hyperactivity might continue to decline slightly (but still higher than people without ADHD)
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13
Q

Long term outcome/Prognosis - ADHD

A

If symptoms last for a YEAR OR MORE in PRESCHOOL-AGE KIDS => significant warning for sustained challenge across time.

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14
Q

Previously thought that symptoms of ADHD resolved in adolescence: Is it true?

A

Not really:
1/3 of child diagnosed in childhood will continue to meet criteria throughout adulthood

15
Q

Adult Outcomes of ADHD (Klein et al., 2012)
- 207 boys recruited with hyperactiviy
- When the ADHD boys were 18, they recruited comparison participants (matched for age + parental occupation)
- Followed up with probands and comparisons when they were 41 years old
Results?

A

(1) But compared to comparison group, ADHD group had lower SES and lower IQ (diff might be inflated by that)
(2) ADHD pple LESS likely to:
- Finish high school
- Complete graduate degree
- Lower income
- More divorce
- More incarceration
- More deceased

16
Q

Etiology of ADHD

A

Mostly caused by genetics, but maintained and exacerbated by environmental influences
(1) ~75% heritability
(2) the other 25% -> environmental influences
=> E.g. maternal use of cigarets/alcohol during pregnancy… toxins/stressors increase risk of ADHD (not sure causal but association)

17
Q

Medication for ADHD (2)

A

Stimulants
- Dextroamphetamine (Dexedrine)
- Methylphenidate (Ritalin, Concerta)
Fast acting drugs: within minutes, clinical effects

18
Q

What does the ADHD medication do?

A

Increase activity in the prefrontal cortex
-> Increases dopamine: helps with inhibition

19
Q

ADHD medication: Side effects (5)

A
  • Reduced appetite
  • Weight loss
  • Slowing of growth
  • Difficulty falling asleep
  • Increased heart rate
20
Q

What are the cons of the ADHD medication? (4)

A

(1) 20% of children may NOT improve with medication use (non-responders)
(2) May not help academic performance, peer relationships, or family functioning in all kids
(3) Beneficial effects may not be maintained over time and will stop once medication is stopped
(4) Tolerance may also occur, in large % of cases leading to reduced efficacy over time at the same dosage

21
Q

Types of behavioral treatment (5)

A

(1) Parent management training
(2) Behavioral classroom management
(3) Behavioral peer interventions
Other:
(4) Cognitive interventions: Cognitive techniques that children can use to control attention and behavior (e.g., verbal self-instruction, problem solving)
(5) Organizational skills training – can help with impairment related to ADHD (e.g., school failure) - benefits in academic domain

22
Q

Parent Management Training def

A

Goal = Supporting caregivers managing challenging child behaviour & promoting positive behaviors
-> Slow approach to learning strategies; Very parent-focused
-> Relatively short program: 10-15 sessions.

23
Parent-focused program structure (4)
(1) Psychoeducation: Education about ADHD (2) Improve parent-child relationship: -> Positive Attention & Affirmation -> to increase behavior we wanna see -> Special time (10min a day) -> Parent thought and mood monitoring (3) Behavioural strategies: -> Behaviour charts & rewards for positive behaviour -> Routine and structure building -> Time-outs and privilege removal (4) Communication Strategies: -> Encouraging firm and assertive communication when necessary + Assertive imagery
24
Special time - characteristics (#)
(1) Emphasis on providing child with positive attention (2) Praise child for positive behaviours (3) Ignore minor misbehaviour (e.g., whining) -> 10 minutes a day (usually, child-led activity)
25
Evidence: Parent Training Programs
(1) OVERALL, meta-analyses and systematic reviews point to benefits for children AND for parents -> Significantly reduce ADHD symptoms in children -> Small to medium-positive effects on parent outcomes: Parent-child relationship quality, parent mental health, parenting sense of competence
26
Parent Training Programs: Disadvantages
Effects may NOT be sustained over time -> Moderate effect sizes at post-treatment, small effect sizes at follow up -> More follow up sessions may be beneficial
27
Other interventions (2)
(1) Cognitive interventions: Cognitive techniques that children can use to control attention and behavior (e.g., verbal self-instruction, problem solving) (2) Organizational skills training – can help with impairment related to ADHD (e.g., school failure) - benefits in academic domain
28
Multimodal Treatment of ADHD (MTA) Study -> Explain the experiment (3)
- Big RCT - 6 sites among US - Age 7 to 9 (n=579), 80% male - ADHD-C diagnosis (parent/teacher report) - Randomly assigned to 4 groups => Medication only => Psychosocial only (parent training + educational intervention + summer program) => Combination treatment => Community treatment as usual (TAU)
29
Multimodal Treatment of ADHD (MTA) Study -> Explain the 3 main objectives
(1) Compare long-term medication vs behavioral treatments for ADHD (2) Determine if there are additional benefits if meds + behavioral treatment are combined (3) Compare systematic administration of treatment vs treatment delivered in community settings
30
Multimodal Treatment of ADHD (MTA) Study: Results (2)
(1) Core symptoms of ADHD: (note - everyone got down/no huge diff) - 1-combination, 2-medication, 3- psychosocial, 4-TAU (2) Parent-child conflict: 1-combination, 2-psychosocial, 3-medication, 4-TAU
31
Several of follow-ups with MTA sample: => 2 years post-intervention (youth were ~10y.o) to 16 years post-baseline (when youth were ~25 on average) -- Results? (3)
(1) 2 years post-baseline: less than 50% have diagnosis (2) Overall very little full and sustained recovery (15-20%still subclinical; about 10% fully recovered) (3) Many people fluctuate in symptoms and impairment X time => Even though benefits from intervention, pple tend to have longer term symptoms and impairments
32
Treatment Studies (Chronis-Tuscano et al., 2012) - Explain the experiment
- Targeting maternal depressive symptoms and parenting children with ADHD - Randomized in 2 groups: (1) Behavioural parent training (2) Integrated intervention (added relaxation techniques...)
33
Treatment Studies (Chronis-Tuscano et al., 2012) - Results?
(1) Integrated Intervention: small to moderate impacts compared to behavioral parent training (2) However, effect wasn’t sustained (3) At later follow ups, Parent training group had better “positive parenting” vs integrated intervention group => Integrated intervention – positive impacts post-treatment => Parent training – impacts on “positive parenting” at later follow ups
34
ADHD: deficit in attentional capacity, sustained attention or selective attention?
SUSTAINED attention poorer (core feature) -> NO deficit in attentional capacity
35
Are ADHD kid less intelligent?
No, BUT -> Score 5-9 points lower on IQ test -> low IQ can be direct effect of ADHD on test-taking behavior
36
Brain differences in ADHD
Differences in the frontostriatal circuitry of the brain (basal ganglia, PFC) => ADHD = smaller right PFC, structural diff in basal ganglia, smaller right cerebral volume…