Anatomy, aphasia, consciousness and memory Flashcards

(34 cards)

1
Q

Parts of midbrain (Micky mouse)

A
Ears - cerebral peduncles
Eyebrows - substantia nigra 
Eyes - red nuclei (axons of CNVIII)
Nose - CNVIII nuclei
Mouth - cerebral aqueduct
Around mouth - PAG
Chin - superior calliculi and tectum 
Tears - ascending tracts
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2
Q

Functions of frontal lobe of cortex

A
Motor function
Speech expression
Inhibition
Cognition
Eye movements
Continence
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3
Q

Functions of parietal lobe of cortex

A

Sensory function
Speech comprehension
Attention - awareness of environment
Calculation

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4
Q

Functions of temporal lobe of cortex

A

Hearing
Olfaction
Memory
Emotion

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5
Q

Functions of occipital lobe of cortex

A

Vision

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6
Q

What is cerebral dominance

A

95% have left hemisphere dominance
Meaning left side is responsible for sequential processing e.g language and logic
Right side is responsible for whole picture processing e.g body image, attention and emotion

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7
Q

What areas are used in the language pathways

A

Wernicke’s area in temporal lobe

Broca’s area in inferolateral frontal lobe

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8
Q

Function of Broca’s area

A

Production of speech, is anatomically adjacent to motor part of frontal lobe controlling face

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9
Q

Function of Wernicke’s area

A

Interpretation of speech

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10
Q

What connects Broca’s and Wernicke’s area

A

Arcuate fasciculus

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11
Q

Differentiate Broca’s and Wernicke’s aphasia

A

Broca’s - can understand instructions and follow them but answers to questions are incomprehensible

Wernicke’s - can speak fluently but answers to questions are inappropriate

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12
Q

Classes of memory

A

Explicit or declarative (factual)

Implicit or nondeclarative (motor skills and emotion)

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13
Q

Where are the types of memory stored in general

A

Explicit in cortex

Implicit in cerebellum

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14
Q

What increases consolidation of memory into long term memories

A

Emotional context
Rehearsal
Association

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15
Q

Function of hippocampus in consolidating memory

A

Integrates input (visual, auditory, limbic) and repeats message to cortex to increase strength of connection via increased neurotransmitter release and increased presynaptic branches

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16
Q

What is arousal and consciousness

A

Arousal - emotional state associated with a goal or avoidance of a noxious stimulus

Consciousness - awareness of external world and internal states

17
Q

How is consciousness controlled

A

Cortex stimulates the reticular formulation which then stimulates the cortex creating a positive feedback loop

18
Q

What is the reticular formation

What are the inputs and outputs

A

Population of specialised interneurones in the brainstem receiving input from the sensory system and cortex
Output to reticular activating system

19
Q

What is contained in the RAS and what stimulates the cortex in each case

A

Thalamus - glutamate
Hypothalamus - histamine
Basal forebrain nuclei - acetylcholine

20
Q

How to assess consciousness

A

GCS: /4 eye opening, /6 motor response, /5 verbal response

Electroencephalogram

21
Q

Describe brain death

A

Flat EEG

Widespread cortical and brainstem damage

22
Q

Describe coma

A

Disordered EEG, no detectable sleep wake cycle, unresponsive to psychologically meaningful stimuli
Widespread cortical and brainstem damage

23
Q

Describe post vegetative state

A

Disordered EEG, detectable sleep wake cycle, brain stem reflexes present, spontaneous eye opening
Widespread cortical damage

24
Q

Describe locked in syndrome

A

All somatic motor functions are lost from pons down (eye movements may be preserved)
Basilar or pontine artery occlusion

25
How does sleep occur
Inhibition of positive feedback between cortex and RAS leads to decreased cortical activity Possibly due to removal of sensory input
26
What are the stages of sleep
6 cycles of progression from awake to stage 4 with periodic rapid changes to REM
27
What changes from stage 1-4
Cortical neuronal frequency decreases and amplitude increases because of synchronicity
28
What happens in REM
Muscle tone of body lost due to RF and reticulospinal tract | Eye movements, CN functions e.g bruxism, and autonomic functions e.g erection are preserved
29
What stimulates REM
Neurones in the pons
30
Type of waves present in each stage of sleep
``` REM/awake - beta Eyes closed - alpha Stage 1 - alpha and beta Stage 2-3 - theta, sleep spindles and k complexes Stage 4 - delta waves ```
31
What are sleep spindles
Thalamic activity during sleep aiming to 'wake' cortex
32
What are k complexes
First signs of intrinsic rate during sleep
33
Functions of sleep
Bodily repair Clearing extracellular debris Memory consolidation
34
Describe sleep apnoea
Excessive daytime sleepiness due to hypoxia episodes waking you up at night Main cause is obesity