Ageing Flashcards

(38 cards)

1
Q

Causes of acute functional decline

A

About 4ish should be enough

  • Worsening of known medical conditions
    - New medical conditions e.g. stroke, infections, falls, delirium
    - Initiation of new medications
    - Electrolyte disturbances
    - Acute kidney injury / dehydration
    - Hypoglycaemia from glipizide with worsening renal function / poor oral intake
    - Poor medication compliance
    - Underlying dementia, frailty, caregiver / support issues
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2
Q

Strategies to prevent functional decline

A

Know all

- Being mindful of its likelihood
- Identifying and comprehensively assessing both general and body system specific high risk indicators
- Implementing preventive management strategies targeting ≥1 relevant domains, especially 
    - Cognition
    - Emotional health
    - Mobility
    - Self-care
    - Continence
    - Nutrition
    - Skin integrity
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3
Q

Determinants of Active Ageing

A

Know ALL

  • Social
    • Economic
    • Health and Social services
    • Behavioural
    • Personal
    • Physical
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4
Q

Determinants of Active Ageing

A

Know ALL

  • Social
    • Economic
    • Health and Social services
    • Behavioural
    • Personal
    • Physical
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5
Q

Health strategies in the management of function in the elderly

A

Know ALL

  • Preventive - prevent health condition, reduce incidence
  • Curative - cure, control disease and consequences
  • Rehabilitative - restore full, or optimise function
  • Supportive - preserve independence and autonomy, optimise QoL
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6
Q

Components of Rehabilitation Goal Setting

A

Memorise a few

  • Ascertain what is important to the patient and family
  • Explain likely degree of restoration of activity (acknowledge uncertainty)
  • Explain what is required from the patient
  • Discharge planning starts early
  • Review goals as patient progresses
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7
Q

Factors predisposing to ADRs

A

Know a few

  • Polypharmacy - more health conditions so more meds, DDIs
  • Decline in renal and liver function - reduced clearance and excretion of drugs
  • Cognitive impairment - under consume, over consume drugs
  • Poor eyesight - under consume, over consume drugs
  • Physical limitations - May not pack pills properly, break pills in half etc.
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8
Q

Complications of immobility

A

Know a few, at least 6

  • Complications
    • Muscles: decreased muscle strength, contractures (weakness)
    • Skin: pressure ulcers
    • Deconditioning
    • Cardiovascular: decreased work capacity, DVT, postural hypotension
    • Respiratory: decreased ventilation, V/Q mismatch, hypostasis pneumonia
    • Joint: loss of full range of motion
    • CNS: deterioration in balance and coordination
    • Genitourinary: incomplete bladder emptying, incontinence
    • GI: decreased appetite, constipation, GER & aspiration
    • Metabolic: insulin Resistance, hypercalcemia
    • Bone: bone loss, increased fracture risk
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9
Q

Predisposing factors for fall

A
  • Neuromuscular change - e.g. old stroke, age
  • Multiple comorbidities - polypharmacy, diabetes
  • Age - increased sway, slower righting reflex
  • Poor vision - age, DM
  • Knee osteoarthritis
  • Inactivity
  • All lead to impaired strength and balance
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10
Q

Precipitating factors for fall

A
  • Poor lighting
  • Home hazard
  • Medications
  • Increased fall risk
  • Intercurrent illness
    • Hypotensive
    • Tired / distracted
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11
Q

Broad reasons why elderly are prone to falls

A

Physiological changes with ageing
Pathological changes with ageing
Medications
Environment

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12
Q

Physiological changes with ageing

A

Know a few
- Loss of accommodation
- Loss of contrast acuity
- Increased postural sway
- Decreased proprioception
- Decreased muscle tone
- Slower righting reflex
- Slower reaction time
- (Reduced pulmonary vital capacity, GFR)
- Increased risk of postural hypotension
- Blunted baroreceptor response
- Decreased cardiac response to sympathetic stimulation
- Diuretic use and age-related changes to renal function
- Nocturia from decreased nocturnal ADH

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13
Q

Factors to consider when prescribing in elderly

A

Patient factors
- Physiological function
- Underlying illness
- Accurate clinical diagnosis

Drug factors
- Pharmacology
- MoA, Efficacy
- Safety - ADR, DDIs
- Suitability

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14
Q

Dealing with communication issues

A
  • Hearing
    • Face patient in bright room
    • Lower tone, DO NOT SHOUT
    • Eliminate noise
    • Amplification device
    • Dementia / confused, use simple commands
  • Come up with more, generally should be intuitive - use visual aids, write down, shorter sentences etc.
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15
Q

Comprehensive Geriatric Assessment components

A
  • Multidimensional
  • Determine medical, functional, psychological capabilities
  • To develop coordinated, integrated plan for treatment and long-term follow up
  • Components
    • Medical Assessment
      • Problem list
      • Comorbidities, disease severity
      • Medications
      • Nutritional status
    • Function Assessment
      • ADLs, IADLs
      • Activity and exercise
      • Gait and balance
    • Psychological Assessment
      • Mental status (cognitive) testing
      • Mood/depression testing
    • Social Assessment
      • Informed support needs and assets
      • Eligibility / financial assessment
    • Environment Assessment
      • Home safety
      • Transportation
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16
Q

ADLs and IADLs

A
  • ADLs
    • Dressing
    • Eating
    • Ambulating
    • Toileting
    • Hygiene
    • Swallowing
  • IADLs
    • Shopping
    • Housekeeping
    • Accounting
    • Food prep
    • Take meds
    • Transport
    • Telephone
17
Q

Physiological vs Pathological Ageing

A

Physiological - normal physiological processes that occur with ageing; typically begins in the third decade and is progressive (e.g. age related GFR and Vital Capacity declines)

Pathological - cumulative effects of age-associated diseases over time (e.g. BPH, cataracts)

18
Q

Demography vs Epidemiology

A

Demography - The statistical study of populations

Epidemiology - Factors affecting the patterns of health and illness of populations

19
Q

Life Course Approach to maintaining functional capacity

A

Early life - growth and development

Adult life - maintaining highest possible level of function

Older age - maintaining independence and preventing disability

(i.e. postpone chronic diseases and disability as much as possible by increasing and maintaining physiological reserves, above the disability threshold)

20
Q

What is frailty

A

A complex, multidimensional and cyclical state of diminished physiological reserve

Increase vulnerability to adverse clinical outcomes such as disability, delirium, falls, and death

Increased vulnerability to stressors

Is a dynamic process and may be reversible

21
Q

Age-related cognitive changes

A

Non-uniform (Affects some domains more than others)

Slowed speed of processing (“bottleneck”; decreased ability to reason well and quickly in novel situations)

Compensated for by gains in experiential-based (crystalline) intelligence

Large individual differences in cognitive function

Forgetfulness is inconsistent and non-progressive

Absence of significant effects on one’s accustomed community, home and self care functioning

22
Q

Dementia risk factors

A

Non-modifiable
- Age
- Female gender
- Genetic factors
- Down’s syndrome
- Family history

Modifiable
- Hearing loss
- Traumatic brain injury
- Hypertension
- A lot of alcohol
- Obesity
- Smoking
- Depression
- Social isolation
- Physical inactivity
- Air pollution
- Diabetes

23
Q

What is dementia

A

An ACQUIRED syndrome of decline in memory and other cognitive domains SUFFICIENT TO AFFECT DAILY FUNCTIONING

Progressive and disabling

Not an inherent aspect of aging

Different from normal cognitive lapses

A clinical diagnosis

24
Q

Alzheimer’s Disease diagnosis

A

Amnesia + at least one of Apraxia, Aphasia, Agnosia or Executive dysfunction

Decline from baseline, impact on occupational and/or social functioning

(May see medial temporal lobe atrophy and small hippocampal volumes, and neurofibrillary tangles and amyloid plaques)

25
Dementia clinical features
Activities of daily living - Loss of independence in accustomed ADLs Behaviour Cognitive - Memory deficit (recent > remote) - Other domains (disorientation, impaired judgement and problem solving, language, praxis, visuospatial)
26
Dementia impact
Caregiver burden, caregiver burnout and institutionalisation as needs outweigh resources Role strain (demands of care, social impact and control over the situation) Personal strain (psychological impact) Chinese ethnicity - filial piety and obligation to care leads to greater worry about performance and caregiver stress
27
Depression
Mental disorder characterised by low mood and loss of interest and can present with affective, physical and cognitive symptoms - can become chronic or recurrent, and lead to substantial impairments in an individual's ability to take care of one's everyday responsibilities
28
Depression mechanisms
Monoamine hypothesis - decreased neurotransmitter concentrations Cytokines Neuropeptides
29
Risk factors for depression in older persons
Chronic pain Impairment in physical function Drugs (e.g. B-blockers) Sensory deprivation (hearing, vision) Dementia
30
Clinical features of depression
Affective (Mood) - low mood, sadness; loss of interest of pleasure in usual activities; guilt; worthlessness; suicidal ideas Behavioural - psychomotor slowing or agitation; fatigue or loss of energy; poor sleep; altered appetite Cognitive - poor memory, concentration or decision-making
31
Late-onset depression
First depression after age 65 - Higher risk of dementia, less likely to have family history - Greater association with co-morbid conditions ("vascular depression" in hypertension, IHD, stroke) - More emphasis on physical and cognitive symptoms, fewer mood symptoms
32
Why is late-onset depression under-diagnosed
- Mistaken for normal ageing - Symptoms attributed to medical illness - Reluctance to stigmatise patient with psychiatric diagnosis - Non-specific, atypical presentation - Overlapping symptoms with other conditions
33
Why treat depression
- Over-investigation of somatic symptoms - Increased physician visits and hospitalisations - Decreased QoL - Can aggravate certain medical conditions (e.g. IHD) - Increased caregiver stress - Increased nursing home placement - Risk of suicide
34
Delirium
Non-specific neuropsychiatric manifestation of a generalised disorder of cerebral metabolism and neurotransmission High predisposing factors (e.g. Dementia, functional impairment) can result in less noxious precipitating factors (urinary retention, sleep deprivation) presenting as delirium
35
Common causes of delirium
Drugs and Infection Also consider severe stuff like AMI, GI bleed etc. D: Drugs E: Eyes, ears L: Low O2 states (AMI, GI bleed) I: Infection R: Retention (Urine or Faeces) I: Ictal U: Undernutrition, underhydration M: Metabolic S: Subdural
36
Confusion Assessment Method CAM
Acute change in mental status AND Fluctuating course AND Inattention AND Either Disorganised thinking or Altered Level of Consciousness (Alert is normal, vigilant, lethargic, stupor, coma are abnormal)
37
Differentiate the 3Ds
Delirium vs Dementia vs Depression Onset: Acute vs Insidious vs Variable Course: Fluctuating vs Steadily Progressive vs Diurnal Variation Consciousness and Orientation: Clouded/Disoriented vs Clear until late stages vs Generally unimpaired Attention and Memory: Poor STM, inattention vs Poor STM without marked inattention vs Poor attention with relatively intact memory Psychosis: Common vs loss common vs small subset
38
Factora affecting successful rehabilitation
- Assessment: medical, physical, psychological, social domains - Suitability: Adequate baseline physical and psychological functioning - Type and Place: Acute hospital, rehab hospital, nursing home, day rehab center, at home