ageing Flashcards

(37 cards)

1
Q

State the main components that comprise the CGA?

A

Medical (Problem list, co-morbidities, medication review, nutritional status)
Functioning (Basic and extended ADLs, activity status, gait and balance)
Psychological (mental status, mood testing)
Social/ environment (Informal needs, social circle, care eligibility, safety)

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2
Q

State what delirium encompasses (AAID)

A

altered level of consciousness
Acute and fluctuating
inattention
disorganised thinking

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3
Q

What are the two broad categories of delirium?

A

Hypoactive (drowsy, reduced consciousness, withdrawn, apathetic, sleepy, coma increased risk of pressure sores) 2x mortality

Hyperactive (agitated, aggressive, wandering  increased falls risk)

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4
Q

Suggest two tools that can be used to assess the risk of the patient having delirium

A

4AT + CAM

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5
Q

componenets of 4AT

A
  • alertness
  • AMT4 (age, DOB, place, current year)
  • attention (months backward)
  • acute of fluctuating course
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6
Q

What dual medication therapy commonly used in UTIs should be avoided in a possible delirium

A

Trimethoprim and haloperidol

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7
Q

Why might you want to stop co-codamol in a patient with possible delirium and pain that isn’t too severe?

A

It can precipitate her delirium and codeine can be constipating

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8
Q

Why might you want to stop Bendroflumethiazide?

A

low Bp and cause falls

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9
Q

Scoring system for determining if there has been a stroke

A

ROSIER score

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10
Q

3 subcategories of stroke

A

Haemorrhage, Infarct, SAH

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11
Q

stroke symptoms Less than 24 hours =

A

TIA

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12
Q

Medications used in secondary prevention of stroke

A
Anticoagulants if cardioembolic/ AF 
Antiplatelets if not cardioembolic (first line Clopidogrel)
Stop smoking
Statins
Manage blood pressure
Diet and lifestyle advice
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13
Q

CHADSVASC score

A
Congestive HF
Hypertension
Age >75 - 2
Diabetes
Stroke/TIA/thromboembolism - 2
Vascular disease
Age 65-74
Sex Category - Female
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14
Q

If CHADSVASC greater than 1 then recommend

A

Warfarin/NOAC

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15
Q

What scoring system is used to weigh up the risk of bleeding on anticoagulants?

A

HASBLED - It assesses 1-year risk of majorbleedingin patients taking anticoagulants with atrial fibrillation

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16
Q

Which type of ischaemic stroke should not be treated with aspirin?

A

Cardioembolic (fibrin rich > anticoagulant required)

17
Q

worse prognosis stroke =

18
Q

how are telomeres the biological marker of ageing?

A

They progressively shorten with each cell replication, and eventually become too short to sustain cell replications (then leading to cell senescence)  shorter telomeres = shorter life expectancy

19
Q

What is meant by ‘frailty’?

A

Loss of homeostasis and resilience

Increased vulnerability to decompensation after a stressor event

Increased risk of falls, delirium, disability, death

20
Q

What physiological factors increase risk of falls in elderly?

A
  • vision: smaller pupils, lens thickening = ↓light
  • central processing and cognition = ↓reaction time
  • ↓cardiorespiratory fitness
  • sarcopenia (loss of muscle mass and function)
  • ↓peripheral sensation and proprioception, ↑postural sway
21
Q

causes of falls and syncope in elderly

A
Arrythmias
Orthostatic hypotension
Neurogenic (vasovagal)
Carotid sinus hypersensitivity
Valvular heart disease (Aortic stenosis)
22
Q

orthostatic hypotension is defined as

A

a fall in SBP >20mmHg or a fall in DBP >10mmHg after 3 minutes of standing

23
Q

how does cervical myelopathy present?

A

High stepping gait

+ve romberg test

24
Q

how does peripheral neuropathy present?

A

altered sensation

wide-based gait

25
there is strongest evidence for what intervention following a fall?
Strength and balance training
26
What should be stopped and started in med review following falls?
STOP >4 meds (independent risk factor for falls) psychoactive medication priority START Calcium/ vitamin D (best evidence in longerm care setting/ proven vit D deficiency) Fracture risk assessment/ osteoporosis treatment
27
Acidic drugs require an ______ environment for absorption
Acidic e.g. phenytoin, aspirin, penicillin Basic drugs require a basic environment for absorption (pH > 7.35) e.g. diazepam, morphine
28
Two main proteins for absorption in older people?
Albumin - acidic drugs | Alpha-1-Glycoprotein - basic drugs (more of this in elderly)
29
old people absorb basic drugs better due to
decreased gastric secretions | Higher levels of Alpha-1-Glycoprotein
30
What implication does decreased body water in old people have on the distribution of hydrophilic drugs? (e.g. Lithium, digoxin)
Lower Vd
31
side effects of opioids, steroids + levothyroxine in elderly?
Opioids – constipation (begin lactulose or senna prophylactically) impaired psychomotor, falls and confusion Steroids – osteoporosis prevention if long term. Steroid induced diabetes Levothyroxine – calcium interferes with absorption
32
Side effects of NSAIDS + Antibitoics
NSAIDS - GI haemorrage, decline in GFR, decreased diuretic effectiveness Antibiotics - resistance and CDiff
33
START drug rules
Antihypertensive: treat where systolic BP consistently > 160 ACEI: with chronic heart failure or post MI PPI: with aspirin and warfarin in combination Warfarin/ DOACs: chronic atrial fibrillation, following diagnosis of DVT or PE
34
how much morphine given for breakthrough pain?
1/6 of total background dose
35
What is sarcopenia?
Definition requires at least 1 + either 2 or 3 1) low muscle mass 2) low muscle strength 3) low physical performance muscle mass starts to decrease @ 30 then accelerates at 60
36
what drugs should be stopped in the following: Bleeding ulcer Kidney failure Hyponatraemia
- stop NSAID - stop ACEi - stop antidepressant
37
Meds given at end of life
Morphine injection 2mg subcutaneously hourly as required, midazolam injection 2mg hourly subcutaneously as required, hyoscine butylbromide (buscopan) injection 20mg hourly as required, [anti-muscarinic used for drying up resp secretions.] levomepromazine 2.5 mg injection 8 hourly subcutaneously as required. [broad spectrum anti-emetic].