Amino Acids

Question 1

Peptide bond formation mech

Answer 1

See image

Question 2

A peptide bond forms what?

Answer 2

An amide bond

Question 3

What stabilizes the peptide bond?

Answer 3

The resonance delocalization found between the electrons of the nitrogen and the carbonyl oxygen.

Question 4

What confirguation is a peptide bond?

Answer 4

Planar. The double bond resonance gives a rigid structure.

Question 5

What is a non-specific way to cleave a peptide bond?

Answer 5

Acid hyrdolysis (strong acid + heat)

Question 6

What is a specific way of cleaving a peptide bond?

Answer 6

Proteolysis (Enzymes called proteases)

Question 7

Amine vs. Amide?

Answer 7

Amine = Nitrogen on an alkane. Amide = Nitrogen on a carboxcylic acid

Question 8

Negatively charged amino acids (Full name + abbreviations)

Answer 8

Aspartic Acid (Asp/D), Glutamic Acid (Glu/E)

Question 9

Positively charged amino acids (Full name + abbreviations)

Answer 9

Lysine (Lys/K), Arginine (Arg/R), Histidine (His/H)