Amino Acids Flashcards

(46 cards)

1
Q

Zwitterions

A

molecules that have both a positive and negative charge, the overall charge is neutral

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2
Q

Amino Acid Titration Curve

A

shows pH dependance of the charge of an amino acid,
pH on x axis
net charge on y axis

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3
Q

pI (isoelectric point)

A

the pH at which an amino acid or protein has not net charge,

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4
Q

calculating pI value

A

average the pka values of the carboxyl and amino groups,

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5
Q

ionizable amino acids

A

aspartic acid (Asp), glutamic acid (Glu), lysine (Lys), arginine (Arg), histidine (His), cystine (Cys),

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6
Q

Peptide Bond Formation

A

condensation reaction between carboxyl group of one amino acid and amino group of another amino acid, with the release of a water molecule,

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7
Q

Reverse of Peptide Bond formation

A

hydrolysis reaction through the addition of a water molecule, releases individual amino acids,

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8
Q

N-terminus

A

end of the chain with a free amino group, peptide chain numbering starts there, affects molecule polarity,

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9
Q

C-terminus

A

end of the chain that has a free carboxyl group, affects molecule polarity,

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10
Q

Amino Acids

A

building blocks of polypeptides, 9 essential amino acids,

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11
Q

Amino Acid 1

A

Valine
val
V
essential
non-polar

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11
Q

AA general structure

A

carboxylic acid + amino group with an R group, the R group classifies the amino acid

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12
Q

Amino Acid 2

A

Alanine
ala
A
dispensable
non-polar

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13
Q

Amino Acid 3

A

Isoleucine
ile
I
essential
non-polar

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14
Q

Amino Acid 4

A

Arginine
arg
R
conditional
+charged

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15
Q

Amino Acid 5

A

Serine
set
S
dispensable
polar

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16
Q

Amino Acid 6

A

Histidine
his
H
essential
+charged

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17
Q

Amino Acid 7

A

Proline
pro
P
conditional
non-polar

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18
Q

Amino Acid 8

A

Glycine
gly
G
conditional
non-polar

19
Q

Amino Acid 9

A

Methionine
met
M
essential
non-polar

20
Q

Amino Acid 10

A

Lysine
lys
K
essential
+charged

21
Q

Amino Acid 11

A

Leucine
leu
L
essential
non-polar

22
Q

Amino Acid 12

A

Glutamine
gln
Q
conditional
polar

23
Q

Amino Acid 13

A

Glutamate
glu
E
dispensable
-charged

24
Amino Acid 14
Cysteine cys C conditional polar
25
Amino Acid 15
Threonine the T essential polar
26
Amino Acid 16
Aspartate asp D dispensable -charged
27
Amino Acid 17
Asparagine asn N dispensable polar
28
Amino Acid 18
Tryptophan trp W essential non-polar
29
Amino Acid 19
Tyrosine tyr Y conditional polar
30
Amino Acid 20
Phenylalanine phe F essential non-polar
31
Acidic Amino Acids
aspartate (D) and Glutamate (E)
32
Basic Amino Acids
Lysine (K), Arginine (R), Histidine (H)
33
Nonpolar Amino Acids
Glycine, Alanine, Valine, Leucine, Isoleucine, Proline, Methionine, hydrophobic,
34
Polar Amino Acids
Threonine, Tyrosine, Serine Cystine, Asparagine, Glutamine, hydrophilic,
35
Aromatic Amino Acids
tryptophan (W), tyrosine (Y), Phenylalanine (F), histidine (H), transmembrane proteins
36
Side Chain pka ASP
3.5
37
Side Chain pka GLU
4
38
Side Chain pka LYS
10.5
39
Side Chain pka ARG
12.5
40
pH>pI
negative charge
41
Side Chain pka HIS
6
42
pH
positive charge
43
Each Day Call Me When You're Free Kindly Rhyming Happily Quickly Now Sing Truthfully Gleefully And Vehemently I Love Psychology
Glutamate (acid) Aspartate (acid) Cysteine (sulfur) Methionine (sulfur) Tryptophan (aromatic) Tyrosine (aromatic) Phenylalanine (aromatic) Lysine (basic) Arginine (basic) Histidine (basic) Glutamine (polar) Asparagine (polar) Serine (polar) Threonine (polar) Glycine (non-polar) Alanine (non-polar) Valine (non-polar) Isoleucine (non-polar) Leucine (non-polar) Proline (non-polar)
44
Glutamine Q mnemonic
glutamine call is Q tamine
45