Anatomy - NS

Question 1

Describe Phenylephrine

Answer 1

A selective alpha-1 adrenergic receptor agonist - used primarily as a decongestant. Used to dilate the pupil and increase blood pressure.

Question 2

Phyenylephrine is marketed as a substitute for which drug?

Answer 2

pseudoephedrine.

Question 3

What is oral phenylephrine metabolised by?

Answer 3

monoamine oxidase

Question 4

What is an Alpha-1 adrenergic receptor?

Answer 4

a G-protein-coupled receptor (GPCR) associated with the Gq heterotrimeric G-protein. Consisting of 3 highly homologous subtypes Alpha 1a, Alpha 1b, and Alpha 1d adrenergic receptors. Catecholamines like norepinephrine and epinephrine signal through it in the cns and pns.

Question 5

How is phenylephrine administered typically?

Answer 5

Either as an orally administered tablet, in liquid form, or a dissolving strip.

Question 6

What are some side effects of Phenylephrine?

Answer 6

Nervousness, dizziness, sleeplessness.