ADRs Flashcards

1
Q

ABx to avoid in pregnancy

A

tetracyclines
aminoglycosides
sulphonamides and trimethoprim

quinolones: the BNF advises to avoid due to arthropathy in some animal studies

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2
Q

CVD drugs to avoid in pregnancy

A

ACE inhibitors
Angiotension II receptor antagonists
Statins
Warfarin

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3
Q

Diabetes drugs to avoid in pregnancy

A

sulfonylureas

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4
Q

Anti epileptics avoid in pregnany

A

sodium valp
Phenytoin
carbamazepine

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5
Q

Drugs that worsen psoriasis

A

BBlockers
lithium
antimalarials
NSAIDs
ACE inhibitors
infliximab

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6
Q

Contraindicated in HF

A

Verapamil
Pioglitazone
flecanide

NSAIDs/Glucocorticoids (use w caution as cause fluid retention)

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7
Q

Worsen seizure control

A

alcohol, cocaine, amphetamines
ciprofloxacin, levofloxacin
aminophylline, theophylline
bupropion
methylphenidate (used in ADHD)
mefenamic acid

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8
Q

Avoid in asthma

A

Bblockers
NSAIDs
Adenosine

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9
Q

Lithium SEs

mild toxicity

intermediate

Late

A

Tremor

lethargy

arythmias,seizures,coma,renal failure, diabetes inspidus

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10
Q

Fludrocortisone SEs

A

Hyptertension/soidum and water retention

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11
Q

Vancomycin
gentamicin
SEs

A

ototoxicity
nephtotoxicity

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12
Q

CCB SEs

A

hypotension, bradycardia, peripheral oedema, flushing

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13
Q

Metronidazole and disulfiram

A

sweating
flushing
N&V

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14
Q

MOA inhibitor SE

A

hypertensive crisis

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15
Q

do not prescribe ACEi w

A

NSAIDS

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16
Q

BBlockers contraindications

A

PVD
And asthma

17
Q

Ciclosporin ADRs

A

Nephrotoxic
HTN

18
Q

Bblockers SE

A

erectile dysfxn

19
Q

Tacrolimus w all heparins

A

increase k

20
Q

tramadol not with? why

A

SSRI
serotonin syndrome

21
Q

cyclizine SE

A

urinary retention/constipation
dry mouth

22
Q

fluoxetine SE

A

rash

23
Q

all heparins can cause

A

hyperkalaemia

24
Q

Aspirin SE

A

iron defiency anaemia

25
Q

Morphine ADRs

A

urinary retention
renal excreted so can accumulate in renal failure

26
Q

citalopram and dabigatran

A

precipitate bleed

27
Q

carbamazipine SE

A

hyponatraemia

28
Q

Omeprazole in increases risk of which infection

A

C.diff

29
Q

anticholinergic excess

A

‘mad, red, dry, blind’