Anemias

Question 1

Anemia is not a diagnosis
True or false

Answer 1

True

Question 2

Cut-off Hb for normal ranges are arbitrary
Normal ranges depend on age, environment, physiologic state
True or false

Answer 2

True

Question 3

In general what is the normal range of Hb in males, females and children

Answer 3

Normal Hemoglobin (Hgb)- In general, the normal ranges are as follows:
•13.5 to 18.0 g/dL in men
•12.0 to 15.0 g/dL in women
•11.0 to 16.0 g/dL in children
•Varied in pregnancy depending on the trimester, but generally greater than 10.0 g/dL

Question 4

The body at rest approximately uses how much ml of oxygen in the blood

Answer 4

250

Question 5

O2 delivery can fall with a reduction in

Answer 5

Cardiac output
Hb concentration
O2 saturation

Question 6

What are the organs most sensitive to hypoxia

Answer 6

Heart and brain

Question 7

What are the mechanisms of anemia

Answer 7

Reduced red-cell production
- defective precursor proliferation
- defective precursor maturation
- defective proliferation and maturation
Increased RBC destruction
RBC loss from circulation

Question 8

What conditions could lead to reduced proliferation of precursors

Answer 8

Reduced proliferation of precursors
Fe-deficiency
Anaemia of chronic disorders; Ca, infection, inflammation
Reduced EPO production; renal disease
Reduced O2 requirements; hypothyroidism, hypopituitarism
Reduced O2 affinity for Hb
Bone marrow disorders; aplasia, pure RBC aplasia, infiltrative disorders