Adrenergic Bronchodilators Flashcards
Name the 9 Adrenergic Bronchodilators
Generic Names (9)
- Albuterol
- Levalbuterol
- Salmetrol
- Formoterol
- Arformoterol
- Indacterol
- Olodaterol
- Vilanterol
- Recemic Epinephrine
Name the 9 Adrenergic Bronchodilators
Trade Names (9)
- Proventil, Ventolin
- Xopenex
- Serevent Diskus
- Performist
- Brovana
- Arcapta Neohaler
- Stiverdi Respimat
- Combo MED
- VapoNephrine, Micronefrin
Adrenergic Bronchodilators
What are the Receptors
SABA’s and LABA’s: Beta-1 and Beta -2
Racemic Epinephrine: Alpha and Beta 1 & 2 Receptors
Adrenergic Bronchodilators
What is the Mode of Action
Beta-1 Receptors: Increased heart rate and heart contractility.
Beta-2 Receptors: Relaxes bronchial smooth muscle and stimulates mucociliary activity.
Alpha, Beta -1, Beta-2: (Racemic Epinephrine) Beta’s same as above
Alpha: Increases blood pressure and vasoconstriction
Adrenergic Bronchodilators
What is the Duration for:
Short Acting (SABA)
Long Acting (LABA)
Ultra-Short Acting
SABA: 5-12 Hours. Albuterol and Levalbuterol
LABA: 12 Hours. Salmetrol, Formoterol, Arformoterol
LABA: 24 Hours. Indacaterol, Olodacterol, Vilanterol
Short-Acting: 0.5-2 Hours. Racemic Epinephrine
Adrenergic Bronchodilators
What are the Hazards (8) (7)
SABA’s & LABA’s
1. Tremors
2. Palpitations
3. Tachycardia
4. headache
5. Dizziness
6. Nausea
7. Decreased bronchodilator effect
8. Loss of bronchoprotection
Racemic Epinephrine
1-6 same as above +
7. Increase in blood pressure
Adrenergic Bronchodilators
Albuterol
Trade Names
Dosages
Trade Names:
Proventil
Ventolin
Dosages:
SVN: 0.5% Solution, 0.5 mL= (2.5 mg)
Adults: 2.5 mg/3 mL
Peds: 1.25 mg/3 mL
Neo: 0.63 mg/3 mL
Q4, QID, TID, BID
MDI: 90 mcg/puff
Adrenergic Bronchodilators
Levalbuterol
Trade Names
Dosages
Trade Names:
Xopenex
Dosages:
SVN: 0.31 mg/3 mL TID, 0.63 mg/3 mL TID, or 1.25 mg/3mL TID.
MDI: 45 mcg/puff, 2 puffs q4-6h
Adrenergic Bronchodilators
Salmetrol
Trade Names
Dosages
Trade Names:
Serevent Diskus
Dosages:
DPI: 50 mcg/blister BID
Adrenergic Bronchodilators
Formoterol
Trade Names
Dosages
Trade Names:
Performist
Dosages:
SVN: 20 mcg/2-mL unit dose, BID
Adrenergic Bronchodilators
Arformoterol
Trade Names
Dosages
Trade Names:
Brovana
Dosages:
SVN: 15 mcg/2-mL unit dose, BID
Adrenergic Bronchodilators
Indacaterol
Trade Names
Dosages
Trade Names:
Arcapta Neohaler
Dosages:
DPI: 75 mcg/inhalation, once daily
Adrenergic Bronchodilators
Olodaterol
Trade Names
Dosages
Trade Names:
Stiverdi Respimat
Dosages:
DPI: 2.5 mcg/acuation
Adrenergic Bronchodilators
Vilanterol (Has to be used in combo med)
Trade Names
Dosages
Trade Names:
Must be us in a Combo Med
Dosages:
IG: 25 mcg Qd with combo drug
Adrenergic Bronchodilators
Racemic Epinephrine
Trade Names
Dosages
Trade Names:
Vaponephrine, Micronefrin
Dosages:
SVN: 2.25% solution, 0.025-0.5mL QID
