Amino Acids Flashcards
(46 cards)
Zwitterions
molecules that have both a positive and negative charge, the overall charge is neutral
Amino Acid Titration Curve
shows pH dependance of the charge of an amino acid,
pH on x axis
net charge on y axis
pI (isoelectric point)
the pH at which an amino acid or protein has not net charge,
calculating pI value
average the pka values of the carboxyl and amino groups,
ionizable amino acids
aspartic acid (Asp), glutamic acid (Glu), lysine (Lys), arginine (Arg), histidine (His), cystine (Cys),
Peptide Bond Formation
condensation reaction between carboxyl group of one amino acid and amino group of another amino acid, with the release of a water molecule,
Reverse of Peptide Bond formation
hydrolysis reaction through the addition of a water molecule, releases individual amino acids,
N-terminus
end of the chain with a free amino group, peptide chain numbering starts there, affects molecule polarity,
C-terminus
end of the chain that has a free carboxyl group, affects molecule polarity,
Amino Acids
building blocks of polypeptides, 9 essential amino acids,
Amino Acid 1
Valine
val
V
essential
non-polar
AA general structure
carboxylic acid + amino group with an R group, the R group classifies the amino acid
Amino Acid 2
Alanine
ala
A
dispensable
non-polar
Amino Acid 3
Isoleucine
ile
I
essential
non-polar
Amino Acid 4
Arginine
arg
R
conditional
+charged
Amino Acid 5
Serine
set
S
dispensable
polar
Amino Acid 6
Histidine
his
H
essential
+charged
Amino Acid 7
Proline
pro
P
conditional
non-polar
Amino Acid 8
Glycine
gly
G
conditional
non-polar
Amino Acid 9
Methionine
met
M
essential
non-polar
Amino Acid 10
Lysine
lys
K
essential
+charged
Amino Acid 11
Leucine
leu
L
essential
non-polar
Amino Acid 12
Glutamine
gln
Q
conditional
polar
Amino Acid 13
Glutamate
glu
E
dispensable
-charged