Adverse Drug Reactions Flashcards

(79 cards)

1
Q

Which drug is known to cause acute intermittent porphyria?

A

Co-Trimoxazole

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2
Q

Which drug is known to cause agitation?

A

Cyclizine

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3
Q

Which three drugs are known to cause ankle oedema?

A

Angiotensin Receptor Blockers (ARBs)

Calcium Channel Blockers (CCBs)

Naproxen

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4
Q

Which two drugs are known to cause bradycardia?

A

Beta-Blockers

Digoxin

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5
Q

Which two drugs are known to cause circulatory collapse?

A

Isosorbide Mononitrate

Sildenafil

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6
Q

Which nine drugs are known to cause confusion?

A

Anticholinergic Drugs

Anticonvulsants

Antidepressants

Antipsychotics

Benzodiazepines (diazepam, temazepam, etc)

Corticosteroids

Metoclopramide

Opioids

Trazodone

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7
Q

Which two drug classes are known to cause constipation?

A

Antimuscarinics (tolteridone, etc)

Opioids

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8
Q

Which three drugs are known to cause candidiasis?

A

Amoxicillin

Clarithromycin

Corticosteroids

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9
Q

Which drug class is known to cause dehydration?

A

Diuretics

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10
Q

Which three drugs are known to cause diarrhoea?

A

Alendronic Acid

Magnesium Glycerophosphate

Proton Pump Inhibitors

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11
Q

Which drug is known to cause dry mouth?

A

Oxybutynin

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12
Q

Which two drug classes are known to cause dyspepsia?

A

Bisphosphonates - e.g. alendronic acid

Corticosteroids

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13
Q

Which seven drugs are known to worsen seizure control in epilepsy patients?

A

Ciprofloxacin

Levofloxacin

Aminophylline

Theophylline

Bupropion

Methyphenidate

Mefenemic Acid

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14
Q

Which drug class is known to cause erectile dysfunction?

A

Beta Blockers

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15
Q

Which drug is known to cause extra-pyramidal effects?

A

Metoclopramide

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16
Q

Which five drug classes are known to cause falls?

A

ACE Inhibitors

Antidepressants

Antimuscarnic Drugs - e.g. oxybutynin, etc

Benzodiazepines

Opioids

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17
Q

Which drug class is known to cause floppy iris syndrome?

A

Alpha Blockers - Tamsulosin

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18
Q

Which three drug classes are known to increase the risk of fractures?

A

Corticosteroids

GnRH Agonists

Proton Pump Inhibitors

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19
Q

Which three drugs are known to cause gastrointestinal bleeding?

A

Corticosteroids

NSAIDs

Bisphosphonates (alendrotnic acid, etc)

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20
Q

Which seven drugs are known to cause glucose intolerance?

A

Thiazide Diuretics

Corticosteroids

Antipsychotics

Tacrolimus

Ciclosporin

Interferon Alpha

Nicotinic Acid

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21
Q

Which drug class is known to cause a slight glucose intolerance, and should therefore be administered cautiously in diabetics?

A

Beta-Blockers

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22
Q

Which drug class is known to cause haematemesis?

A

NSAIDs

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23
Q

Which three drug classes are known to cause heartburn?

A

Antimuscarinic Drugs - e.g. tolterodine

Bisphosphonates - e.g. alendronic acid

Calcium Channel Blockers

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24
Q

Which drug is known to cause hearing difficulties?

A

Gentamicin

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25
Which five drugs are known to exacerbate heart failure?
Thiazolidinediones NSAIDs Corticosteroids Flecainide Verapamil
26
Which NSAID is an exception to the rule of heart failure exacerbation?
Low Dose Aspirin
27
Which drug is known to cause hepatic impairment?
Amiodarone
28
Which two drug classes are known to cause hyperglycaemia?
Corticosteroids Thiazide Diuretics
29
Which three drugs are known to cause hyperkalaemia?
ACE Inhibitors Aldosterone Inhibitors Ciclosporin
30
Which drug class is known to cause hypoglycaemic unawareness?
Beta-Blockers
31
Which two drugs are known to cause hypokalaemia?
Amiodarone Thiazide Diuretics
32
Which three drugs are known to cause hyponatraemia?
Bendroflumethiazide Citalopram Indapamide
33
Which eight drugs are known to cause a decrease in INR levels?
SCRAP GP Sulphonylureas Carbamazepine Rifampicin chronic Alcohol intake Phenytoin Griseofulvin Phenobarbitone
34
Which fourteen drugs are known to cause an increase in INR levels?
SICKFACES.COM Sodium Valproate Isoniazid Cimetidine Ketoconazole Fluconazole Acute Alcohol Intake/Allopuronol/Amiodarone Chloramphenicol Erythromycin Sulfonylureas Ciprofloxacin/Clarithromycin Omeprazole Metronidazole
35
Which drug is known to cause iron deficiency anaemia?
Aspirin
36
Which drug is known to cause jaundice?
Flucloxacillin
37
Which drug is known to cause lactic acidosis?
Metformin
38
Which drug is known to cause leucopenia?
Methotrexate
39
Which five drugs are known to cause medication overuse headaches?
Aspirin Codeine Ergotamine Paracetmaol Triptans
40
Which drug is known to cause myositis?
Diltiazem
41
Which four drugs are known to cause oculogyric crisis?
Haloperidol Metoclopramide Phenothiazines Risperidone
42
What are the three features of oculogyric crisis?
Agitation Restlessness Involuntary Upward Deviation of the Eyes
43
What is the first line management option of oculogyric crisis?
Procyclidine
44
What are the four drugs which cause pancreatitis?
Azathioprine Corticosteroids DDP-4 Inhibitors - 'gliptin' GLP-1 Agonists - 'tide'
45
Which drug class is known to exacerbate peripheral vascular disease - such as ischaemic leg ulcers?
Beta-Blockers
46
Which drug class is known to cause orthostatic hypotension?
Alpha Blockers - e.g. 'sin'
47
Which three drugs are known to cause polymorphic ventricular tachycardia - such as Torsades de Pointes?
Citalopram Fluconazole Ranolazine
48
Which seven drugs are known to exacerbate psoriasis?
NSAIDs ACE Inhibitors Beta-Blockers Lithium Chloroquine Hydroxychloroquine Infliximab
49
Which five drugs are known to cause pulmonary fibrosis?
Cytotoxic Agents Anti-Rheumatoid Drugs Dopamine Receptor Agonists Amiodarone Nitrofurantoin
50
Which drug is known to cause retinopathy?
Hydroxychloroquine
51
Which drug is known to cause sleep disturbances?
Mirtazapine
52
Which drug is likely to cause tendonitis?
Quinolone Antibiotics - 'floxacin'
53
Which four drugs are used to treat tuberculosis?
RIPE Rifampicin Isoniazid Pyrazinamide Ethambutol
54
What are the three side effects of rifampicin?
'R = Red Secretions' Flu-Like Symptoms Hepatitis Orange Secretions
55
What are the three side effects of isoniazid?
'I = I'm so numb' Peripheral Neuropathy Hepatitis Agranulocytosis
56
In order to prevent the side effect of peripheral neuropathy with isoniazid, which drug can be administered?
Pyridoxine (Vitamin B6)
57
What are the four side effects of pyrazinamide?
Hyperuricaemia (Gout) Arthralgia Myalgia Hepatitis
58
What is the side effect of ethambutol?
'E = Eye Issues' Optic Neuritis
59
Which two drug classes are likely to cause vomiting?
GLP-1 Analogues - 'tide' Macrolide Antibiotics - 'mycin'
60
Which nine drugs are known to cause urinary retention?
Alcohol Alpha-Adrenoreceptor Agonists Anticholinergics Antihistamines Benzodiazepines Calcium Channel Blockers NSAIDs Opioids Tricyclic Antidepressants
61
Which two drug classes commonly result in the adverse effect of hypoglycaemia?
Insulin Sulphonureas
62
Which five drug classes commonly result in the adverse effect of hyperglycaemia?
Antipsychotics Beta-Blockers Steroids Tacrolimus Thiazides
63
Which seven drug classes commonly result in the adverse effect of constipation?
Anticholinergics Antiemetics Antiepileptics Calcium Channel Blockers Diuretics Iron Opioids
64
Which six drug classes commonly result in the adverse effect of diarrhoea?
Antacids Antibiotics Colchicine Laxatives Metformin Protein Pump Inhibitors
65
Which two drug classes commonly result in the adverse effect of urinary retention?
Anticholinergics Opoids
66
Which four drug classes commonly result in the adverse effect of urinary incontinence?
Alpha-Blockers Anticholinesterase Inhibitors Clozapine Diuretics
67
Which three drug classes commonly result in the adverse effect of confusion?
Anticholinergics Opioids Sedatives
68
Which seven drug classes commonly result in the adverse effect of falls?
Antidepressant Antihypertensives Antiepileptics Antipsychotics Benzodiazepines Opioids Parkinson's Drugs
69
Which drug class commonly results in the adverse effect of gout?
Direutics
70
Which four drug classes commonly result in the adverse effect of osteoporosis?
Luteinising Hormone Releasing Hormone Agonists Proton Pump Inhibitors Steroids
71
Which four drug classes commonly result in the adverse effect of hypertension?
Mirabegron NSAIDs Oral Contraceptives Steroids
72
Which two drug classes commonly result in the adverse effect of hypercholesterolaemia?
Steroids Thiazides
73
Which four drug classes commonly result in the adverse effect of hypokalaemia?
Loop Diuretics Salbutamol Steroids Thiazides
74
Which six drug classes commonly result in the adverse effect of hyperkalaemia?
ACE Inhibitors Angiotensin Receptor Blockers (ARBs) Blood Transfusion Low Molecular Weight Heparin (LMWH) Potassium Sparing Diuretics Unfractioned Heparin
75
Which five drug classes commonly result in the adverse effect of hyponatraemia?
Carbamazepine Opioids Protein Pump Inhibitors (PPIs) Selective Serotonin Reuptake Inhibitors (SSRIs) Tricyclic Antidepressants (TCAs)
76
Which two drug classes commonly result in the adverse effect of hypernatraemia?
Demeclocycline Lithium
77
Which two drug classes commonly result in the adverse effect of hypotension?
Beta-Blockers Calcium Channel Blockers
78
Which two drug classes commonly result in the adverse effect of oral candidiasis?
Antibiotics Immunosuppressants Corticosteroids
79
Which drug class commonly results in the adverse effect of euglycemic diabetic ketoacidosis?
Sodium Glucose Co-Transporters (-glifozins)