androgen insensitivity syndrome Flashcards
(4 cards)
1
Q
what is androgen insensitivity syndrome
A
x-linked recessive condition due to end-organ resistance to testosterone causing genotypically male children to have female phenotype
2
Q
presentation of androgen insensitivity syndrome
A
primary amenorrhoea
little or no axillary and pubic hair
undescended testes
breast development
3
Q
diagnosis of androgen insensitivity syndrome
A
buccal smear or chromosomal analysis to reveal 46XY genotype
testosterone concentration
4
Q
management of androgen insensitivity syndrome
A
counselling
bilateral orchidectomy
oestrogen therapy
