All Topics Flashcards
Normal ph of the vagina
3.8-4.2
Flutamide
- Moa
- adverse effects
- antiandrogen
- most common ae: dry skin
- associated with hepatitis
“FLUtamide Gives the Liver the FLU and Cracked Skin too”
Most common cause of hemolytic disease of newborn
ABO incompatibility
- 1st preg is worst
- neonatal jaundice
- type A in newborn usually
- IgM so no hydrops fetalis like with Kell, Duffy, Kidd Ab
“ABO Must stay ABOut and Away from the baby”
Most common cause of maternal-fetal group incomptability
ABO incompatibility
- 1st preg is worst
- neonatal jaundice
- type A in newborn usually
- IgM so no hydrops fetalis like with Kell, Duffy, Kidd Ab
“ABO Must stay ABOut and Away from the baby”
Most common type of nonproliferative breast lesion
Breast cyst
5 Causes of bloody nipple discharge
Clue: TIIPP of the breast
Trauma Infection - mastitis Intraductal carcinome Papilloma Pagets disease
“Bleeding at the TIIPP of the breast”
Osteopenia definition
Between -1 to -2.5
Osteoporosis and severe osteoporosis definition
Osteoporosis below -2.5
Severe osteoporosis below -2.5 + fracture
Hormons from anterior pituitary
Clue: FLATPG
FSH LH ACTH TRH Prolactin GnRH
“FLAT PG”
Hormones of the Posterior pituitary
Oxytocin ADH
- same alpha subunit
1st sign of sheehan syndrome
Failure of lactation
Name 3 primary estrogens of the body and its origin
Clue: One Two Three
estrONE - one body menopause
estraDIol - two ovaries
esTRIol - three mom/baby/placenta or trimesters
Different between Duffy Fya and Duffy Fyb
Fya - Awful like “Fire” causing erythroblastosis fetalis
Fyb - Better so baby lives
Enzyme that convertes 17 hydroxyprogesterone to androstenedione
21 hydroxylase
- if deficient, get inc steroid production —> virilization, CAH
Organ that makes DHEA
Adrenal glands
Enzyme that converts testosterone to dihydrotestosterone
5 alpha reductase
- if deficient, no external male genitalia
Enzyme that converts testosterone to estrogen
Aromatase
- inhibitors: letrozole (for fibroids, endometriosis) and anastrozole (for breast cancer)
Ag that cause erythroblastosis fetalis
Kell - Kills
Kidd - Kills
Duffy fya - Dies
Ag that cause severe hemolytic disease
EDC and Kell
“Kell Kills the EDC baby”
Enzyme that converts 17 hydroxypregnenolone to 17 hydroxyprogesterone
17 alpha hydroxylase
- if deficient, inc in mineralocorticoids —> HTN, high Na
Inherited thrombophilias and mode of inheritance
Clue: Mother of V PACS
Factor V Prothrombin 3 G20210A Antithrombin 3 Protein c Protein s MTHFR - all AD except for MTHFR which is AR “Mother of V-Dominant-PACS”
Complication with inherited thrombophilia
DVT/PE
Complication w acquired thrombophilia
Stillbirth
Different treatments for lichen planus
Cyclosporine Systemic corticosteroids Hydroxyquinoline Methotrexate Clobetasol
