ANEMIA Flashcards

(45 cards)

1
Q

GREEK WORD ETIOLOGY of ANEMIA

A

ANAIMIA “without blood”

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2
Q

Hemoglobinopathies

A

hemoglobin has impaired function

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3
Q

defined operationally as REDUCTION IN THE HEMOGLOBIN CONTENT OF THE BLOOD caused by the decrease of RBC, HEMOGLOBIN, and HEMATOCRIT

A

ANEMIA

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4
Q

MOST COMMON CAUSE OF ANEMIA

A

INSUFFICIENT IN HGB / DECREASED HGB LEVELS

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5
Q

what is the normal reference value range of blood in Liters?

A

Male: 5-6 L
Female: 4-5 L

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6
Q

Normal Hemoglobin Levels

A

Female: 12-15 g/dL
Male: 14-18 g/dL

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7
Q

<12 g/dL (HgB level in male)

A

ANEMIA

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8
Q

reference value that indicates a female person is suspected to have an anemia

A

<11 g/dL

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9
Q

formula for MCV

A

MCV = (Hct/RBC Count) x 10

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10
Q

formula for MCH

A

MCH = (HgB/RBC Count) x 10

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11
Q

formula for MCHC

A

MCHC = (Hgb/Hct) x 100

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12
Q

unit of measurement for MCV

A

fL or 10^-15

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13
Q

unit of measurement for MCH

A

pg or 10^-12

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14
Q

unit of measurement for MCHC

A

g/dL or L/L or %

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15
Q

MCV:

<80 fL

A

MICROCYTIC

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16
Q

MCV:

> 100 fL

A

MACROCYTIC

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17
Q

MCH reference value

A

26-32 pg

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18
Q

MCHC:

32-36 g/dL

A

NORMOCHROMIC

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19
Q

MCHC:

<32 g/dL

20
Q

MCHC:

> 36 g/dL

21
Q

HOW ARE ANEMIAS CLASSIFIED?

A

by its MORPHOLOGY and CAUSE/ETIOLOGY

22
Q

2 TYPES OF ANEMIA

A

RELATIVE (PSEUDO) ANEMIA AND ABSOLUTE ANEMIA

23
Q

other term for relative (pseudo anemia)

24
Q

other term for absolute anemia

25
type of anemia that has normal RBC mass but has increased plasma volume
FALSE ANEMIA/RELATIVE (PSEUDO) ANEMIA
26
type of anemia that is SECONDARY TO AN UNRELATED CONDITION AND CAN BE TRANSIENT IN NATURE
FALSE ANEMIA/RELATIVE (PSEUDO) ANEMIA
27
type of anemia in relative (pseudo) anemia based on the MCV and MCHC volume
NORMOCYTIC/NORMOCHROMIC ANEMIA
28
pregnancy and volume overload because of multiple transfusions can cause ___ (type of anemia)
RELATIVE (PSEUDO) ANEMIA / FALSE ANEMIA
29
type of anemia that has DECREASED RBC MASS but normal plasma volume (has high retics)
ABSOLUTE ANEMIA / TRUE ANEMIA
30
INDICATIVE OF A TRUE DECREASE IN ERYTHROCYTES AND HEMOGLOBIN
ABSOLUTE ANEMIA / TRUE ANEMIA
31
This can cause increased loss of red cells from the circulation
- acute bleeding (traumatic injuries) | - accelerated destruction (hemolytic)
32
the term in which the patient has small reddish purple pinpoint spots (leakage of blood)
skin (petechiae)
33
general classification of anemia in which the hemoglobin concentration is at 7-10 g/dL
MODERATE ANEMIA
34
signs and symptoms of a patient that has moderate anemia
DYSPNEA, VERTIGO, HEADACHE, MUSCLE WEAKNESS, AND LETHARGY
35
a patient has hemoglobin concentration below 7 g/dL, what is the general classification of anemia the patient has?
SEVERE ANEMIA
36
signs and symptoms of a patient that has severe anemia
MODERATE ANEMIA + TACHYCARDIA + HYPOTENSION
37
general classification of anemia that may cause pallor of conjunctivae and nail beds
moderate anemia
38
how can the body adapt when the anemia is caused by slow loss of blood?
decreased in hemoglobin-oxygen affinity by increasing the production of 2,3 DPG/BPG -BODY ADAPTATION: INCREASED IN ERYTHROPOEITIN PRODUCTION OF KIDNEYS
39
what are the MECHANISMS OF ANEMIA
1. INEFFECTIVE and INSUFFICIENT ERYTHROPOEISIS | 2. BLOOD LOSS AND HEMOLYSIS
40
what are the defective erythroid precursor cells being produced in ineffective erythropoiesis?
BFU-E to CFU-E
41
in ineffective erythropoeisis, these defective precursors undergo _____ in the bone marrow before they mature into reticulocyte and be released into the peripheral circulation
APOPTOSIS
42
NORMAL REFERENCE VALUE FOR MCV
80-100 fL
43
NORMAL REFERENCE VALUE FOR MCV
32-36 g/dL
44
conditions related to ineffective and insufficient erythropoiesis
MEGALOBLASTIC ANEMIA THALASSEMIA SIDEROBLASTIC ANEMIA
45
deficient DNA synthesis due to vitamin b12 and folate/folic acid deficiency
MEGALOBLASTIC ANEMIA