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Flashcards in Adrenergic Agonists Deck (12):
0

Adrenergic agonists

Produce their effects by activating adrenergic receptors; sympathomimetic
-Broad spectrum of application: congestive heart failure (CHF), asthma, preterm labor

1

Catecholamines

Cannot be used orally, brief duration of action, cannot cross the blood brain barrier

2

Noncatechlamines

Can be given orally, metabolized slowly by MAO/longer half life, more able to cross blood brain barrier

3

Albuterol

Beta2 receptors only

4

Isoproterenol

Beta1 and beta1 receptors

5

Epinephrine

Alpha1, alpha2, beta1, and beta2

6

Clinical applications of alpha1

Vasoconstriction, mydriasis

7

Drugs capable of activating alpha1 receptors

Epinephrine, norepinephrine, phenylephrine, dopamine

8

Therapeutic applications of alpha1 activation

Hemostasis, nasal decongestion, adjunct to local anethesia, elevation of blood pressure, mydriasis

9

Adverse effects of alpha1 activation

Hypertension, necrosis, bradycardia

10

Alpha2 activation

CNS: reduction of sympathetic outflow to heart and blood vessels; relief of severe pain

11

Beta1 activation therapeutic applications

Cardiac arrest, heart failure, shock, AV heart block