All Flashcards

0
Q

T(8:14)

A

Burkitts - cmyc:Ig. “Do you C MY Case of Burr?”

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1
Q

Drugs acting on microtubules

A
"The MicroTubule Growth Voiding Chemicals":
Thiabendazole
Mebendazole
Taxol
Griseofulvin
Vincristine/ Vinblastine
Colchicine
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2
Q

Chiari 1 vs 2

A

One=TONsils. Only use a syringe once.

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3
Q

Target cell etiology re

A

HALT said the hunter to his target: HbC dz, asplenia, Liver dz, thalassemia

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4
Q

Lead antidote

A

PEDS eat LEAD walls: penicillamine, edta, dimercaprol, succimer

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5
Q

Cyanide antidote

A

Never Try Huffing- Nitrite , thiosulfate, hydroxocobalamin

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6
Q

Serotonin syndrome components and causes

A
Causes TOTAL HARM:
Tramadol
Ondansetron
Triptans
Antidepressants
Linezolod

Hyperthermia
Autonomic instability (delirium)
Rigidity
Myoclonus

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7
Q

Small cell paraneoplastic conditions

A

Small Cell Lung cancer Sucks- SIADH, Cushings, Lambert Eatin, Subacute cerebellar degeneration

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8
Q

NRTIs

A

(nucleoside reverse transcriptase inhibitor mnemonic

LEADS To Z

Lamivudine
Emtricitabine
Abacavir
Didanosine

Tenofovir

Zidovudine

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9
Q

NNRTIs

A

NEeD- nevirapine, efavirenz, delavirdine

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10
Q

Which NRTI used during pregnancy

A

When you have a Zid use Zidovudine

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11
Q

Integrase inhibitors

A

Integrate- raltegravir, Elvitegravir

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12
Q

Bipolar treatment

A

CALm LoVE- Carbamazepine, atypical antidepressants, Lithium, Lamotrigine, Valproate

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13
Q

Lithium side effects

A
LMNOP- 
Lithium sode effects
Movement tremor
Nephrogenic diabetes insipidus
HypOthyroid
pregnancy problems
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14
Q

tPA antidote

A

Tranexamic acid
Plasminogen inhibitors
Aminocaproic acid

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15
Q

Myotonic dystrophy

A
Dystal weakness
Severe
Testicular atrophy
Reduced type 1 fibers
Optic cataracts
Protein kinase 
Hair loss
IQ low
Arrythmia,AD
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16
Q

Guillain barre

A
Ascending/autoimmune
Bilateral
Cytoalbumin dissociation
Demyelination
Endoneural inflammation
Flaccid paralysis
Guillain barre
Hyporeflexia
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17
Q

Prinzmetal

A

ST Elevation
Spasm-coronary
Tired/transient

Ergonovine diagnosis

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18
Q

Hemoglobin elecyrophoresis

A

“ASC before you GLU VALs LYpS”
HbA- glu
HbS- VAL
HbC-LYS

In order from most negative to least negative

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19
Q

Abd aortic aneurysm vs thoracic

A

AAA: atherosclerosis
TAA:hyperTension

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20
Q

Toxoplasmosis congenit

A

Three C’s: Chorioretinitis, cerebral calcifications, hydroCephalus

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21
Q

Toxoplasmosis

A

My Cats Eat Mice

Mono like illness
Chorioretinitis
Encephalitis
Mocarditis

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22
Q

Chagas dz

A

1) Trypansoma Cruzi - Chagas disease symptoms and cause:

“Tom Cruise is a huge ass (megacolon), who is pretty hard to swallow (megaesophagus), but he has a big heart (dilated cardiomyopathy) and he knows how to kiss red lips” (transmitted by Reduvid bug, aka kissing bug).

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23
Q

Cryptococcus transmission

A

Pigeon droppings- cryptococcus looks like a bird dropping

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24
Lateral pontine syndrome
Facial droop means the AICAs pooped.
25
Plummer vinson syndrome
The Plumber Vincent's wife has a sore red tongue (glossitis) and dysphagia (webs) from trying to swallow his big iron pipe
26
Urease positive bugs
``` CHuck norris hates PUNKSS Crytpococcus H Pylori Proteus Ureaadma Nocardia Klebsiella Staph Epidermidis Staph Saprophyticus ```
27
Causes of gastric acid release
High Gastric Acid Histamine H2 Gastrin Ach M3
28
Thrombotic thrombocytopenic purpura
Adam is a FAT RN ADAMTS13 deficiency F- fever A- hemolytic anemia (schistocytes on smear) T- thrombocytopenia R- renal failure N- neuro dysfunction (confusion, stupor, altered mental status)
29
Bosentan
ENdothelin ANtagonist
30
Foscarnet
FOScarnet: pyroFOSphate analog (chelates ca) CMV retinitis: C My Very Fastcar
31
Propionyl CoA derivatives
Put the PROP on the BOTM Bcaas Odd chain FAs Threonine Methionine
32
Long QT syndromes
Romano Ward: Romance a QT with your Heart WarD: AD Jervell and Lange Nielson: JeRvell: AR LONG QT and No Sound
33
Abetalipoproteinemia
AR AR, ataxia, acanthocytosis Retinitis pigmentosa, retardation, rbc shape
34
Measles prodrome
``` CCCK Cough Coryza Conjunctivitis Koplik Spots ```
35
Drugs causing hypothyroidism
``` LASH Lithium Amiodarone Sulfonamides Hypothyroid ```
36
Wilson disease
Copper is Hella BAD Ceruloplasmin decreased, Cirrhosis, Corneal deposits (kayser fleischer rings), Copper accumulation, Carcinoma (HCC) Hemolytic anemia Basal ganglia degeneration Asterixis Dementia, Dyskinesia, Dysarthria
37
Hemochromatosis
Can Cause Deposits And Hemosiderosis ``` Cirrhosis CHF Diabetes Atrophy of testicles Hemosiderin ```
38
Thiopental
``` FIRST LP fat Induction Rapid Skeletal muscle Thiopental Lipid soluble Potent ```
39
Lyme dz
FAKE a Key LYME pie Facial nerve palsy Arthritis Kardiac block Erythema migrans
40
Organisms not covered by cephalorpsorins
LAME Listeria Atypicals Mrsa Enterococci
41
Rash on palms and soles
You drive CARS with your palms and soles Coxsackie A Rocky mountain spotted fever Syphilis (2)
42
Rickettsial dz
Rickettsii (RMSF) on wRists Typhus on Trunk
43
Dantrolene
TROLLs make you Hot and Psychotic Treatment for : Malignant hyperthermia Neuroleptic malignant syndrome
44
Baclofen
GABAclofen- inhibits GABA at spinal cord BACKlofen- relaxes your back
45
Schizo disorders
SchizoiD: Distant (social withdrawal) SchizoTypal: magical Thinking Schizophreniform: a form of schizophrenia obly lasting 1-6 mos Schizophrenia: delusions, flat affect, etc SchizoAffective: bipolar or depressed affect plus psychosis
46
TGF B
To Grow Fibrosis Fibrosis and angiogenesis
47
Craniopharyngioma
C: children, calcifications, cysys R: Rathkes pouch derivative
48
Fomepizole
Fo Methanol Antidote for methanol or ethylene glycol poisoning
49
Sarcoidosis
``` SARCOID Schaumann bodoes ACE elevated Respiratory hilar adenopathy and fibrosis Ca elevated Ocular lesions Interstitial fibrosis Diabetes insipidus ```
50
CREST syndrome
``` Calcinosis and antiCentromere antibodies Raynaud phenomenon Esophageal dysmotility Sclerodactyly Telangiectasia ```
51
Apolipoproteins functions
Apo E mEdiates rEmnant uptake Apo C-II is a lipoprotein Cofactor Apo B 48 mediates chylomicron secretion (48 is micro) Apo B 100 binds LDL receptor Both triglyceride transporters contain ApoB
52
Caspofungin
No FUN IN a GLUed Wall Inhibits synthesis of B glucan in cell wall
53
Terbinafine
SQUATER Squalene epoxidase inhibitor
54
Drugs causing aplastic anemia
Cant Make New Blood Cells Properly ``` Carbamazepine Methimazole Nsaids Benzene Chloramphenicol Propylthiouracil ```
55
Drugs causing agranulocytosis
Drugs CCCrush Myeloblasts and Promyelocytes ``` Dapsone Clozapine Carbamazepine Colchicine Methimazole Propylthiouracil ```
56
Drugs causing hyperkalemia
``` KATS BANG K sparing diuretics ACEI tMP SMX Beta blockers ARBs NSAIDs Glycosides ```
57
Muscarinic antagonists
Inhibits Parasympathetic and Sweat Ipratropium Pirenzipime Atropine Scopolamine
58
Von Hippel Lindau
HHIPPEL ``` Hemangioblastoma HIF expression Increased Renal cell carcinoma Pheochromocytoma Port wine stain Eye dysfunction Liver, pancreas kidney cysts ```
59
Neurofibromatosis 1
CAFE SPOTS ``` Cafe au lait spots Axillary inguinal freckles Fibromas Eye lisch nodules Skeletal bowing Pheochromocytoma Optic tumor- gliomas ```
60
Sturge weber
STURGE ``` Sporadic/ port wine stain Tram track Ca/ Trigeminal Unilateral Retardation Gluacoma Epilepsy ```
61
Tuberous Sclerosis
HAMARTOMAS ``` Hamartoma in CNS Angiofibromas Mitral regurg Ash lead spots Rhabdomyoma Tuberous sclerosis Autosomal dOminant Mental retardation Angiomyolipima renal Seizures ```
62
Osler weber rendu
TEACH ``` Telangiectasias Epistaxis AV malformations Cerebral abscess Hemorrhages ```
63
Wiskott aldrich syndrome
WATEr ``` Wiskott Aldrich Thrombocytopenic purpura Eczema Recurrent infections ```
64
Lesch Nyhan
HGPRT ``` Hyperuricemia Gout Pissed off Retardation DysTonia ```
65
Propylthiouracil
PTU blocks Peripheral conversion. Used in Pregnancy
66
Bones ofwrist
So Long to Pink Here Comes The Thumb ``` Scaphoid Lunate Triquetrum Pisiform Hamate Capitate Trapezoid Trapezium ```
67
PAS stain
Dont TRYP PAS me the WHIP PAS positive: alpha 1 antiTRYPsin deficiency and WHIPPles dz
68
Enzymes in the mitochondria only
BOAT as in the mitochondria looks like a boat Beta oxidation of fatty ocids Oxidative phosphorylation Acetyl CoA production TCA cycle
69
Enzymes in mitochondria and cytoplasm
HUGs take two(both) Heme synthesis Urea cycle Gluconeogenesis
70
Amino acid losing diseases
Im a FAN of all aa but i HART neutral aa Fanconi syndrome. Loss of all aa Hartnup disease. Loss of neutral aa (tryp)
71
Drugs causing disulfiram reaction
Scotch and Corona Make me Gag and Puke ``` Sulfonylureas Cephalosporins Metronidazole Griseofulvin Procarbazine ```
72
Drugs causing pulmonary fibrosis
Breathing Air Badly from Medications Bleomycin Amiodarone Busulfan Methotrexate
73
Buproprion
SOS (indications) ABUSE (contraindications) Smoking Obesity Sexual side effects from other drugs Anorexia BUlemia SEizures
74
Drugs causing seizures
With seizures I BITE My tongue INH Bupropion Imipenem Tramadol Enflurane Metoclopramide
75
Metoclopramide
DANMET- dopamine antagonist metoclopramide Motility Emesis Tone dOpamine antagonist
76
Drug metabolism in elderly
Old people have GAS They retain phase 2 conjugation (glucuronidation, acetylation, sulfation) and lose phase 1 (cyp 450)
77
Fenoldopam
Old PAM is A DR Antihypertensive Dopamine D1 agonist Renal vasodilation
78
Valproic acid uses
Crap Seizures Make me Bite my Tongue ``` Complex Simple Absence Myoclonic Bipolar disprder Tonic clonic ```
79
Valproic acid side effects
VALPRoaTe ``` Vomiting Alopecia Liver toxicity Pregnancy contraindication Retain fat Tremor ```
80
Carbamazepine uses
CBZ CN V neuralgia Bipolar Zeisures
81
Carbamazepine side effects
A PLASTIC LIVER SITS in my CAR aplastic anemia Liver tox SIADH Carbamazepine
82
Phenytoin side effects
Steven HIRed a PHONY GINGer TERrorist to ATAck NY eNEMies ``` Stevens johnson syndrome Hirsutism Phenytoin Gingival hyperplasia Teratogen Ataxia Nystagmus Anemia megaloblastic ```
83
Beurgers dz
Burger SCRAPS ``` Segmental thrombosing Claudication Raynauds Associated woth smoking Pain Superficial nodular phlebitis ```
84
Churg Strauss
CHange the PPAGE CHurg Strauss ``` Palpable purpura P ANCA Asthma Granulomas Eosinophilia ```
85
Henoch schonlein purpura
PAPAH Purpura Abd pain Arthralgias Hematuria
86
Thyroid papillary carcinoma pathology
Orphan Annies moma and Papa left so now she sleeps on ground glass Orphan annie nuclei PsaMOMA bodies Papillary Ground glass nucleus due to dispersed chromatin
87
Medullary thyroid carcinoma
Medam: medullary, amyloid stroma Med Men RETired: medullary, MEN 2, RET mutations
88
Function of MYC
Read the SCRIPT with the MYC Trxn activators
89
Dermatomyositis
Wear a SHAWL when you GET ON the HELIcopter and say Hi to the MECHANIC shawl and face rash Gottron papules Heliotrope rash around mouth Mechanics hands
90
Renal immune complex deposition
1 Male Performer Does Props on Bottom 2 Male performers in middle Male Acrobat Performs Splits on Top Subendothelial: type 1 MPGN, DPGN Intramembranous: type 2 MPGN Subepithelial: MGN, APSGN
91
Types of stomach cancer
Diffuse: Dont DIFFUSE the situation by giving her a RING. Her stomach will get THICK and LEATHERY. - signet rings cells, stomach wall is gross and leatheru, diffuse Intestinal: think H pylori- ulcerated
92
Lichen Planus
6 P's Pruritic Purple Polygonal planar papules Plaques On wrost hands and trunk
93
Erythema multiforme
Targets HSV Target lesions in HsV
94
Interferon alpha and beta
Interfere with viruses Prime local cells for viral infection by increasing RNAase L and protein kinase resulting in apoptosis of infected cells
95
Neuromuscular blocking agents
Suc Deep No Cur Succinylcholine is depolarizing Atracurium is nondepolarizing
96
Chediak higashi syndrome
CHINA ``` Chediak Higashi Infections- defective phagosome lysosome fusion Neuropathy - nystagmus and peripheral Albinism- abnl melanin storage ```