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Pharmacotherapeutics > Adverse Effect Of Medications > Flashcards

Adverse Effect Of Medications Flashcards

(60 cards)

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1
Q

Amino glycosides

A

Ototoxicity
Nephrotoxicity

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2
Q

Tetracyclines

A

Photosensitivity
Tooth discoloration
Esophageal irritation
Intracranial hypertension

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3
Q

Bisphosphonates

A

Eosophageal irritation
Hypophosphotemia
Osteonecrosis of the jaw
Atypical femoral fracture

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4
Q

Cyclophosphamide ifosfamide

A

Hemorrhagic cystitis

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5
Q

PDE5 inhibitors

A

Hypotension
Tachycardia
Nasal congestion
Headache
Dizziness

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6
Q

Statins

A

Rhabdomyolysis
Diabetes
Elevated liver enzymes

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7
Q

Lamotrigine

A

Skin rash

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8
Q

Isoniazid’s

A

Pyrodoxine deficiency
Peripheral neuropathy
Hepatotoxicity

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9
Q

Amiodarone

A

Pulmonary toxicity
Thyroid abnormalities
Blue-Gray skin discoloration
Phototoxicity
Corneal microdeposits

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10
Q

Vancomycin s/e

A

Ototoxicty
Hepatotoxicity
Red man’s syndrome
Nephrotoxicty
Blood disorder-thrombocytopenia

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11
Q

Quinine

A

QT prolongation
Deafness
Blindness
Conchonism

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12
Q

Flouroquinolones

A

Tendon rupture
QT prolongation
lowering seizure threshold

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13
Q

Corticosteroids

A

Osteoporosis
Steroid-induced diabetes
Mood/ behavioral
Hypertension, hypokalemia
Edema
Immunosuppression

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14
Q

Opiods

A

Constipation
Euphoria
Respiratory depression
Itch
Pupillary depression

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15
Q

Metformin

A

Weight loss
Lactic acidosis
Vitamin B12 deficiency
Gastrointestinal upset

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16
Q

Trimethoprim

A

Gastrointestinal upset
Hyperkalemia
Elevated creatinine levels
Megaloblastic anemia

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17
Q

Phenytoin

A

Gingival enlargement
Hirsutism
Osteomalacia
Skin coarsening / acne
Nystagmus / ataxia
Purple glove syndrome

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18
Q

ACE inhibitors

A

Persistent, dry cough
Hyperkalemia
Hypotension
Renal failure

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19
Q

Aspirin

A

Bleeding
Stomach ulcers
Reye syndrome (under 16s)
Tinnitus (high doses)

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20
Q

Iron supplements

A

Black stools

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21
Q

Bismuth subgallate

A

Black tongue, black stools

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22
Q

Amphotericin B

A

‘Shake and bake’ reaction
Hypokalemia
Myocarditis
Hepatotoxicity
Kidney damage

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23
Q

Lithium

A

Hypothyroidism
Diabetes type 2
Kidney damage
Weight gain
Myoclonus

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24
Q

Clofazimine

A

Hyperglycemia
Brown-pink skin discoloration
Skin dryness, rash

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25
Ethambutol
Red-green colourblindness Optic neuritis Hepatotoxicity Peripheral neuropathy Hyperuricemia
26
Clozapine
Agranulocytosis Myocarditis Hypersalivation CNS effects Urinary incontinence GI hypomotility Bone marrow suppression
27
SSRIs
Weight disturbance Gastrointestinal upset QT prolongation Hyponatremia Bone fractures Serotonin syndrome Lower seizure threshold
28
Antimuscarinics
Tachycardia Dry mouth Blurred vision Urinary retention Constipation Drowsiness
29
Beta-2 agonists
Tachycardia Palpitations Anxiety Tremors Muscle cramps Hypokalemia Sweating Insomnia Agitation
30
Typical antipsychotics
Extrapyramidal side effects QT prolongation Sexual dysfunction
31
Atypical antipsychotics
Weight gain Diabetes type 2 Lipid abnormalities Extrapyramidal effects
32
Benzodiazepines
Drowsiness, sedation Respiratory depression Amnesia Decreased concentration
33
NSAIDs
Gastrointestinal bleeding Renal impairment Fluid retention Photosensitivity
34
Beta blockers
Bronchospasm Vivid dreams / nightmares Cold extremities Hypoglycemia
35
Methimazole
Agranulocytosis
36
Calcium channel blockers
Constipation Gingival overgrowth Ankle swelling Flushing
37
Rifampin
Hepatotoxicity Red urine, sweat, tears
38
Methotrexate
Hepatotoxicity Ulcerative stomatitis Infections Pulmonary fibrosis
39
Irinotecan
Extreme diarrhea
40
Cisplatin
Hearing loss Kidney damage High risk of vomiting
41
Flucytosine
Bone marrow suppression Loss of appetite Psychosis Renal damage
42
Macrolides
QT prolongation GI effects Ototoxicity (high doses) Cholestatic jaundice
43
Heparin Warfarin Antiplatelets Anticoagulants
Bleeding Thrombocytopenia (heparin)
44
Levothyroxine
Weight loss Trouble sleeping Tachycardia Anxiety Difficulty tolerating heat Palpitations
45
Thalidomide
Phocomelia / limb deformities
46
Carmustine Busulfan
Pulmonary toxicity
47
Iron dextran
Severe anaphylaxis
48
Capecitabine
Hand-foot syndrome
49
Tamoxifen
Uterine cancer Pulmonary embolism Reduced cognition Irregular periods Hot flashes
50
Nitrates
Flushing Headache Light-headedness Hypotension
51
Nitrofurantoin
Gastrointestinal upset Pulmonary fibrosis Brown discolored urine Peripheral neuropathy Elevated liver enzymes Hemolyticanemia
52
Thiazolidinediones
Anemia Dizziness, headache Edema Bladder cancer Bone fractures Hepatotoxicity
53
Valproate
Gastrointestinal upset Tremor, ataxia, behavioral effects Increased liver enzymes Thrombocytopenia Hair loss Pancreatitis
54
Itraconazole
Vision disturbances Heart failure Skin rash Hepatotoxicity
55
Linezolid
Thrombocytopenia Peripheral neuropathy Serotonin syndrome
56
Metronidazole
Metallic-like taste Seizures Thrombophlebitis (IV use) Dark urine Peripheral / optic neuropathy Encephalopathy (high doses) Disulfiram-reaction (with alcohol)
57
Loop diuretics
Dehydration Hypotension Low electrolyte state Hearing loss / tinnitus (high doses) Kidney failure (w/ NSAID + ACE inhibitor) Hyperuricemia
58
Aldosterone antagonists
Gynecomastia Hyperkalemia
59
Allopurinol
Skin rash, sometimes SJS/TEN Hypersensitivity reaction Bone marrow suppression
60
Colchicine
Rhabdomyolysis Bone marrow suppression Gastrointestinal upset

Pharmacotherapeutics (13 decks)

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