Aetiology of Amblyopia Flashcards

(32 cards)

1
Q

what is the critical period for visual development

A

7-8 yrs

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2
Q

what is the sensitive period

A

time of deprivation to teen age years

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3
Q

why is the brain vulnerable

A

neural plasticity

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4
Q

when is amblyopia thought to start

A

when baby is binocular (2-4 months)

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5
Q

does the age of the px affect the response to treatment

A

yes - the younger the px the more rapid the improvement

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6
Q

why does the age matter in relation to response of treatment

A

due to the neural plasticity

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7
Q

what is the exception of treatment beyond age 8

A

anisometropic amblyopia or those with no previous treatment

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8
Q

what else can amblyopia affect

A
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9
Q

What are the two mechanisms for amblyopia

A

deprivation of form vision - passive element and abnormal binocular interaction or competition - active/dynamic element

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10
Q

what did Hubel and Wiesel (1965) do to test effects of strabismus

A

on cats - surgically induced or lid suturing to prevent BSV - have an abnormally high proportion of monocular cells at the visual cortex where there should be binocular cells

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11
Q

when are children most sensitive to amblyopia

A

0-3 yrs old

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12
Q

when does the sensitivity to amblyopia decrease

A

until 7yrs old

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13
Q

what do the X and Y cells do

A

send responses to the brain

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14
Q

where is our best vision in the eye

A

fovea

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15
Q

what do X cells do

A

respond to sustained stimulation (stable images, well focused images)

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16
Q

where are X cells most dense

17
Q

what are X cells poor at

A

spatial resolution and detecting contrast

18
Q

How many layers in the LGB

19
Q

does deficit in the LGN have an effect on amblyopia

A

yes makes it more dense

20
Q

what are ocular dominance columms

A

columnar arrangement of the cells in the striate cortex

21
Q

how much does 1D affect the response in cells

A

reduced affect in one cell

22
Q

how many D is a risk factor for child aged 1

A

3D - would mean they are likely to have this for the rest of their life.

23
Q

is amblyopia a genetic condition?

A

No but the amblyogenic factors are genetic

24
Q

what is the definition of amblyopia

A

a reduction in visual acuity secondary to neurological deficits in visual output but abnormal brain stimulation during critical periods of visual development.

25
what is the prevalence of amblyopia
1-5%
26
what is the most common cause of vision loss in infants and young children
amblyopia
27
true of false the prevalence of amblyopia is higher in lower socioeconomic classes
true
28
what are the 7 functional types of amblyopia
stimulus deprivation, strabismic, anisometropic, ametropic, meridional, idiopathic, hysterical/psychogenic
29
what is the type of organic amblyopia
toxic
30
can improvement be expected from functional amblyopia treatment
yes
31
what is organic (toxic) amblyopia
no lesion detectable, can be reversible or irreversible, consider if no response to treatment.
32