Adverse drug reactions Flashcards

1
Q

Name 4 drugs (or classes) that may exacerbate HF symptoms

A
  • Verapamil
  • NSAIDs / glucocorticoids
  • Class I anti-arrhythmias (e.g. flecainide)
  • Thiazolidinediones
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2
Q

6 drugs that may worsen seizure control in epileptics

A
  • Alcohol, cocaine, amphetamines
  • Ciprofloxacin, levofloxacin
  • Aminophylline, theophylline
  • Bupropion
  • Methylphenidate
  • Mefenamic acid
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3
Q

Which drugs may exacerbate symptoms of asthma/COPD?

A
  • NSAIDs
  • Β-blockers
  • Adenosine (use verapamil instead)
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4
Q

Name 4 classes of antibiotics which should be avoided in pregnancy

A
  • Tetracyclines
  • Aminoglycosides
  • Sulphonamides and trimethoprim
  • Quinolones
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5
Q

Not including antibiotics, which drugs should be avoided in pregnancy?

A
  • Warfarin
  • ACE inhibitors, angiotensin II receptor antagonists
  • Statins
  • Sulfonylureas
  • Retinoids (including topical)
  • Cytotoxic agents
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6
Q

What drugs might exacerbate psoriasis?

A
  • Β-blockers
  • Lithium
  • Antimalarials (chloroquine and hydroxychloroquine)
  • NSAIDs
  • ACE-inhibitors
  • Infliximab
  • Withdrawal of systemic steroids
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7
Q

What are some adverse reactions of memantine?

A
  • Drowsiness
  • Constipation
  • Headache
  • Hypertension
  • Hallucinations
  • Balance problems
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