Adult Urinary, Renal, Bladder disorder Flashcards
(78 cards)
List 4 urinary, renal, and bladder disorders in ADULTS?
- Polycystic Kidney Disease
- Kidney cancer
- Bladder cancer
- Bladder trauma
Disorder:
genetic disorder where multiple cysts form in the kidneys, leading to kidney enlargement and possible kidney failure.
Polycystic Kidney Disease (PKD)
Disorder:
Injury to the bladder from external forces
Bladder Trauma
There are 2 forms of Polycystic Kidney Disease (PKD)
- Childhood (Recessive) PKD
- Adult (Dominant) PKD (ADPKD):
PKD that is Inherited in a recessive manner.
(Recessive: inherrited from both parents)
Childhood (Recessive) PKD
PKD that is Inherited in a dominant manner.
(inherrited from one parent)
Adult (Dominant) Polycystic Kidney Disease (ADPKD)
S/S of PKD typically appear when cysts in the kidneys begin to ____.
enlarge.
PKD EARLY symptoms
List 8
- Nausea/vomiting
- Pruritus (itching)
- Fatigue
- Palpable bilateral enlarged kidneys (felt during a physical exam).
- Hematuria (blood in the urine) from cyst rupture.
- Urinary tract infections (UTI).
- Uremia (elevated UREA levels in urine, indicating kidney dysfunction).
- Hypertension: decreased kidney function
Q: What are some associated complications of Polycystic Kidney Disease (PKD)?
- Liver cysts – Cysts can develop in the liver, affecting its function.
- Heart valve abnormalities – PKD can cause issues with heart valves, such as mitral valve prolapse.
- Diverticulosis – The development of small pouches in the walls of the intestines, which can become inflamed or infected.
- Aneurysms – Weakening of the blood vessel walls, particularly in the brain, which can lead to an increased risk of rupture and hemorrhage.
5 PKD Diagnosis include:
- DNA Testing: genetic mutation
- Family History: important for dominant form
- Clinical Manifestations
- Ultrasound/CT scan
- IVP (Intravenous pyelogram)- detailed images of kidneys and urinary tract
Can patients with PKD progress to End Stage REnal Disease (ESRD)?
Yes!
About 50% of patients progress to ESRD by age 60.
What is the percent and age that patients with PKD progress to End stage Renal FAILURE
Renal disease and renal failure are diff- keep an eye!
70% by age 70
Is there a cure for PKD?
No. Treatment mainly focuses on managing symptoms and preventing complications
Collaborative Care for PKD
2 main ones
- Genetic Counseling: understand the risks of inheritance and potential implications for future generations
- Supportive Prevention/Treatment
Tx for ESRD and ESRF
List 3
- Nephrectomy (removal of kidneys) in some cases.
- Dialysis to filter waste and fluids from the body.
- Kidney Transplant as a potential long-term solution.
New Topic: Kidney Cancer
Most common type of malignant kidney tumor
adenocarcinoma
(Tubular epithelial cells of kidney)
Q: What are the early symptoms of kidney cancer?
No “specific” early symptoms
- Makes early detection challenging
Risk factors for kidney Cancer
- Smoking
- Family Hx
- Obesity
- HTN
- Exposure to asbestos, cadmium, gasoline
- Males > Females
Q: What are the classic manifestations of ADVANCED kidney cancer?
-
gross hematuria: Blood in the urine
-gross: visible to the eye - flank pain: Pain in the side or back- tumor pressing on surrounding tissues.
- palpable mass
Kidney cancer spreads beyond kidneys to nearby structures such as
- Renal Vein
- Vena Cava
- lungs
- liver
- long bones
DX studies for Kidney Cancer
- Intravenous Pyelogram (IVP) with Nephrotomography – Detects most kidney masses.
- Ultrasound – Helps differentiate between a tumor and a cyst.
- Angiography, percutaneous needle aspiration, CT scan, and MRI
- Cystoscopy with a renal biopsy
What labs are needed PRIOR to Intravenous Pyelogram (IVP)
Obtain baseline BUN/Creatinine
- due to contrast dye used
What should you monitor post dx studies
1 specific thing
Bleeding- procedures can cause bleeding.
What is a RADICAL NEPHRECTOMY surgery
- Entire kidney is removed.
- Removal of adrenal gland, surrounding fascia, part of ureter, & draining lymph nodes