Albuterol (Proventil, Ventolin, Proair, Accuneb)

Question 1

Drug Class

Answer 1

Sympathomimetic, short-acting beta-2 adrenergic agonist

Question 2

Mechanism of Action

Answer 2

Selective beta-2 adrenergic agonist causes bronchial smooth muscle relaxation and inhibits mediator release from mast cells

Question 3

Indications and Contraindications

Answer 3

Indications: Treatment/prevention of bronchospasm in patients with reversible obstructive airway disease, hyperkalemia treatment

Contraindication: Dysrhythmias, especially those by digitalis. Synergistic with other sympathomimetics

Question 4

Side Effects & Interactions

Answer 4

Effects: Tremors, headaaches, nervousness, dizziness, dysrhythmias, chest discomfort, palpitations, nausea/vomiting, dry mouth

Interactions: Additive effects with TCAs, MAOIs, other sympathomimetics. Beta blockers may inhibit pulmonary effects, may potentiate diruetic hypokalemia

Question 5

Dosage and Administration

Answer 5

Adult: Respiratory distress: 2.5-5mg via nebulizer or 1-2 inhalations. Signs of bronchospasm: 5mg via neb. Repeat dose unlimited times as needed. Hyperkalemia: