Amines Flashcards
(14 cards)
what can primary amines act as
Bronstead-lowry bases
(lone pair canaccept H+)
why are primary amines better bases than ammonia
the alkyl groups push electrons towards N
why are secondary amines better bases than primary
they have more alkyl groups so e- pushed more towards N
(inductive effect)
acid plus amine makes
ammonium salt
what does using an excess of ammonia ensure when making amines
maximum amount of primary amine formed-
what will ensure the formation of a quaternary salt
using an excess of the halogenoalkane
what can quaternary ammonium salts be used as
cationic surfactants
in conditioners etc.
reduce surface tension of water
what is a better method of producing primary amines
convert haloalkane to nitrile
reduce nitrile to amine
with H2 and a Ni catalyst
disadvantage of the nitrile method of producing primary amines
low yield as two step process
KCN is toxic
repeating units of terelyene, nylon 6,6 and Kevlar
how are amino acids located on a chromatogram
developing agents such as ninhydrin or UV light
how do enzymes act as catalysts
they have a stereospecific active site which is complementary to the substrate
only complementary to one entaniomer
structure of phosphate ion and 2 deoxyribose
how does cisplatin work
ligand substitution on DNA
bond formed between platinum and nitrogen atom on guanine
