Allergy & Immunology Flashcards by Sariya Khan

Q

Co-stimulatory effect on T cells

A

IL-1

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Q

Enhances antigen presentation

A

IL-1

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Q

Primary T-cell growth factor

A

IL-2

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Q

B-cell and NK-cell growth factor

A

IL-2

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Q

Required for T-regulatory cell function and survival

A

IL-2

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Q

Mast cell growth factor

A

IL-3

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Q

Multicolony-stimulating factor

A

IL-3

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Q

T-cell growth factor

A

IL-4

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Q

Enhances IgE synthesis

A

IL-4

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Q

Enhances B-cell differentiation

A

IL-4

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Q

Mast cell growth (2)

A

IL-4, IL-9

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Q

Enhances eosinophil differentiation

A

IL-5

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Q

Enhances immunoglobulin synthesis (3)

A

IL-5, IL-6, IFN-gamma

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Q

Enhances IgA synthesis (2)

A

IL-5, IL-6

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Q

Antiviral activity

A

IL-6

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Q

Hematopoietic effects

A

IL-6

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Q

Enhances growth of pre-T cells

A

IL-7

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Q

Neutrophil-activating protein

A

IL-8

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Q

T lymphocyte and neutrophil chemotactic factor

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A

IL-8

Q

Acts in synergy with IL-_ to induce IgE production

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A

IL-9, acts in synergy with IL-4

Q

Cytokine synthesis inhibitory factor

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A

IL-10

Q

Suppresses macrophage function

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A

IL-10

Q

Enhances B-cell growth (2)

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A

IL-10, IL-13

Q

Inhibits IL-12 production

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A

IL-10

Suppresses inflammation at mucosal surfaces

IL-10

NK cell stimulatory factor

IL-12

Cytotoxic lymphocyte maturation factor

IL-12

Enhances IFN-gamma synthesis (2)

IL-12, IL-18

Inhibits IL-4 synthesis

IL-12

Enhances IgE synthesis

IL-13

Inhibits macrophage activation

IL-13

Causes airway hyperreactivity

IL-13

Induces IL-1B and IL-6 synthesis

IL-17

Important in fungal infections

IL-17

Macrophage activation

IFN-gamma

Inhibits IgE synthesis

IFN-gamma

Inhibits T-cell and B-cell proliferation and activation

TGF-B

Induces T regulatory cells

TGF-B

Chemokine for monocytes (2)

RANTES, IP-10

Chemokine for T cells (2)

RANTES, MIP-1a

Chemokine for Eosinophils (2)

RANTES, Eotaxin 1/2/3

Enhances differentiation of CD4+ T cells

MIP-1a

Chemokine for basophils

Eotaxin 1/2/3

Chemokine for Th2 cells

Eotaxin 1/2/3

Chemokine for activated T cells

IP-10

Chemokine for NK cells

IP-10