Adrenergic Blocking Antagonists T-2 Flashcards
Adrenergic blocking agents prevent?
norepinephrine from activating the receptor
Indications for alpha and beta adrenergic blocking agents:
essential HTN
Contraindications for alpha and beta adrenergic blocking agents:
- bradycardia or heart block
- shock or CHF
Caution for alpha and beta adrenergic blocking agents:
- bronchospasm
Drug to drug interactions for alpha and beta adrenergic blocking agents:
- enflurane, halothane or isoflurance anesthetics
- diabetic agents
- calcium channel blockers
Prototype for alpha and beta blocking agents:
Labetalol
Alpha adrenergic blocking agent actions:
blocks postsynaptic alpha 1 receptors, decreasing sympathetic tome in vasculature and causing vasodilation
Contraindications for alpha adrenergic blocking agents:
- allergy
- CAD or MI
Cautions for alpha adrenergic blocking agents:
- pregnancy or lactation
Adverse reactions for alpha adrenergic blocking agents:
- hypotension, orthostatic hypotension, angina, MI, CVA
- arrhythmia, weakness, and dizziness
Drug to drug interactions for alpha adrenergic blocking agents:
- ephedrine and epinephrine
- alcohol
Prototype for alpha adrenergic blocking agent:
Phentolamine
Alpha 1 selective blockers block the?
postsynaptic alpha 1 receptor site
Indications for alpha 1 selective blockers:
- BPH
- HTN
Contraindications for alpha 1 selective blockers:
- allergy
- lactation
Caution for alpha 1 selective blockers:
- CHF
- renal failure
Adverse effects for alpha 1 selective blockers:
- dizziness, weakness, fatigue
- N/V, abdominal pain, diarrhea
- arrhythmias, hypotension, edema, CHF, and angina
Drug to drug interactions for alpha 1 selective blockers:
- vasodilators and antihypertensive
Prototype for alpha 1 selective blockers:
Doxazosin
Indications for beta-blockers:
- treating cardiovascular problems: HTN, Angina, Mirgraine headaches
- preventing reinfarction after MI
Contraindications for beta blockers:
- allergy
- bradycardia, heart block, shock, CHF
- COPD, asthma
Caution for beta blockers:
- diabetes, hepatic dysfunction
Adverse reactions for beta blockers:
- fatigue, dizziness, depression, sleep disturbances
- bradycardia, heart block, hypotension
- bronchospasm
- N/V/D
- decrease libido
Drug to drug interactions for beta blockers:
- clondine
- NSAIDS
- insulin or anti-diabetic medications