Adverse Reactions & Side Effects Flashcards

(56 cards)

1
Q

acetaminophen

A

Integumentary: Itching, rash
Gastrointestinal: upper
abdominal pain, loss of
appetite
Other: Overdose may cause
hepatotoxicity

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2
Q

activated charcoal

A

Gastrointestinal:
Emesis, constipation, black stools, diarrhea, bowel obstruction

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3
Q

adenosine

A

Note: Because adenosine has an extremely short half-life, adverse reactions and side
effects are usually transient and of short duration.
–Cardiovascular: Dysrhythmias (including asystole), hypotension, chest pain, tachycardia
–Neurological: Feeling of impending doom, nervousness, dizziness, paresthesia Use with
caution in patients with hx of seizures.
–Integumentary: Flushing, sweating
–Respiratory: Severe bronchospasm in patients with hx of asthma and COPD - use with caution in these patients

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4
Q

albuterol

A

–Cardiovascular: Dysrhythmias, chest pain, palpitations
–Neurological: Tremors, headache, nervousness, dizziness

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5
Q

amiodorone

A

Cardiovascular: Hypotension, heart failure, worsening of dysrhythmias, prolonged QT
interval, bradycardia, AV block
Respiratory: Cough, progressive dyspnea
Neurological: Dizziness, fatigue
Other: Burning at IV site, Stevens-Johnson syndrome

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6
Q

aspirin

A

Respiratory: Bronchospasm/wheezing in allergic patients
Gastrointestinal: GI bleeding, epigastric distress, heartburn
Other: Anaphylaxis, Reye syndrome

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7
Q

atropine

A

Note: Expected effects of anticholinergics include pupillary dilation, dry
mouth/nose/skin, urinary retention, and constipation.
Cardiovascular: Palpitations, dysrhythmias
Neurological: drowsiness, confusion, headache, blurred vision

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8
Q

calcium chloride

A

Cardiovascular: bradycardia, asystole, hypotension, coronary artery spasm, syncope
Neurological: cerebral artery spasm
Other: metallic taste with rapid injection, tissue necrosis at injection site

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9
Q

calcium gluconate

A

Cardiovascular: bradycardia, asystole, hypotension, coronary artery spasm, syncope
Neurological: cerebral artery spasm
Other: metallic taste with rapid injection, tissue necrosis at injection site

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10
Q

dexamethasone

A

Note: all listed side effects are from cumulative doses or prolonged use.
Neurological: headache, restlessness, nervousness, increased appetite, insomnia
Other: retention of sodium and water

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11
Q

dextrose

A

Neurological: Cerebral hemorrhage, cerebral ischemia
Other: Warmth, pain, burning or phlebitis from IV infusion

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12
Q

diazepam

A

Cardiovascular: Hypotension, reflex tachycardia, thrombosis
Neurological: Dizziness, drowsiness, confusion, headache, ataxia, muscle weakness

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13
Q

diltiazem

A

Cardiovascular: Cardiac arrest, dysrhythmias, heart failure, hypotension, syncope, chest
pain, peripheral edema
Neurological: Dizziness, weakness, headache
Respiratory: dyspnea

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14
Q

diphenhydramine hydrochloride

A

Note: Hallucinations, confusion, and paradoxical CNS excitation can occur in children.
Cardiovascular: Dysrhythmias, palpitations, hypotension
Neurological: Seizures, dizziness, headache, blurred vision
Respiratory: wheezing, thickening of bronchial secretions

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15
Q

dopamine hydrochloride

A

Cardiovascular: Dysrhythmias, hypotension, hypertension, palpitations, chest pain
Respiratory: Dyspnea
Neurological: Headache, anxiety

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16
Q

epinephrine

A

Cardiovascular: dysrhythmias, chest pain, increased myocardial oxygen demand,
palpitations, hypertension
Neurological: Nervousness, restlessness, headache, tremor

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17
Q

etomidate

A

Cardiovascular: Dysrhythmias, hypotension, hypertension
Respiratory: Apnea of short duration, respiratory depression, hypoventilation,
hyperventilation
Neurological: Nystagmus, transient involuntary skeletal muscle movement

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18
Q

fentanyl citrate

A

Cardiovascular: Dysrhythmias, hypotension, syncope
Respiratory: Respiratory depression, chest wall rigidity
Neurological: Confusion, paradoxical excitation, delirium, drowsiness, fatigue
Other: abdominal pain, dehydration

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19
Q

flumazenil

A

Cardiovascular: dysrhythmias, chest pain, hypertension
Neurological: seizures, dizziness, agitation, confusion, headache, visual disturbances,
uncontrollable shivering, rigors
Other: hiccups, pain at the injection site

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20
Q

furosemide

A

Cardiovascular: Dysrhythmias, orthostatic hypotension, hypotension
Neurological: weakness, headache, dizziness
Other: Hyperglycemia, hypokalemia, dry mouth, diarrhea

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21
Q

glucagon

A

Cardiovascular: Hypotension, tachycardia
Neurological: Dizziness, headache
Other: Rebound hyperglycemia

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22
Q

glucose, oral

A

None

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23
Q

haloperidol

A

Cardiovascular: Hypotension, orthostatic hypotension, tachycardia. Excessive dosing and
off-label use may result in Torsades, QT prolongation and sudden death
Neurological: Seizures, confusion, restlessness, extrapyramidal/dystonic reactions,
blurred vision
Gastrointestinal: constipation, dry mouth, drooling

24
Q

hydromorphone

A

Cardiovascular: Hypotension, syncope
Respiratory: Apnea
Neurological: Dizziness, headache, drowsiness, weakness

25
hydroxycobalamin
Cardiovascular: Hypertension, GI bleed Respiratory: dyspnea Neurological: dizziness, headache
26
ibuprofen
Neurologic: headache, dizziness, drowsiness, fatigue, restless sleep, thirst, sweating, paresthesia, tinnitus, blurred vision, eye irritation Renal: Fluid retention, frequent urination
27
ipratropium bromide
Cardiovascular: Hypertension, tachycardia, palpitations, myocardial infarction Respiratory: Dyspnea, worsening COPD symptoms Neurological: headache, dizziness, nervousness, tremors Gastrointestinal: dry mouth, GI distress
28
ketamine
Cardiovascular: Hypertension, tachycardia Respiratory: respiratory depression, increased secretions, hypersalivation, laryngospasm Neurological: Hallucinations, nystagmus
29
ketorolac tromethamine
Cardiovascular: Vasodilation, hypotension, hypertension, GI bleeding, edema Respiratory: bronchospasm, dyspnea Neurological: Drowsiness, dizziness, headache, sedation
30
labetolol
Cardiovascular: bradycardia, heart failure, pulmonary edema, orthostatic hypotension, hypotension, ventricular dysrhythmias Neurological: Fatigue, weakness, depression, headache, dizziness Respiratory: Bronchospasm, dyspnea
31
lidocaine hydrochloride
Cardiovascular: Hypotension, dysrhythmias, cardiac arrest Neurological: Drowsiness, confusion, seizures, slurred speech
32
lorazepam
Cardiovascular: Hypotension, bradycardia Neurological: Drowsiness, dizziness Respiratory: Apnea
33
magnesium sulfate
Cardiovascular: Hypotension and bradycardia with rapid administration, vasodilation Respiratory: Respiratory depression, respiratory paralysis Neurological: Drowsiness, CNS depression, decreased deep tendon reflexes
34
mannitol
Cardiovascular: Tachycardia, chest pain, hypotension, hypertension, heart failure Neurological: Headache, confusion, blurred vision, rebound increase in ICP Metabolic: hypo/hyperkalemia, hypo/hypernatremia, dehydration
35
methylprednisolone sodium succinate
Cardiovascular: Heart failure, hypertension Neurological: depression, euphoria, headache, restlessness, seizure, increased ICP Other: fluid retention, peptic ulcer, hypernatremia, hyperkalemia, tuberculosis
36
midazolam hydrochloride
None
37
morphine sulfate
Cardiovascular: Hypotension, orthostatic hypotension, syncope, bradycardia, tachycardia Neurological: Confusion, headache Respiratory: Respiratory depression, apnea, dyspnea, bronchospasm
38
naloxone hydrochloride
Cardiovascular: Hypertension/hypotension with rapid administration, dysrhythmias Neurological: Restlessness, seizures, withdrawal symptoms in opioid-dependent patients Respiratory: dyspnea, pulmonary edema Other: Diaphoresis
39
nitroglycerin
Cardiovascular: Reflex tachycardia, syncope, hypotension Neurological: Headache, dizziness, weakness, muscle twitching Other: Diaphoresis, dry mouth
40
norepinephrine bitartrate
Cardiovascular: hypertension, dysrhythmias, chest pain, peripheral cyanosis, cardiac arrest, decreased blood flow to GI tract/kidneys/skin/skeletal muscles Neurological: Headache, anxiety, dizziness, restlessness Respiratory: Dyspnea Renal: Urinary retention, renal failure
41
ondansetron hydrochloride
Cardiovascular: Syncope, palpitations, dysrhythmias Neurological: Headache, serotonin syndrome Respiratory: Wheezing/bronchospasm Gastrointestinal/other: Malaise, constipation, diarrhea, hives, rash
42
oxygen
None
43
oxytocin
Cardiovascular:Hypotension, dysrhythmias Neurological: Coma, seizures, anxiety, maternal intracranial hemorrhage Other: Anaphylaxis, painful uterine contractions, electrolyte disturbances
44
phenylephrine
Cardiovascular: palpitations, hypertension Neurological: Tremors
45
pralidoxime
Cardiovascular: tachycardia, cardiac arrest Respiratory: Laryngospasm, apnea, hyperventilation Neurological: Dizziness, drowsiness, headache, seizures, neuromuscular blockade, muscle rigidity, muscle weakness
46
procainamide hydrochloride
Cardiovascular: dysrhythmias, severe hypotension, widening of QRS complex, PRI and QT intervals Neurological: Confusion, seizures
47
promethazine hydrochloride
Cardiovascular: Chest tightness, palpitations, bradycardia, reflex tachycardia, QT prolongation, orthostatic hypotension Neurological: Headache, dizziness, drowsiness, confusion, restlessness Respiratory: wheezing, thickening of bronchial secretions
48
rocuronium bromide
Cardiovascular: transient hypo/hypertension, dose-related tachycardia Respiratory: hiccups, wheezing Other: Injection site edema, itching, residual muscle weakness
49
sodium bicarbonate
Cardiovascular: Heart failure Respiratory: Pulmonary edema Neurological: Tremors, twitching, seizures Other: electrolyte imbalances VI. Dosage Adult: 1 mEq/kg slow IV/IO push Pediatric: 1mEq/kg slow IV/IO push. VII. Special Considerations ● Extravasation may cause tissue sloughing, cellulitis and necrosis. ● 4.2% concentration recommended for infants younger than 1 month. VIII. Drug Interactions ● Will precipitate with amiodarone. Use a different IV if possible. ● Likelihood of precipitating with other medications is high - flush IV very well. ● Decreases the effects of benzodiazepines and TCAs.
50
succinylcholine chloride
Cardiovascular: cardiac arrest, dysrhythmias Respiratory: increased salivation Metabolic/Other: Prolonged muscle rigidity, rhabdomyolysis, malignant hyperthermia, hyperkalemia, increased intracranial/intraocular/intragastric pressure
51
terbutaline sulfate
Cardiovascular: dysrhythmias, chest pain Neurological: CNS stimulation, headache, seizures, restlessness Respiratory: bronchospasm/wheezing, coughing
52
thiamine hydrochloride
Cardiovascular: Vasodilation, hypotension Neurological: weakness Integumentary: Sweating, itching, hives
53
tranexemic acid
Cardiovascular: rapid infusion may cause hypotension, may increase risk of thromboembolic disorders, anemia Neurological: Fatigue, headache, dizziness Other: Abdominal pain, back pain, joint pain, musculoskeletal pain
54
vecuronium bromide
Respiratory: excessive salivation Neurological: prolonged neuromuscular blockade Other: Itching, hypersensitivity reactions associated with histamine release
55
verapamil hydrochloride
Cardiovascular: dysrhythmias (including AV blocks and asystole), decreased myocardial contractility, vasodilation Neurological: Dizziness, headache
56