Analgesic/Antipyretic (CH 10) Flashcards
(38 cards)
What is pain?
Signal sent to CNS; subjective and universal; use 1-10 scale for adults and cries chart for pediatrics
Tissue injury releases….
bradykinin, histamine, prostaglandins, serotonin (all stimulate nerve endings)
Gate theory
common and well-described theory of pain; analogy of a gate to describe how injured tissues are sensed in the brain
A Fibers
Have a myelin sheath, are large fiber size, conduct quickly, are sharp and well localized
C Fibers
Have no myelin sheath, are small in fiber size, conduct slowly and are dull and nonlocalized
Endorphins
Lower pain threshold briefly
Pain Management
Treats the cause, is safe, provides effective releif
Analgesics
Relieve pain without loss of consciuousness
Opiods
Provide relief by attaching to pain receptors
Agonist
Combinen with opiod receptor to produce an analgesic response
Alternate uses of opiods
Cough suppressant: depresses respiratory center
Diarrhea treatment: slows motility of the bowels
Effects of Opiods
euphoria, NV, respiratory depression, urinary retention, diaphoresis and flushing, pupils constrict (miosis), constipation
Nursing Implications of Opiods
Get thorough history, baseline vitals and assessment. Assess for potential contraindications and drug interactions. Watch first time users for 30-45 minutes. Take oral dose with food.
Opiod Addiction
A pattern of compulsive druge use when the medication is not needed for pain. (Taper off medication)
Opiate Antagonist
Nalaxone (Narcan). Binds to opiod receptors and prevets a response. Opiods will not work for up to 24 hours after due to this blockage
ASA
Aspirin: interferes with synthesis of prostaglandins and chemical substances released from injured tissue
ASA Adverse Effects
GI irritation and bleeding, tinnitus, Reye’s Syndrome (children)
Acetaminophen Adverse Effects
overdose causes hepatic necrosis, long-term can cause nephropathy. Normal dose is 150mg/kg
Acute overdose of Acetaminophen
Treated with Acetylcysteine (smells like rotten eggs); given orally, prevents the formation of hepatotoxic metabolites
What is potentiation
two medications working together to provide therapuetic results
What will the nurse teach the client when administering methadone?
that it has an extended duration of action
What is one of the most important considerations before giving a client a PCA pump?
the clients ability to understand and follow directions
What medication would the nurse question giving throuigh and epidural?
duramorph
What medication should the nurse give if the client is allergic to aspirin?
Celebrex