Amines Flashcards
1
Q
State why the the amine formed from nucleophilic sub is contaminated with other amines. Suggest how the reaction conditions could be modified to minimise contamination (other products)
A
1 Further substitution occurs 2 Use excess nucleophile e.g NH3
2
Q
Why can’t bromobenze undergo nucleophilic sub?
A
Delocalised system of benzene repels nucleophiles
3
Q
Why is methylamine a stronger base than ammonia
A
- CH3 pushes electrons to N
- So the electron density on N increases
- Lone pair on N more available so can attracts and accept H+
4
Q
Why is a 1• the major product when ammonia is in excess for the reaction with haloalkane
A
- Further substitution prevented so 2• or 3• amine not made
- Because ammonia is more likely to react with the haloalkane rather than the amine product
- All the haloalkane is used up
5
Q
Explain why the melting point of aminoethanoic acid is much higher than that of hydroxyethanoic acid, HOCH2COOH
A
- ionic bonding in aminoethanoic acid
- stronger attractions than Hydrogen bonding in hydroxyethanoic
