Anesthesia II Flashcards

1
Q

What is the triad of anesthesia?

A

Sedation
Loss of Pain
Muscle weakness

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2
Q

Class 1 ASA?

A

Normal healthy

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3
Q

Class 2 ASA

A

Mild systemic disease

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4
Q

Class 3 ASA

A

Severe systemic disease
(Uncontrolled diabetes, etc)
Not incaacitating

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5
Q

Class 4 ASA

A

incapacatating systemic disease threatening life

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6
Q

Stage 1 of anesthesia is known as?

A
This is known as the amnesia stage!
Three planes:
1:Preanalgesia, memory and sensation intact
2: Partial amnesia and analgesia
3: Total amnesia and analgesia
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7
Q

What is stage 2 of anesthesia?

A

Stage 2 is delerium

Unconsciousness, mydriasis, irregular breathing, involuntary movements

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8
Q

What is stage 3 of anesthesia known as?

A

Known as surgical anesthesia!
Broken into 3 planes
1: Sleeping with faint lid reflex and eye focused centrally/ regular breathing.

2: Partial intercostal paralysis, tachycardia, hypotension, hypotonia
3: Complete intercostal paralysis and respiratory arrest

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9
Q

What is stage 4 of anesthesia known as?

A

This is the medullary paralysis and is not good!

Plane 1: Reversible
Plane 2: irreversable

Causes respiratory and cardiac failure

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10
Q

What are the major first signs of malignant hyperthermia?

A

TACHYCARDIA

Sweating, muscle rigidity etc.

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11
Q

What is the treatment for malignant hyperthermia?

A

Sodium Dantrolene 2.5 mg/kg

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12
Q

Which two medications can put a patient at risk for malignant hyperthermia?

A

Halothane

Succinylcholine

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13
Q

Inhalated agents with increased risk of spontaneous abortion?

A

Diethyl Ether

Chloroform

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14
Q

Does halothane effect the liver or the kidneys?

A

LIVER
H FOR HEPATIC

Also may trigger malignant hyperthermia, myocardial depression, and arythmias.

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15
Q

What is good about halothane?

A
Most potent inhalation
Lowest MAC
Rapid smooth induction and recovery
Pleasant smell
Non-irritating/emetic/and safe in asthmatics.
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16
Q

What are the pros and cons of Isoflurane?

A

Rapid induction, good muscle relaxant, heart rhythm safe, and compatible with epinephrine.

Cons: post op shivering, possible delayed hepatic damage.

17
Q

Which inhalation agent is known to cause seizures?

A

Enflurane!!

It is also nephrotoxic and hepatotoxic

18
Q

Which inhalation agents are nephrotoxic?

A

Enflurane (hepato and nephro)
and
Methoxyflurane.

19
Q

The higher the MAC for an agent the …

A

The least potent the agent.

MAC = The lowest possible dose to limit movement in 50% of patients.

20
Q

What is the dose per kg for lidocaine?

21
Q

What is the dose per kg for lidocaine with epi?

22
Q

What is the dose per kg for marcaine?

23
Q

How many mg/mL of epinephrine is in 1:1000?

A

In a solution of 1:1000 there is 1 mg/mL of epinephrine.

24
Q

What type of local is contraindicated with the use of halothane?

A

Should not use epinephrine halothane sensitizes the heart

25
What is clark's rule?
Pediatric local dosing. weight of child in lbs / 150 x ( adult dose)
26
Why are intravenous anesthetics used before inhalation agents?
Intravenous agents do not cause as much muscle relaxation/breathing supression. Its best to initiate with IV and then follow up with inhalation products.
27
Why is ketamine so nephrotoxic?
It is one of the few intravenous agents that is not bound to albumin. Thus it is cleared by the kidneys instead of the liver!
28
Why is the recovery from diprivan (propofol) quicker than any other induction agent?
Because propofol is quickly cleared by the liver at a rapid rate.
29
What is the moa of ketamine?
NMDA antagonist
30
What trifecta does ketamine provide patients?
Hypnotic Analgesia Amnesia Also hallucinogenic with dissociative amnesia.
31
Why is ketamine useful in trauma cases?
Has no effect on the heart! | Prevents any drops in blood pressure!
32
Safest anesthetic for people with cardiac issues and asthma?
Etomidate
33
Antidote for benzodiazepines?
Flumazenil 0.2 mg/kg
34
Another name for versed?
Midazolam | Sedative, hypnotic, amnesia.
35
Whats the differnce between versed and valium?
Both are benzos but... Versed (midazolam) allows hypnotic effects. Valium allows for anti anxiety effects!
36
What drug can reverse narcotic overdose?
Naloxone!
37
What drug can reverse opiod antagonists?
Narcan