ADNEXA/OVARIES Flashcards

(163 cards)

1
Q

Diffuse disease of the female pelvic cavity

A

PID
ENDOMETRIOSIS

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2
Q

Most commonlyPID caused by
Uncommonly reason

A

Sexual disease
Genera
Chlamydia
Un. Ruptured appendix peritonitis

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3
Q

Early stage of endometriosis and PID may mimic

A

Functional bowel disease

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4
Q

Pelvic infection PID:

A

Endemetritis
Salpingitis
Hydrosalpinx
Pyosalpinx
Periovarian inflammation
Tubo ovarian complex
Tubo ovarian abscess

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5
Q

Parametritis

A

Infection found in uterine serosa and broad ligaments

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6
Q

Oophoritis

A

Ovary infection

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7
Q

Most common location

A

Oviduct
Salpingitis

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8
Q

Us in chronic Pid

A

Dilated fallopian tubes
Hydrosalpinx
Pyosalpinx
Abscess
Complex fluid intraperitoneal

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9
Q

PID clinical symptoms

A

Large palpable bilateral complex mass
Ovary separate from mass
free fluid in cul-de-sac
Doppler increase vasicularity
Infertility
Endometritis
Intensive pervic pain and tenderness described as dull aching
constant vaginal discharge
Fever
Pain in right upper abdomen
Mistral irregular bleeding
Painfull intercourse

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10
Q

Fitz-hugh- Curtis syndrome

A

Perihepatic inflammation
Along liver margin
Hypoechoic rim between liver and
Adjacent rib

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11
Q

PID lab test

A

I WBC
Caused by chlamydia
Way be asymptomatic

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12
Q

Differential consideration

A

Hematoma
Dermoid cyst
Ovarian neoplasm
Endometritis

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13
Q

Us if endometritis
Periovarian inflammation

A

Thickening or fluid endometrium
Periviovarian inflammation
Enlarged ovaries with multiple cysts
Indistinct margin

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14
Q

Us salpingitis
Clinical

A

Nodular thickening
Irregularity of tube with diverticle
Dilated tube
Tortuous

Low-grade fever
Asymptomatic
Pelvis fullness

Unilateral or bilateral

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15
Q

Us pyosalpinx or
Hydrosalpinx

A

Fluid-filled
Regular fallopian tide
With or without echo

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16
Q

Us
Tube- ovarian abscess

A

Complex mass
With septarian
Irregular margins
Internal echoes
Usually in Incul-de-sac

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17
Q

Acute salpangitis

A

The tube is enlarged
Distended with echoes pus appears
Thickwall

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18
Q

Hydrosalpinx
Reasons

A

PID
Endomeíritis
Post operative adhesions

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19
Q

Hydrosalpinx
Clinical
Us

A

A symptomatic
Pelvic fullness
Law grade fever

Wall thin ia dilatio
Multi cystic or fusi form mass
Dilated tube from fundus of uterus
Bilateral
Ampulary more dilated then interstitial
Pointed beak at swan end of tube near isthmus

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20
Q

Peritoneal psedocyst

A

With hemorrhagic mesotherial cyst appearance
Right lower pain in some patient
Fluid filled mass and separations in cul-de-sac

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21
Q

Tube-ovarian
Abscess
Complex

A

Adhesive
Edemarous
Inflamedserosa
May adhere ovary
And other peritoneal surfaces
Distort anatomy
Periovarian adhesion
Ovary cannon be separated from dilated tube
Tube - ovarian complex
Response to -o
Sono guidance for drainage

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22
Q

Peritonitis
Inflammation of peritoneum
Pelvic peritonitis

A

If infection spreads to involve bladder
Ureter
Bowel
Adnexal area

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23
Q

US in peritonitis

A

.gas forming bubbles
Located areas of fluid within pelvis
Parabolic gutters
Mesentric reflections
Evaluation space btw right kidney and liver
Left kicky spleen

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24
Q

Endemetritis division

A

Obstetric. Immediate Post partum
NONObstetric _PID or IU

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25
Most common cause E of fever in Post partum
'endometritis
26
Normal thickness of endemiritis If more than
20mm More than Endometritis hemorrhage Retained products of pregnancy Risk increases Prom Retained clot Prolonged labor
27
Endometriosis
Presence of functionalendometrial tissue in abnormal locations Anywhere Especially more dependent Parts of pelvic Cut de sac
28
Clinical finding endomeírisis
Severe diysmenorrhea Chronic pelvic pain Adhesion Bleeding Dysparenuia during sexual intercourse
29
Types of endometriosis
Internal and External
30
Internal endometriosis
Within the uterus Adenomyosis
31
External endometriosis
Outside the uterus Pouch of Douglas Surface of ovaries Fallopian tube Uterus broad ligaments Rectovaginal septum
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More common form of endometriosis
External or indirect
33
Internal or direct form of endometriosis clinical
Adenomyosis Invading the uterin body Invading junction al zone and myometrium Heavy menstrul bleeding and uterin e enlargement C
34
Adenomyosis most common
Women had uterin surgery
35
Us endometriosis
Uterin bulbous Myometrial cysts Border between endometrium and myometrium is in distinct BLUURED BORDER appearance more common in posterior of uterus MRI more than US IN distinct
36
External or localized form
Discrete mass Endometrioma Or chocolate cyst Asymptomatic May enlarged Surgical emergency By rupture Causing ovary twisted Common site is ovaries chocolate cyst enlarge ovaries
37
External form in US
Rarely detected Unless focal mass Endometrioma present Endometriomas may uni or bilateral ovarian mass Ranging from anechoic To solid depending on amount of blood Ovaries adhere to pos uterine or in culled sac Difficult to define May be cystic mass be disseminated cancer or pelvic infection
38
More common form of endometriosis
Diffuse external endometriosis
39
Ground glass appearance
Endometrioma and mass in the ovaries fills with blood
40
Ovaries places
If uterus in the midline lateral or posterolateral Uterus in one side of midline ipsilateral ovary superior to uterine fundus In retroverted ovaries lateral and superior Enlarge ed uterus ovaries more superior and laterally Hysterectomy ovaries in midline superior to vaginal cuff Or in high in pelvis or in curl de sac TV if ovaries superiorly or extremely latterly can not be seen
41
Cumulus oophorus
As eccentrically located cyst like 1 mm internal mural protrusion Mature follicle and ovulation
42
Crenulated Scalloped follicles
Occasionally follicles decrease in size and develops a wall
43
Follicular cyst
Develops if fluid in non dominant follicles not reabsorbed Like simple cyst Dominant follicles disappear after ruptured at ovulation
44
Free fluid in the culled sac
Commonly seen in. Lute all phase after ovulation
45
Following ovulation in luteal phase
Mature corpus luteim Develops and may be identified in US as small hypoechoic or isoechoic structure periphery within the ovary May appear irregular with echo genie crenulated wall contain low level echoes
46
Less frequent appearance of corpus
RING OF FIRE In Doppler around wall of the isoechoic corpus That the same as ectopic pregnancy
47
Multiple small punctate Echo genie foci commonly seen in normal ovary
Very small 1 2 mm Periphery no shadowing Multiple
48
Abnormal volum of the ovaries
22 ml in menstration mean 9;8 ml +- 5.8 In pst menopause more than 8 ml abnormal If one side is twice of another
49
Majority of ovarian masses
Simple cysts benign If in post menopause seen more than 5 cm with septation and solid echoes surgery recommended
50
Common cystic or complex ovarian mass
Follicular cyst Capos luteum Cystic teratoma Para ovarian cyst Hydrosalpinx Endometrioma Hemorrhagic cyst
51
Complex mass or cyst
Any simple cyst that hemorrhages as involuted برگشتن به حالت اولیه خودش
52
Reproductive age complex mass classic differential
Adnexal mass Ectopic Endometrioma Endometriosis PID dermoid and other benign tumours Cystadenoma Granulosa cell Tumours or Tubo ovarian abscess
53
Most common solid tumours of ovaries
Serous types Cyst Adenoma Cyst adeno carcinoma
54
Solid tumours
More complex the Tubo more more likely to be malignant Especially with ascites
55
When solid mass found identify connections with uterus
To deferentiate ovarian lesion from pedunculated uterine fibroid Color Doppler to see the vascular pedicle between uterus and mass
56
Common solid mass arising ovaries
Solid teratoma Adenocarcinoma Arrhenoblastoma Fibroma Dysgerminoma Torsion
57
Doppler of the ovary
Suspected cystic lesion In differentiating potential cyst from adjustment vascular iliac artery Pulse Doppler for Adnexal branch uterin artery Ovarian artery Intramural flow To determine resistive index
58
Doppler of ovaries time
Normal men’s in first 10 days of cycle To avoids confusion with normal changes in intraovarian blood flow because high diastolic flow occurs in luteal phase
59
Value for RI AND PI IN Doppler
RI > 0.4 PI > 1
60
Sign for malignancy
Intramural vessels Low resistance flow Absence of normal diastolic notch in DOPPLER
61
Abnormal waveform can be seen in
Inflammatory masses Metabolically active masses ectopic pregnancy corpus luteum cysts RI is not the sensitive indicator of malignancy
62
Diastolic notch in early diastolic
Sign of benign disease
63
Functional ovarian cysts
Follicular Corpus luteum Hemorrhagic Theca lutein cysts
64
Follicular cyst
When dominant follicles does not succeed in ovulating and remains active Unilateral Thin wallled translucent watery fluid 1- 8 cm Disappear or rupture Simple cyst
65
Corpus luteum cyst
From hemorrhage whitin mature corpus luteum that persisted Filed with blood 1-10 cm May accompany the intrauterine pregnancy May mimic ectopic Rupture cyst type lesion internal echo Increase color
66
2-hemorrhage cyst
Internal hemorrhage can occur in follicular cyst Or corpus luteual cyst Acute onset of the pelvic pain Appearance: Hemorrhagic cyst with Retracted blood clot showing reticular inner or cobweb or fishnet appearance Indicating hemolysis of the blood
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Diffuse low level echoes may be seen
In Endometriomas Chocolate chips and ground glass
68
3- Theca lutein cyst
Large bilateral multiloculated cyst With high level of bhcg In 30% of trophoblastic molar enlarged uterus filled with grapelike clusters Nausea vometing In US, multilocular cyst in both ovaries
69
Ovarian hyper stimulation syndrome
Mild Severe Severe pelvic pain Ascites Abdominal distension Pleural effusion Ovaries more than 10 cm Numerous large thin walled cyst Ovaries no more in pelvic cavity and become abdomen organ
70
Polycystic ovarian syndrome
Include stein levanthal syndrome an endocrine disorder with chronic an ovulation Bilaterally enlarge polycystic ovary Clinical amenorrhea Obesity Hirsutism Infertility In US Multiple tiny cyst around periphery of ovary may be normal or enlarged ovary Imbalance in FSH LH. Abnormal estrogen and progesterone characteristics finding in poly Ovaries are rounded increase number of follicles
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characteristics finding in polycystic
Imbalance in FSH LH. Abnormal estrogen and endrogen Elevated LH / FSH ratio
72
Follow up polycystic patients
Unopposed esterogenic hyperplasia and endometrial carcinoma occurs in significant proportion PCOS common cause of infertility and early pregnancy loss
73
Polycystic ovation appearance
Enlarge ovary with string of pearls enlarged follicles prominent follicles around peripheral ovary
74
Peritoneal inclusion cyst
When adhesion trap peritoneal fluid around ovaries Resulting in large Adnexal mass Pelvic pain pelvic mass
75
Para ovarian cyst
Simple Wolfian duct remnant Can bleed undergo torsion In broad ligament Asymptomatic Simple cyst adjuscent to ovary May completely fill the Adnexal region
76
Endometriosis
Endometrioma chocolate cyst
77
Ovarian torsion
3% of gynaecology operative emergencies Partial or complete rotation of ovarian pedi ul on its axis Enlarge edematose ovary more than 4 cm Hypoechic mass Free fluid in pelvic Absent of blood flow to TOR sed ovary Result in Edelman Loss of arterial perfusion Infarction of the ovary Involves ovary and fallopian tube
78
Torsion of normal ovary usually in
In children and younger female with mobile Adnexa pre-existing ovarian cysts or mass Or pregnancy More often in the right side can mimic appendicitis
79
Abnormal ovaries suggest malignancy defined as
Enlarged echogenic ovaries
80
1) ovarian carcinoma
Absent of symptoms in early stage Not detected until advanced Having spread beyond capsule but still within pelvic stage ll In to abdomen stage lll Normal to slightly enlarge firm irregular ovaries to pelvic mass Differentials Endometriosis Hemorrhagic ovarian cyst Ovarian torsion PID Benign ovarian neoplasm Increase age increase malignant Less than 5 cm benign More than 10 cm malignant
81
Strongest risk factor for ovarian carcinoma
Family history of ovarian and breast cancer Other Nulliparity Infertility Uninterrupted ovulation Late menopause
82
Epithelial tumours
80 to 90% malignancy 65% to 75% ovarian neoplasm Surface epithelial stromal tumours Arise from surface epithelium cover ovary and underlying stroma
83
Most common types are
Serous and mucinus tumours Serous epithelial tumours are common
84
Mucinous cystadenoma 20% to 25%
Benign ovarian Mucinous cystadenocarcinoma 5%to 10% malignant ovarian neoplasm
85
Serous cystadenoma more common in malignancy cystadeno carcinoma
Second most common benign tumour of the ovary after dermoid 20% to 25% of all benign ovarian tumours Serous cyst adeno carcinoma 60 to 80% ovarian carcinoma
86
Adenoma
Benign or low malignancy potential
87
Cyst add to term
Lesion cystic Malignant form adenocarcinoma Fibroma more than 50% of tumour fibrous
88
2-1 Mucinous cystadenoma
Type of epithelial tumour lined by Mucinous elements 20% to 25% benign ovarian neoplasm Mucinous cystadenocarcinoma malignant
89
Cystadenocarcinoma marked sign
Septal nodularity Large sized and septation
90
Mucynous cystadenomas
Benign large sized septation are characteristics in women 13 to 45 80% to 85% is benign Very large 15-30 cm
91
Sonographic findings
• In 75% of patients with mucinous tumors, ultrasound examination shows simple or septate thin-walled multilocular cysts • Contain internal echoes with compartments differing in echogenicity caused by mucoid material in dependent portions
92
Mucinus cyst-adenoma
• Unusually large (15 to 30 cm) • Most common cystic tumor • Usually, unilateral • Cyst filled with sticky, gelatin-like material • Multilocular cystic spaces • Benign type more common than malignant • Clinical: pressure, pain, increased abdominal girth • Sonographic findings: simple or septate thin-walled multilocular cysts
93
Mucinous cystadenocarcinoma
• Most frequently occurs in women 40 to 70 years old • Accounts for 5% to 10% of all primary malignant ovarian neoplasms • 15% to 20% bilateral when malignant
94
Psedumixoma peritoneum
• 10% occur in menopausal women • Can also become very large and more likely than benign form to rupture • If tumor ruptures, associated with pseudomyxoma peritoneum • Causes loculated ascites with mass effect
95
In us mucinous
Sonographic findings • Malignant cysts tend to have thick, irregular walls and septations with papillary projections and echogenic material. •Generally, have sonographic appearance similar to serous cystadenocarcinomas
96
Mucinous cystadenocarcinoma
• Bilateral • May occur in menopausal women (10%) • Large, likely to rupture-ascites • Clinical: pelvic pressure; pain when ruptured • Sonographic findings: ascites appears as hypochoic fluid with bright punctate echoes; thick, irregular walls and septations
97
Serous cyst adenoma
• Second most common benign tumor of ovary (after dermoid cyst) • Represents 20% to 25% of all benign ovarian neoplasms • Is usually unilateral; 20% are bilateral
98
Serous cyst adenocarcinoma
G, H, and I are images in a single patient with a serous cystadenocarcinoma. Extensive nodularity shows vascularity confirming the morphologic suspicion of a malignant mass. There is high diastolic flow resulting in a low resistive index.
99
Serous cyst adenoma
Sonographic findings • Usually, unilocular or multilocular with thin septations • Smaller than mucinous cysts (up to 20 cm); borders irregular with loss of capsular definition • Multilocular cysts contain small amount of solid tissue in chambers of varying size with occasional internal septum or mural nodules
100
Serous cyst adeno carcinoma
• External papillary mass adhesions and infection lead to bilateral involvement. • Loss of capsular definition and tumor fixation; calcifications Peritoneal implants; ascites; metastases to omentum, lymph nodes, liver, and lungs • Clinical: pelvic fullness, bloating • Sonographic findings: cystic structure with septations and/or papillary projections; internal and external papillomas usually present
101
Germ cell tumours
• Account for 15% to 20% of ovarian neoplasms, with approximately 95% being benign cystic teratomas • Besides teratomas, germ cell tumors include dysgerminoma, embryonal cell carcinoma, choriocarcinoma, and transdermal sinus tumor.
102
Associated with elevated AFP and hcg levels
• Often occur as mixed tumors with elements of two or three varieties of germ cell layers • Associated with elevated alpha-fetoprotein (AFP) and hCG levels
103
Teratoma mature benign form
Teratoma: Dermoid Tumors • Size ranges from small to 40 cm • Unilateral, round to oval mass • Contains fatty, sebaceous material, hair, cartilage, bone, teeth • Clinical: asymptomatic to abdominal pain, enlargement and pressure; pedunculated; subject to torsion • Sonographic findings: cystic/complex/solid mass; echogenic components; acoustic
104
Dermoid plug
2) Cystic mass with very echogenic nodule along mural wall representing "dermoid plug"
105
TERATOMAS IN US
Sonography may demonstrate one of several patterns: 1) Completely cystic mass 2) Cystic mass with very echogenic nodule along mural wall representing "dermoid plug" 3) Fat-fluid level 4) High-amplitude echoes with shadowing (e.g., teeth or bone) 5) Complex mass with internal septations
106
IMATURE TERATOMAS MALIGNANT FORM
• Immature teratomas uncommon; occur in girls and young women 10 to 20 years of age • Rapidly growing, solid malignant tumors with many tiny cysts • AFP elevated in 50% of patients • Unilateral and small in size; may grow to larger dimension
107
The tip of the ice berg sign
Immature teratoma because of shadowing you cannot say how deep it is the posterior margins is not appreciated
108
Dermoid mesh
Hyper echo IVC lines corresponding hair in dermoid tumours TERATOMAS small hyperechoic floating lines and dots
109
Dermoid plug or Rokitansky nodule
Hyperexhoic nodule situated near the wall of the cyst with posterior shadowing
110
Mobile spherules
Image (5). A well-defined large complex adnexal mass lesion, with multiple large floating / mobile echogenic spherical structures (named mobile spherules) in benign cystic TERATOMAS
111
Benign cystic teratoma dermoid cyst appearance
Image (6). A well-defined large cystic adnexal mass lesion, with fat-fluid level (non-dependent lower density hyperechoic fat floating over dependent higher density hypochoic fluid).
112
* most common ovarian neoplasms seen in pregnancy.
Dysgerminoma and serous cystadenoma are two
113
Dysgerminoma
Dysgerminoma • Rare malignant germ cell tumor bilateral in 15% of cases • Mass constitutes 1% to 2% of primary ovarian
114
Dysgerminoma
• Entirely solid ovarian mass in woman <30 years of age usually dysgerminoma
115
Endodermal Sinus Tumor
• Endodermal sinus tumors rare rapidly growing tumors also called yolk sac tumors • Usually occurs in women <20 years of age; is almost always unilateral • Increased serum AFP may be seen.
116
Yolk sac tumor
Endodermal Sinus Tumor
117
Endodermal Sinus Tumor
• Endodermal sinus tumor has poor prognosis. • Second most common malignant ovarian germ cell neoplasm after dysgerminoma •Sonographic appearance similar to dysgerminoma
118
•Sonographic appearance similar to dysgerminoma
Endodermal Sinus Tumor
119
• Second most common malignant ovarian germ cell neoplasm after dysgerminoma
Endodermal Sinus Tumor
120
• Sex cord-stromal tumors Stromal بستر
• Sex cord-stromal tumors typically solid adnexal masses that arise from sex cords of embryonic gonadal and/or ovarian stroma • Includes granulosa cell tumor, thecoma, fibroma, and Sertoli-Leydig cell tumors (androblastoma) • Accounts for 5% to 10% of all ovarian neoplasms and 2% of all ovarian malignancies
121
Fibroma and Thecoma
• Both fibroma and thecoma tumors arise from ovarian stroma; are pathologically similar • Tumors with abundance of thecal cells called thecomas, and those with abundance of fibrous tissue called fibromas • Thecomas usually benign and unilateral, comprising 1% of all ovarian neoplasms; 70% occur in postmenopausal women • Frequently show signs of estrogen production
122
70% occur in postmenopausal women
Fibroma and Thecoma
123
Fibroma
• Comprise 4% of ovarian neoplasms • Rarely associated with estrogen production • Clinical signs include lack of symptoms if tumor small • If large, increasing pressure and pain apparent • Ascites has been reported in up to 50% of patients with fibromas >5 cm in diameter
124
Ascites has been reported in up to 50% of patients
with fibromas >5 cm in diameter
125
•Meigs syndrome
Meigs syndrome is defined as the triad of benign ovarian tumor with ascites and pleural effusion that resolves after resection of the tumor.
126
Fibroma
• Associated ascites along with pleural effusion • Referred to as Meigs syndrome; occurs in 1% to 3% of patients with fibroma • Not specific; it can occur with other ovarian neoplasms as well • Found in postmenopausal women
127
the majority of the benign tumors seen in Meigs syndrome.
Ovarian fibromas constitute the majority of the benign tumors seen in Meigs syndrome.
128
Granulosa Cell Tumor clinical
• Clinical symptoms of estrogen production may include precocious puberty or vaginal bleeding and full breasts. • Pain, pressure, fullness may also be present. • May twist on itself to cause torsion or rupture, leading to Meigs syndrome • Malignant transformation rare, but when it occurs, lesion spreads via lymphatics and bloodstream
129
Granulosa Cell Tumor
• Feminizing neoplasm composed of cells resembling graafian follicle • Most common hormone-active estrogenic tumor of ovary • More common after menopause (50%) • Also seen in reproductive ages (45%) and in adolescence (5%)
130
• Most common hormone-active estrogenic tumor of ovary
Granulosa Cell Tumor
131
• More common after menopause (50%)
Granulosa Cell Tumor
132
Granulosa Cell Tumor • Clinical symptoms of estrogen production may include
precocious puberty or vaginal bleeding and full breasts. • Pain, pressure, fullness may also be present. • Maystwist on itself to cause torsion or rupture, leading to Meigs syndrome • Malignant transformation rare, but when it occurs, lesion spreads via lymphatics and bloodstream
133
Granulosa Cell Tumor in US
Sonographic findings • Variable appearance • Mass without torsion • Similar to endometrioma or cystadenoma, with low-level homogeneous echoes • If torsion occurs, multilocular cyst containing blood or fluid seen • Solid masses may have echogenicity similar to uterine fibroids.
134
Metastatic Disease
Metastatic Disease • Ovaries more involved with metastatic disease than any other pelvic organ • Metastases often mimic appearance of advanced stage II to III primary ovarian cancer. • Approximatelv 5% to 10% of ovarian nanni. metastatic in a
135
• Krukenberg tumors
• Krukenberg tumors "drop" metastases to ovaries from GI tract, primarily from stomach, but also from biliary tract, gallbladder, pancreas.
136
Sonographic findings • Metastatic disease to ovaries
Sonographic findings • Metastatic disease to ovaries frequently bilateral and often associated with ascites • Metastases usually completely solid or solid with "moth-eaten" cystic pattern that occurs when nectotic
137
moth-eaten" cystic pattern
Metastases usually completely solid or solid with "moth-eaten" cystic pattern that occurs when nectotic بید گاز زده
138
• Lymphoma
‏nvolving ovary usually diffuse and disseminated and frequently bilateral ‏• Sonographically, mass appears as solid hypochoic tumor similar to lymphoma elsewhere body.
139
Carcinoma of the Fallopian Tube
• Least common (<1%) of all gynecologic malignancies • Adenocarcinoma most common histological finding • Occurs most frequently in postmenopausal women with pain, vaginal bleeding, pelvic mass • Usually involves distal end; may involve entire length of tube
140
• Least common (<1%) of all gynecologic malignancies
Carcinoma of the Fallopian Tube
141
Carcinoma of the Fallopian Tube most in
• Occurs most frequently in postmenopausal women with pain, vaginal bleeding, pelvic mass
142
Carcinoma of the Fallopian Tube in US
Sonographic findings • Appears as sausage-shaped, complex mass, with cystic and solid components often with papillary projections • Clinical and sonographic findings similar to those of ovarian carcinoma
143
• Appears as sausage-shaped, complex mass, with cystic and solid components often with papillary projections
Carcinoma of the Fallopian Tube in US
144
• The differential considerations of a solid-appearing adnexal mass include
pedunculated fibroid, dermoid, fibroma, the-coma, granulosa cell tumor, Brenner tumor ( a solid abnormal growth on the ovary most benign most often in women after menopause), and metastasis. Tubo-ovarian abscess, ovarian torsion, hemorrhagic cysts, and ectopic pregnancy also may appear solid. • Pulsed Doppler interrogation of the adnexal branch of the uterine artery, the ovarian artery, or intratumoral flow is performed to determine the resistive index or pulsatility index.
145
Theca-lutein cysts
are the largest of the functional cysts and appear as very large, bilateral, multiloculated cystic masses. They are associated with high levels of human chorionic gonadotropin and are seen most frequently in association with gestational trophoblastic disease.
146
Omental cysts tend to be higher in the abdomen, and urachal cysts are midline in the anterior abdominal wall above the bladder
Omental cysts
147
Germ cell tumors include
teratomas, dysgerminoma, embryonal cell carcinoma ( type of testicular cancer) ( , choriocarcinoma, and transdermal sinus tumor.
148
Common Cystic or Homogenous Ovarian Masses
• Follicular cyst • Corpus luteum cyst of pregnancy • Cystic teratoma • Paraovarian cyst • Hydrosalpinx • Endometrioma (low-level echoes) • Hemorrhagic cyst • Cystadenoma • Dermoid cyst • Tubo-ovarian abscess • Ectopic pregnancy • Granulosa cell tumor
149
Ovarian Remnant Syndrome
Ovarian Remnant Syndrome. Infrequently, a cystic mass may be seen in a patient who has a history of bilateral oopho-rectomy. This usually results in a technically difficult surgery (because of adhesions), in which a small amount of residual ovarian tissue has been unintentionally left behind. The residual ovarian tissue can become functional and produce cysts with a thin rim of ovarian tissue in the wall.
150
Fluid Collections in Adhesions
. Fluid collections in adhesions can create cystic structures of odd shapes throughout the abdomen. Omental cysts tend to be higher in the abdo-men, and urachal cysts are midline in the anterior abdominal wall peritoneum above the bladder. Any tumor may have cystic elements, and the sonographer should demonstrate if the tumor is a simple cyst or a complex mass.
151
benign Cysts in Fetuses and Adolescents.
Small simple cysts (1 to 7 mm) normally occur in fetuses and newborn girls because of stimulation by maternal hormones. In pre-menarchal girls, small follicles (less than 9 mm) are common. Larger cysts also are seen in otherwise healthy premenarchal gis. These may be followed closely if they are regressing, as jong as the child's growth and development appear normal. Occasionally, ovarian cysts produce symptoms of precocious puberty in young girls. These may arise spontaneously or in association with other hormonal derangements.
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Other epithelial tumors
Less common varieties of epithelial tumors are endometrioid, clear cell, Brenner (transitional cell), and undifferentiated carci-noma. Endometrioid tumors are nearly all malignant and are the second most common epithelial malignancy. Approximately 25% to 30% are bilateral and occur most frequently postmeno-pausal; peak age ranges from 50 to 60 years. Clear cell tumors are considered to be of müllerian duct origin and a variant of the endometrioid carcinoma. Clear cell tumors are nearly always malignant and are bilateral about 20% of the time. Peak age ranges from 50 to 70 years. Transitional cell tumor, also known as Brenner tumor, is uncommon. The Brenner tumor is found in 1.5% to 2.5% of patients; peak age ranges from 40 to 70 years. It is nearly always benign and 6% to 7% are bilateral; 30% are associated with cystic neoplasms in the ipsilateral ovary. • Sonographic Findings. These types of epithelial tumors cannot be distinguished sonographically; however, they are more frequently found unilaterally. They are usually small and present as a nonspecific, complex, predominantly cystic mass. Occasionally the tumor may contain hemorrhage or necrosis. The Brenner tumors are hypochoic, solid masses that may contain calcifications in the outer wall. They are composed of dense fibrous stroma and appear similar to ovarian fibromas and thecomas.
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Epithelial tumors
Serous and mucinous Serous cystadenoma Serous cystadenocarcinoma Mucinous cystadenocarcinoma Mucinous cystadenocarcinoma Other epithelial tumors
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Germ cell tumors
Teratoma Immature and mature teratoma Dysgerminoma Endodermis sinus tumor
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Stromal tumors
Fibroma Thecoma Granulosa Sertoli leydig cell tumors Arrhenoblastoma
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Sertoli-Leydig Cell Tumor
Sertoli-Leydig cell tumors (also called androblastomas) are rare. They generally occur in women under 30 years and constitute less than 0.5% of ovarian neoplasms. Almost all are unilateral, and malignancy occurs in 10% to 20% of these tumors. Clinically, symptoms of virilization occur in about 30% of patients. Occasionally, these tumors may be associated with estrogen production. Sonographic Findings. Sonographically, the tumor usually appears as a solid hypochoic mass.
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Arrhenoblastoma
Arrhenoblastoma Arrhenoblastoma is a masculinizing ovarian tumor that occurs in females 15 to 65 years of age, with a peak incidence at 25 to 45 years. Clinical features are the same as for other pelvic masses, with the addition of amenorrhea and infertility. This mass may undergo malignant transformation in 22% of patients. • Sonographic Findings. The tumor is a solid mass with cystic components; it is lobulated and well encapsulated. In
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Cyst Adenoma
449. All of the following are solid tumors except: A. Thecoma B. Fibroma C. Brenner's tumor D. Cystadenoma E. Teratoma
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B. Cystic and ovarian in origin
Most adnexal masses are: A. Cystic, ovarian in origin, and malignant B. Cystic and ovarian in origin C. Ovarian in origin and malignant D. Cystic and malignant E. None of the above
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Granulosa cell tumors may be discovered in patients
Benign and estrogenic. Granulosa cell tumors may be discovered in patients of all ages, including children. Smatiy are seen in posimenopausal parients. They are usually benign but do on malignant potential. These estrogenic hmors secrete estrogen, causing pander female characteristics thai present as precocious puberty in children and seas veginal bleding and breast dysplasia in ihe posimenopausal patient. 18. E. Leiomyoma.
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€ 458. A 52-year-old female presents as postmenopausal for 5 years, G-4-PA. Her uterus is enlarged upon palpation and is irregular in contour. You suspect: A. Endomet: ial cancer B. Adenomyosis C. Endometriosis D. Hydatidiform mole E. Leiomyoma
E
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Arrhenoblastoma
459. B. Arrhenoblastoma. Arrhenoblaslomas are androgenic tumors that secrete lestosterone, causing secondary male characteristics. Female patients present with a masculine stature and male hair growth patterns on the face, abdomen, and upper thighs. After removal, female characteristics should return.
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Sex cord germ cell stromal tumors
• Includes granulosa cell tumor, thecoma, fibroma, and Sertoli-Leydig cell tumors (androblastoma)