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NUTR 445 > ALLOSTERIC REGULATION OF ENZYMES IN RESPONSE TO CELLULAR ENERGY STATUS > Flashcards

ALLOSTERIC REGULATION OF ENZYMES IN RESPONSE TO CELLULAR ENERGY STATUS Flashcards

(46 cards)

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1
Q

Low Cellular Energy: ↑ AMP, ↓ ATP, ↓ citrate, ↓ acetyl-CoA: Regulated Enzyme?

A

↑ Phosphofructokinase

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2
Q

Low Cellular Energy: ↑ AMP, ↓ ATP, ↓ citrate, ↓ acetyl-CoA: Metabolic Response?

A

↑ Glycolysis

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3
Q

Low Cellular Energy: ↓ ATP, ↓ acetyl-CoA: Regulated Enzyme?

A

↑ Pyruvate kinase

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4
Q

Low Cellular Energy: ↑ ADP, ↑ pyruvate: Regulated Enzyme?

A

↑ Pyruvate dehydrogenase

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5
Q

Low Cellular Energy: ↓ ATP, ↓ acetyl-CoA: Metabolic Response?

A

↑ TCA cycle

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6
Q

Low Cellular Energy: ↑ ADP: Regulated Enzyme?

A

↑ Isocitrate dehydrogenase

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7
Q

Low Cellular Energy: ↑ AMP: Regulated Enzyme?

A

↓ Fructose-1,6-bisphosphatase

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8
Q

Low Cellular Energy: ↑ AMP: Metabolic Response?

A

↓ Gluconeogenesis

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9
Q

Low Cellular Energy: ↓ Malonyl-CoA: Regulated Enzyme?

A

↑ Carnitine acyltransferase I

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10
Q

Low Cellular Energy: ↓ Malonyl-CoA: Metabolic Response?

A

↑ Fatty acid β-oxidation

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11
Q

Abundant Cellular Energy: ↑ ATP, ↑ citrate: Regulated Enzyme?

A

↓ Phosphofructokinase

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12
Q

Abundant Cellular Energy: ↑ ATP, ↑ citrate: Metabolic Response?

A

↓ Glycolysis

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13
Q

Abundant Cellular Energy: ↑ ATP: Regulated Enzyme?

A

↓ Isocitrate dehydrogenase

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14
Q

Abundant Cellular Energy: ↑ ATP: Metabolic Response?

A

↓ TCA cycle

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15
Q

Abundant Cellular Energy: ↑ ATP: Regulated Enzyme?

A

↓ α-Ketoglutarate dehydrogenase

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16
Q

Abundant Cellular Energy: ↑ Acetyl-CoA: Regulated Enzymes?

A

↑ Pyruvate carboxylase

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17
Q

Abundant Cellular Energy: ↑ Acetyl-CoA: Metabolic Response?

A

↑ Gluconeogenesis

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18
Q

Abundant Cellular Energy: ↑ Citrate: Regulated Enzyme?

A

↑ Fructose-1,6-bisphosphatase

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19
Q

Abundant Cellular Energy: ↑ Citrate: Regulated Enzyme?

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A

↑ Acetyl-CoA carboxylase

20
Q

Abundant Cellular Energy: ↑ Citrate: Metabolic Response?

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A

↑ Fatty acid synthesis

21
Q

Abundant Cellular Energy: ↑ Malonyl-CoA: Regulated Enzyme?

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A

↓ Carnitine acyltransferase I

22
Q

Insulin: Gluconeogenesis

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A

Decrease in the liver

23
Q

Glucagon: Gluconeogenesis

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A

Increase in the liver

24
Q

Glucagon: Glycogenolysis

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A

Increase in the liver

25
Epinephrine: Glycogenolysis
Increase in the liver and skeletal muscle
26
Insulin: Glycogenesis
Increase in the liver and skeletal muscle
27
Glucagon: Glycogenesis
Decrease in the liver
28
Epinephrine: Glycogenesis
Decrease in the liver and skeletal muscle
29
Insulin: Glycolysis
Increase in the liver and skeletal muscle
30
Glucagon: Glycolysis
Decrease in the liver
31
Epinephrine: Glycolysis
Increase in the skeletal muscle
32
Insulin: Glucose uptake by GLUT4
Increase in the liver, heart, and skeletal muscle
33
Glucagon: Fatty Acid Oxidation
Increase in the liver
34
Insulin: Fatty Acid Synthesis
Increase in the adipose tissue, skeletal muscle, and the liver
35
Glucagon: Fatty Acid Synthesis
Decrease in adipose tissue and the liver
36
Epinephrine: Fatty Acid Synthesis
Decrease in the adipose tissue, skeletal muscle, and the liver
37
Insulin: Fatty acid uptake from plasma lipoproteins
Decrease in the skeletal muscle and adipose tissue
38
Epinephrine: Fatty acid uptake from plasma lipoproteins
Increase in the skeletal muscle
39
Insulin: Triacylglycerol Synthesis
Increase in the adipose tissue
40
Glucagon: Triacylglycerol Synthesis
Decrease in the liver
41
Insulin: Triacylglycerol Breakdown (Lipolysis)
Decrease in the adipose tissue
42
Glucagon: Triacylglycerol Breakdown (Lipolysis)
Increase in the adipose tissue
43
Epinephrine: Triacylglycerol Breakdown (Lipolysis)
Increase in the adipose tissue and the skeletal muscle
44
Insulin: Protein Synthesis (Translation)
Increase in the skeletal muscle and the liver
45
Insulin: Protein Breakdown (Proteolysis)
Decrease in the skeletal muscle
46
Glucagon: Ketone Body Production
Increase in the liver

NUTR 445 (2 decks)

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