Aging

Question 1

Aging, a process vs. life span from birth to death

Answer 1

maximal life span

life expectancy varies by

Question 2

intracellular changes

Answer 2

progressive shortening of telomeres in continuously-dividing cells
-accumulation of cellular mutations

Question 3

degenerative extracellular changes- 2 points

Answer 3

advanced glycation end-products induce cross-linking of proteins in collagen

cumulative cellular damge from effects of free radical that accumulate due to oxidative stress (malignant changes

Question 4

wear and tear theory

Answer 4

Wear and tear theories of biological aging propose that aging in humans and other animals is simply the result of universal deteriorative processes that operate in any organized system.

Question 5

cellular aging USE IT OR LOSE IT

Answer 5

atrophy, decreased function, and loss of cells

-cumulative damage to mtDNA (mitochondrial DNA)

Question 6

tissue and systemic aging

Answer 6

progressive stiffness and rigidity-blood vessels, ligaments, tendons

-sarcopenia-decreased muscle mass and strength

Question 7

frailty syndrome

Answer 7

mobility, balance, muscle strength, motor activity, cognition, nutrition, endurance, falls, fractures, and bone density