Adolescent Health Flashcards

(54 cards)

1
Q

Criteria for hosp assessment in anorexia

A
  • rapid weight loss
  • BMI < 15
  • bradycardic HR <40
  • prolonged QTc > 450
  • electrolytes Na <130 or K < 3
  • postural hypotension
  • SUSS < 2
  • core body temp < 35
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2
Q

Cortisol in anorexia

A

High

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3
Q

Thyroid function in anorexia

A

low or normal T4

low T3

normal TSH

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4
Q

LH and FSH in anorexia

A

Low

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5
Q

GH in anorexia

A

Raised

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6
Q

GnRH in anorexia

A

Low

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7
Q

Last areas of the brain to mature

A

Superior temporal cortex & dorsal prefrontal cortex

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8
Q

Subcortical grey or white matter is involved in decision making?

A

Grey matter

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9
Q

What is the nucleus accumbens

A

Area of the brain associated with reward, gratification, motivation and fortification of behaviours

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10
Q

Major excitatory neurotransmitter

A

Glutamate

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11
Q

Major inhibitory neurotransmitter

A

GABA

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12
Q

Secondary syphilis symptoms

A

painless rash on palms and soles

viral type illness

swollen lymph nodes

white patches in mouth

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13
Q

Ix for syphilis

A

DARK field micropscpy

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14
Q

Rx syphilis

A

IM benpen

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15
Q

Rx gonorrhoea

A
  1. IM ceftriazone or cefixime
  2. azithromycin
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16
Q

What drugs is gonorrhoea highly resistant to

A

tetracyclines
penicillins
quinolones

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17
Q

IX chlamydia

A

NAAT testing

Female - vulvovaginal swab
Male - first catch urine

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18
Q

Rx chlamydia

A

Doxycycline or single dose azithromycin

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19
Q

Organism causing BV

A

Gardnerella vaginalis

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20
Q

How does metronidazole work in BV

A

inhibits bacterial nucleic acid synthesis by disrupting DNA

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21
Q

normal vaginal flora

A

gardnerella vaginalis
haemophilus influenzae

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22
Q

Rx scabies

A

Permethrin - topical insecticide

23
Q

Rx public lice

24
Q

What type of virus is HSV

A

double stranded DNA

25
Most common route of transmission for HIV
unprotected anal or vaginal sex with an infected individual
26
Ix of a neonate with possible HIV
HIV RNA PCR or DNA PCR Check at 24-48h, then 6w, then 3-4 months of age
27
Ix of a child with possible HIV
HIV antibodies
28
What constitutes a positive HIV diagnosis in a child
HIV antibodies are +ve after 18m in a child born to an infected mother HIV antibodies are +Ve at any age in a child born to an infected mother
29
Rx of an infant born to an HIV +ve mother
Start ART ideally within 12h but within 72h Low risk - zidovudine for 4w High risk - combination ART zidovudine/lamivudine/nevirapine
30
Rx of an HIV +ve child
start combination ART 2x NRTI + INI (or) NNRTI (or) PI
31
NRTIs
zidovudine lamivudine tenofovir abacavir emtricitabine
32
NNRTIs
nevirapine etravirine efavirenz rilpivirine
33
PIs
atazanavir darunavir fosamprenavir ritonavir indinavir
34
INIs
raltegravir dolutegravir elvitegravir
35
S/E of efavirenz
new onset psychiatric symps
36
S/E of tenofovir
GI upset
37
S/E of emtricitabine
rash and darkening of palms or soles
38
S/E of lamivudine
insomnia
39
S/E of rilpivirine
depression (more common if prev MH problems)
40
F/U for HIV patients
CD4 count and HIV Viral load every 3-6 months
41
Transmission of Hep A
faecal oral
42
What type of virus is Hep A
RNA virus
43
Hep A antibodies and what they mean
Anti HAV IgM - suggests recent infection - persists for 4-6m Anti HAV IgG - persists lifelong - confers protection
44
Most Hep A becomes chronic T or F
False Most cases self-resolve and don't require Rx
45
What type of virus is Hep B
DNA virus
46
Transmission of Hep B
vertical or by blood or blood products
47
Hepatitis B surface Antigen (HbsAg)
detected in acute or chronic infection
48
Hepatitis B core antibody (anti-HbC)
appears at the onset of symptoms persists for life indicates previous or ongoing infection
49
Hepatitis B e Antigen (HBeAg)
indicates replication and high levels of the virus
50
Hepatitis B e antibody (HBeAb or Anti-HBe)
Seroconversion and spontaneous clearance
51
Hepatitis B surface antibody (anti-HBs)
recovery and immunity successful vaccination
52
Most Hep B becomes chronic T or F
False Most acute cases self resolve and dont require treatment
53
When is treatment for Hep B indicated
Evidence of compensated liver disease AND raised ALT/fibrosis
54
Most Hep C becomes chronic T or F
True 80% develop chronic infection