Alcoholic Cirrhosis Of Liver

Question 1

What fiction does the liver provide

Answer 1

Stores glycogen
Produces hormones and proteins for blood clotting
Aiding removal of toxins
Produces bile

Question 2

What is cirrhosis

Answer 2

A progressive disease of the liver characterised by liver cell damage, scarring of liver tissue and abnormal liver architecture & function

Question 3

What are the 3 stages of cirrhosis

Answer 3

Fatty liver - liver cells replaced with larger fat cells (reversible)

Fibrosis - cell damage, repair can’t keep up and starts producing indigestible Collagen that stays and scars

Cirrhosis - loss of collagen, increasing damage to structure and function loss

Question 4

What stains are used to detect cirrhosis

Answer 4

Perl’s stain - stains iron (Prussian blue) in tissue that kills cells and is released when cells die
van Giesson’s stain - stains collagen (red) and hepatocytes yellow

Question 5

What does alcohol do to hepatocytes to cause cirrhosis

Answer 5

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