Allergic Reaction Directive

Question 1

What are the indications under this directive?

Answer 1

Exposure to a probable allergen;
AND
Signs and/or symptoms of a moderate to severe allergic reaction (including
anaphylaxis).

Question 2

What are the conditions for EPI?

Answer 2

For anaphalaxis only.

Question 3

Contraindications for EPINEPHrine?

Answer 3

EPINEPHrine
Allergy or sensitivity to
EPINEPHrine

Question 4

Treatment for EPI?

Answer 4

Route: IM
Concentration: 1 mg/mL = 1:1,000
Dose: 0.01mg/ kg*
Max. single dose: 0.5mg
Dosing interval: Minimum 5 min
Max. # of doses : 2

Question 5

Conditions for diphenhydrAMINE?

Answer 5

≥ 25 kg

Question 6

Contraindications for diphenhydrAMINE?

Answer 6

Allergy or sensitivity to
diphenhydramine.

Question 7

Tx for diphenhydramine?

Weight ≥ 25 kg to < 50 kg

Answer 7

Route : IV/IM
Dose: 25 mg
Max. single dose: 25 mg
Dosing interval: N/A
Max. # of doses: 1

Question 8

Tx for diphenhydramine?

Weight ≥ 50kg

Answer 8

Route : IV/IM
Dose: 50 mg
Max. single dose: 50 mg
Dosing interval: N/A
Max. # of doses: 1

Question 9

What are clinical considerations under this directive?

Answer 9

EPINEPHrine administration takes priority over IV access.