Adrenoceptor Antagonists: Drug - Notes Flashcards Preview

D2: 609 Pharm and Pain Control > Adrenoceptor Antagonists: Drug - Notes > Flashcards

Flashcards in Adrenoceptor Antagonists: Drug - Notes Deck (13):
1

Phenoxybenzamine

a1
IRREVERSIBLE COVALENT BOND
SE: PHT, reflex increase in HR

2

Phentolamine

alpha antagonist
competitive
low use
SE: PHT reflex tachycardia

3

Prazosin

a1
competitive
NO reflex tachycardia
SE: 1st Pass Effect, PHT, Nausea, Drowsiness

4

Tamsulosin

a1
competitive
NO reflex tachycardia
SE: 1st Pass Effect, PHT, Nausea, Drowsiness

5

Propranolol

Non-selective BB
LA Action
no ISA
CI: HF, Asthma, Diabetes, Insomnia, Cardiac Depression, Raynaud

6

Pindolol

B antagonist
LA Action
no ISA
Angina commonly

7

Timolol

B antagonist
NO LA action
Glaucoma commonly

8

Metoprolol

b1 selective
LA action
NO ISA
SVT arrhythmia

9

Atenolol

b1
NO LA
No ISA
Low lipid solubility
CI: Preg

10

Nebivolol

b1 selective (less than 10 mg)
vasodilator
Nitrous Oxide
NO LA/ISA
Good Lipid Solubility

11

Esmolol

b1 selective
No LA/ISA
Very Short Acting (10 Mins)

12

Labetalol

B and A blocker
Some B agonist action
PHT

13

Carvedilol

B and A blocker
PHT
Commonly HF