adrenal

Question 1

Cushing syndrome results from effects of

Answer 1

supraphysiologic glucocorticoid concentrations

Question 2

Cushing syndrome results from effects of supraphysiologic glucocorticoid concentrations
originating from either

Answer 2

exogenous administration or endogenous overproduction
by the adrenal gland (adrenocorticotropic hormone [ACTH] dependent) or by
abnormal adrenocortical tissues (ACTH independent).

Question 3

ACTH-dependent Cushing syndrome (80% of all Cushing syndrome cases) is usually
caused by

Answer 3

overproduction of ACTH by the pituitary gland,

Question 4

overproduction of ACTH by the pituitary gland, causing

Answer 4

bilateral adrenal
hyperplasia