Aminosalicylate Drugs Flashcards
1
Q
Name some aminosalicylate drugs?
A
Sulphasalazine
Mesalazine
Olsalazine
2
Q
How do they work?
A
It is not fully understood but it is thought that they inhibit prostaglandin synthesis.
3
Q
What are some side effects of sulphasalazine?
A
- Rash
- Oligospermia
- Heinz Body Anaemia
- Megaloblastic anaemia.
4
Q
What is 7 times more common in mesalazine than sulfasalazine?
A
Pancreatitis
5
Q
What are some side effects of Mesalazine?
A
- GI UPset
- Headache
- Agranulocytosis
- Pancreatitis
- Interstitial nehpritis
