Anatomy of the Skin Flashcards

(31 cards)

1
Q

How many layers of the skin are there?

A

3

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2
Q

What are the three main layers of skin called?

A

-Epidermis
-Dermis
-Hypodermis

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3
Q

What is the epidermis mainly formed from?

A

Keratinocytes undergoing terminal maturation

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4
Q

What other cells occupy the epidermis?

A

-Melanocytes
-Langerhans cells
-Merkel cells

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5
Q

What are melanocytes responsible for?

A

The are responsible for melanin production and pigment formation

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6
Q

What are Langerhans cells?

A

Antigen-presenting dendritic cells

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7
Q

What are Merkel cells?

A

Sensory mechanoreceptors

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8
Q

What is the epidermis divided into?

A

Layers of keratinocytes

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9
Q

What are the different layers of the epidermis?

A

-Stratum basale
-Stratum spinosum
-Stratum granulosum
-Stratum lucidum
-Stratum corneum

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10
Q

Which layer of the epidermis is the deepest from the surface?

A

Stratum basale

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11
Q

What occurs in the Stratum basale layer of the epidermis?

A

Mitosis of keratinocytes

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12
Q

How are keratinocytes joined in the Stratum spinosum layer of the epidermis?

A

Joined by tight intercellular junctions called desmosomes

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13
Q

What occurs in the Stratum granulosum layer of the epidermis?

A

Cells secrete lipids and other waterproofing molecules

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14
Q

What occurs in the Stratum lucidum layer of the epidermis?

A

Cells lose nuclei and drastically increase keratin production

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15
Q

What occurs in the Stratum corneum layer of the epidermis?

A

Cells lose all organelles and continue to produce keratin

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16
Q

How many days does a keratinocyte take to travel from the Stratum basale to the Stratum corneum?

17
Q

Where is the dermis found?

A

Right below the epidermis

18
Q

How many layers does the dermis have?

19
Q

What are the two layers of the dermis called?

A

-Papillary Layer
-Reticular Layer

20
Q

What function do the thicker bundles of collagen fibres have on the reticular layer of the dermis?

A

Provides durability

21
Q

What helps provide the reticular layer of the dermis durability?

A

Thicker bundles of collagen fibres

22
Q

What are some of the cell types and structures found in the dermis layer?

A

-Fibroblasts
-Mast cells
-Blood vessels and cutaneous sensory nerves
-Skin appendages

23
Q

What is the function of a fibroblast?

A

Cells which synthesis the extracellular matrix

24
Q

What are fibroblast composed of?

A

-Collagen
-Elastin

25
What are mast cells?
Histamine granule-containing cells of the innate immune system
26
What are some examples of skin appendages?
-Hair follicles -Nails -Sebaceous and sweat glands
27
What do hair follicles and sebaceous glands combine to form?
Pilosebaceous Unit
28
Where is the hypodermis layer found?
Immediately below the dermis layer
29
What is found in the hypodermis layer?
Adipose tissue
30
What is another word for adipose tissue?
Body fat
31
What are all the functions of the skin? | 7
-Defence against infections and infestations -Protection against irritants, ultraviolet irradiation and injury -Controlling water and heat loss -Important sensory organ which distinguishes pain, touch, itching, vibrations, heat and cold -Maintain body temperature -Vitamin D is also synthesised in the skin -Important organ of social communication and sexual contact.