Anaesthetics Flashcards
(62 cards)
What do inotropes do?
increase myocardial contractility to increase cardiac output
What do vasopressors do?
increase vasoconstriction leading to increased SVR and BP
What type of receptor are adrenergic receptors?
G-protein coupled receptors
What do alpha 1 receptors cause?
smooth muscle contraction
Where are beta 1 receptors located?
heart
Where are beta 2 receptors located?
blood vessels
Which receptor does Noradrenaline work on?
alpha 1
Which receptor does Adrenaline work on?
low doses - beta
high doses - alpha
What receptors does Dobutamine work on? What does it cause?
beta 1 to increase heart rate but beta 2 to decrease SVR therefore BP
What do beta 2 receptor agonists cause?
vasodilation
What is the dosage of propofol?
1.5-2.5mg/kg
What does propofol do to BP and HR?
marked drop in both
What is the main indication for thiopentone?
RSI
What are the benefits of thiopentone?
antiepileptic properties and neuroprotective
What does thiopentone do to HR and BP?
increases HR but drops BP
When is thiopentone contraindicated?
porphyria
What is the dosage of ketamine?
1-1.5mg/kg
What does ketamine do to HR and BP?
increases both
What is the dosage of etomidate?
0.3mg/kg
Which induction agent has the lowest incidence of hypersensitivity?
etomidate
Which induction agent causes bronchospasm?
thiopentone
Which induction agent can cause adreno cortical suppression?
etomidate
Which muscle relaxant is depolarising?
suxamethonium
Which muscle relaxant is used in RSI?
suxamethonium