ALU 301 Chapter 3 Quiz Flashcards

1
Q

The triad of positive rheumatoid factor, enlarged spleen, and neutropenia is:

  • Caplan’s syndrome
  • Felty’s syndrome
  • Sjogren’s syndrome
  • Still’s disease
A

Felty’s syndrome

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2
Q

All of the following statements regarding laboratory testing on individuals with rheumatoid arthritis are correct EXCEPT:

  • globulins are often elevated
  • cholesterol may be low in late stage disease
  • The inflammatory process may elevate HDL
  • low albumin is a poor prognostic indicator
A

The inflammatory process may elevate HDL

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3
Q

The joints most commonly affected by rheumatoid arthritis include all of the following EXCEPT:

  • elbows
  • knees
  • shoulders
  • hips
A

hips

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4
Q

All of the following laboratory tests are commonly used for the diagnosis and monitoring of rheumatoid arthritis EXCEPT:

  • gamma-glutamyltransferase (GGT)
  • rheumatoid factor
  • anti-cyclic citrullinated peptide (anti-CCP)
  • C-reative protein (CRP)
A

GGT

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5
Q

The hallmark of current therapy for rheumatoid arthritis is the use of:

  • non-steroidal anti=inflammatory drugs (NSAID’s)
  • cyclooxygenase inhibitors (COXIB’s)
  • disease modifying anti-rheumatic drugs (DMARD’s)
  • corticosteroids
A

disease modifying anti-rheumatic drugs - DMARD’s)

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6
Q

A chronic inflammatory polyarthritis of unknown etiology is:

  • viral arthritis
  • rheumatoid arthritis
  • gouty arthritis
  • osteoarthritis
A

rheumatoid arthritis

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7
Q

All of the following are possible etiologies of rheumatoid arthritis EXCEPT:

  • genetics
  • infection
  • cigarette smoking
  • oral contraceptives
A

oral contraceptives

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8
Q

Which of the following medications are used to slow the progression of joint erosion in rheumatoid arthritis?

A - Biologics
B - disease modifying anti-rheumatic drugs (DMARD’s)
C- non-steroidal anti-inflammatory drugs (NSAID’s)

A and B only
A and C only
B and C only
A, B, and C are all correct

-

A

A and B only

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9
Q

The most probable theory is that rheumatoid arthritis is the result of:

  • infection
  • smoking
  • multiple gene dysfunction
  • decaffeinated coffee consumption
A

multiple gene dysfunction

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10
Q

Rheumatoid arthritis commonly affects all of the following joints EXCEPT:

  • shoulders
  • neck
  • ankles
  • wrists
A

neck

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11
Q

Initial assessment of rheumatoid arthritis includes which of the following?

A - blood chemistries
B - radiographs of affected joints
C - anti-cyclic citrullinated peptide antibody (ACPA)

A only is correct
A and B are correct
B and C are correct
A, B, and C are correct

A

A, B, and C are all correct

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12
Q

Which of the following labs are typical findings in those with rheumatoid arthritis?

A - elevated white blood count
B - elevated globulins
C - mild thrombocytosis

A and B only are correct
A and C are correct
B and C are correct
A, B, and C are all correct

A

B and C are correct

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13
Q

The most sensitive tool for joint assessment is:

  • xray
  • MRI
  • ultrasound
  • CT scan
A

MRI

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14
Q

The medical treatment considered to be the gold standard for moderate to severe rheumatoid arthritis is:

  • methotrexate (MTX)
  • sulfasalazine
  • hydroxychloroquine
  • leflunomide
A

methotrexate

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15
Q

Which of the following accounts for the greatest number of deaths associated with rheumatoid arthritis?

  • infection
  • renal disease
  • pulmonary disease
  • cardiovascular disease
A

cardiovascular disease

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16
Q

Which of the following statements regarding synovial joints is/are correct?

A- it is comprised of two bones held together by a fibrous capsule
B - the synovium provides nutrients to avascular cartilage
C - synovial fluid between the bones allows frictionless movement of the joint

A only is correct
A and C are correct
B and C are correct
A, B, and C are all correct

A

A, B, and C are all correct

17
Q

Elevated rheumatoid factor (RF) can be seen in all of the following diseases EXCEPT:

  • Sjogren’s syndrome
  • mixed connective tissue disease
  • systemic lupus erythematous (SLE)
  • osteoarthritis
A

osteoarthritis

18
Q

Mild rheumatoid arthritis is characterized by all of the following EXCEPT:

  • joint pain
  • mild morning stiffness
  • elevated ESR
  • extra articular manifestations
A

extra articular manifestations

19
Q

Which of the following cells infiltrate the subintimal area of the synovium in those with rheumatoid arthritis?

A- T-lymphocytes
B - macrophages
C - cytokines

A only is correct
A and B are correct
B and C are correct
A, B, and C are all correct

A

A and B are correct

20
Q

The condition that is the result of inflammation of the synovial tissue, microvascular injury and the profound proliferation and hypertrophy of the synovial tissue is:
- pannus formation
- morning stiffness
- vasculitis
- osteoporosis

A

pannus formation