Analgeics Flashcards
(24 cards)
prostaglandins
enzymes that lead to pain and inflammation
COX enzymes
-COX 1: in tissue and cells (contious)
-COX 2: inactive until pain and inflammation occur
NSAIDS: anti-prostagladins
-M: meloxicam
-I: ibuprofen
-I: indomethacin
-C: celecoxib
-K: ketorolac
Salicylate: Aspirin
- anti-prostaglandin
- ant-coagulant
- anti-pyretic
- analgesic
- ant-inflammatory
AE of Aspirin
-risk for bleeding, renal toxcity, dizzy
Nursing Implications of Aspirin
-Avoid kids
-Don’t crush/chew
-Max dose of 8,000 (325 for pain 81 for blood thinner)
-Monitor for allergies/bleeding
Non-Narc: Acetaminophen
- acts on hypothalamus to increase sweating and lower pain
-anagleisc and anti-pyretic
AE of Acetaminophen
-hepatox and renal failure
Nurse Implications
-look for rash
-monitor kid and liver (BUN/Creatine)
-Avoid alc
-Max 4,000 (325-650 dose)
ibuprofen/naproxen
-analgetic
-antipyretic
-anti-inflam
AE of ibuprofen
dyspepsia,GI uclers, renal tox, bronchospasm
Nurse implications ibuprof
-Allergy
-Cross hyper w/ aspirin
-400-800 dose (max 3200)
-take w/ food avoid alc
Meloxicam
-analgeic
-anti-inflam
-anti-pyretic
AE of melox
dsypena, rash, low blood, GI bleed high liver levels
Nurse implications of melox
-same as other nsaids, report rash, etc
indomethacin and ketorolac
-anti-inflam
-anti-pyretic
-analegic
AE of indo and ketorlac
GI bleed, uclers, ab pain, vomit, somlance, renal impair
Nurse im of indo and ketorlac
-hypersen to salicyte
-report pain, tarry stool, weight gain
-don’t drive
Indomethacin
listed in beers critera
Ketorolac
no more than 5 days post op (max: 120 a day)
Cross-hypersensitvity
aspirin and ibprofuen
Salicylism
signs:
-tinnitus
-dizzy
-nausea
-high temp/res
Treat:
sodium bicarb and charocal
Acetaminophen OD treatment
acetylcystenine