Alzheimer's

Question 1

What happens to those with Alzheimer’s disease?

Answer 1

Amyloid plaques live in extracellular places around neurons, inside neurons neurofibrillary. These tangles kill neurons in the brain. Depletion of brain

Question 2

What can you do with amyloid plaques?

Answer 2

Stain aggregate lumps of amyloid protein.

Question 3

What causes Alzheimer’s disease?

Answer 3

Mutation

Question 4

What do beat amyloids do?

Answer 4

Combine-protein sticks out and forms plaque group of beta with antennae.

Question 5

What chromosome is it found on?

Answer 5

Chromosome 21
Down syndrome also on chromosome 21
150%

Question 6

What else is there other than tangles?

Answer 6

microtubules, part of the cytoskeleton.

Question 7

What is AcHe?

Answer 7

Enzyme that breaks down acetylcholine.

Question 8

What is treatment focused on?

Answer 8

Initially decline of acetycholine - cholinergic agonist only works early stages. Drugs include Chlorestare inibitors, revagistine (exelern) and galatamine (bemytrril)

Question 9

What does Ebixa do?

Answer 9

NMDA receptor against blocks memantine. May stop gluatminergic induced neurotoxicity.

Question 10

What effect have stem cells had?

Answer 10

Slight improvement.